• 2002
    • den Hartog, G. J. M., Vegt, E., van der Vijgh, W. J. F., Haenen, G. R. M. M., & Bast, A. (2002). Hypochlorous acid is a potent inhibitor of acetylcholinesterase. Toxicology and Applied Pharmacology, 181(3), 228-232. https://doi.org/10.1006/taap.2002.9419
    • Arts, M. J. T. J., Haenen, G. R. M. M., Wilms, L. C., Beetstra, S., Beerens - Heijnen, C. G. M., Voss, H. P., & Bast, A. (2002). Interactions between flavonoids and proteins: effect on the total antioxidant capacity. Journal of Agricultural and Food Chemistry, 50(5), 1184-1187. https://doi.org/10.1021/jf010855a
    • Boots, A. W., Haenen, G. R. M. M., den Hartog, G. J. M., & Bast, A. (2002). Oxidative damage shifts from lipid peroxidation to thiol arylation by catechol-containing antioxidants. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1583(3), 279-284. https://doi.org/10.1016/S1388-1981(02)00247-0
    • de Kort, J., Haenen, G. R. M. M., Bast, A., Koek, G. H., & Barnes , E. (2002). Oxidative stress in patients with active HCV infection. Hepatology, 36(4), 743. https://doi.org/10.1053/jhep.2002.35344
    • Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Oostveen, R. M., Stalpers, E. M., & Bast, A. (2002). Protection of flavonoids against lipid peroxidation: the structure activity relationship revisited. Free Radical Research, 36(5), 575-581. https://doi.org/10.1080/10715760290025951
    • Rezk, B. M., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2002). The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids. Biochemical and Biophysical Research Communications, 295(1), 9-13. https://doi.org/10.1016/S0006-291X(02)00618-6
    • Dallinga, J. W., Haenen, G. R. M. M., Bast, A., & van Schooten, F. J. (2002). The effect of the trolox equivalent antioxidant capacity (TEAC) in plasma on the formation of 4-aminobiphenylhaemoglobin adducts in smokers. Biomarkers, 7(4), 291-298. https://doi.org/10.1080/13547500210148306
    • Bast, A., & Haenen, G. R. M. M. (2002). The toxicity of antioxidants and their metabolites. Environmental Toxicology and Pharmacology, 11, 251-258. https://doi.org/10.1016/S1382-6689(01)00118-1
    • Haenen, G. R. M. M., & Bast, A. (2002). The use of vitamin supplements in self-medication. Therapie, 57(2), 119-122. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12185958&dopt=Abstract
    • van Haaften, R. I. M., Haenen, G. R. M. M., Evelo, C. T. A., & Bast, A. (2002). Tocotrienols inhibit human glutathione S-transferase P1-1. Iubmb Life, 54(2), 81-84. https://doi.org/10.1080/15216540214315
  • 2001
    • van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M., & Bast, A. (2001). alpha-Tocopherol inhibits human glutathione S-transferase pi.Biochemical and Biophysical Research Communications, 280, 631-633. https://doi.org/10.1006/bbrc.2000.4174
    • Nia, A. B., van Schooten, F. J., Schilderman-Houba, P. A. E. L., de Kok, T. M. C. M., Haenen, G. R. M. M., van Herwijnen, M. H. M., van Agen, E., Pachen, D. M. F. A., & Kleinjans, J. C. S. (2001). A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms.Carcinogenesis, 22, 395-401. https://doi.org/10.1093/carcin/22.3.395
    • van den Berg, R., van Vliet, T., Broekmans, W. M. R., Cnubben, N. H. P., Vaes, W. H. J., Roza, L., Haenen, G. R. M. M., Bast, A., & van den Berg, H. (2001). A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers.Journal of Nutrition, 131, 1714-1722. https://doi.org/10.1093/jn/131.6.1714
    • Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., van Acker, F. A. A., van der Vijgh, W. J. F., & Bast, A. (2001). Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.Toxicology in Vitro, 15, 3-6. https://doi.org/10.1016/S0887-2333(00)00053-9
    • van Haaften, R. I. M., den Hartog, G. J. M., Evelo, C. T. A., Haenen, G. R. M. M., & Bast, A. (2001). Hypochlorous acid is a potent inhibitor of GST P1-1.Chemico-Biological Interactions, 138, 77-83. https://doi.org/10.1016/S0009-2797(01)00262-9
    • van Haaften, R. I. M., Evelo, C. T. A., Penders, J., Eijnwachter, M., Haenen, G. R. M. M., & Bast, A. (2001). Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivatives.Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1548, 23-28. https://doi.org/10.1016/S0167-4838(01)00211-4
    • Arts, M. J. T. J., Haenen, G. R. M. M., Voss, H. P., & Bast, A. (2001). Masking of antioxidant capacity by the interaction of flavonoids with protein.Food and Chemical Toxicology, 39, 787-791. https://doi.org/10.1016/S0278-6915(01)00020-5
    • van Acker, F. A. A., Hulshof, J., Haenen, G. R. M. M., Menge, W. M. P. B., van der Vijgh, W. J. F., & Bast, A. (2001). New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity.Free Radical Biology and Medicine, 31, 31-37. https://doi.org/10.1016/S0891-5849(01)00546-9
    • Drent, M., van den Berg, R., Haenen, G. R. M. M., van den Berg, H., Wouters, E. F. M., & Bast, A. (2001). NF-kappaB activation in sarcoidosis.Sarcoidosis Vasculitis and Diffuse Lung Diseases, 18(1), 50-56. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11354547&dopt=Abstract
    • van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M., & Bast, A. (2001). No reduction of alpha-tocopherol quinone by glutathione in rat liver microsomes. Biochemical Pharmacology, 61, 715-719. https://doi.org/10.1016/S0006-2952(01)00545-7
    • van den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (2001). Nuclear factor-kappaB activation is higher in peripheral blood mononuclear cells of male smokers.Environmental Toxicology and Pharmacology, 9, 147-151. https://doi.org/10.1016/S1382-6689(00)00070-3
    • Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Vekemans, J., & Bast, A. (2001). Peroxynitrite scavenging of flavonoids: structure activity relationship. Environmental Toxicology and Pharmacology, 10, 199-206. https://doi.org/10.1016/S1382-6689(01)00083-7
    • Rhemrev, J. P. T., Vermeiden, J. P. W., Haenen, G. R. M. M., de Bruijne, J., Rekers-Mombarg, L., & Bast, A. (2001). Progressively motile human spermatozoa are well protected against in vitro lipid peroxidation imposed by induced oxidative stress.Andrologia, 33, 151-158. https://doi.org/10.1046/j.1439-0272.2001.00430.x
    • Ostby, O. B., Gundersen, L. L., Rise, F., Antonson, O., Fosnes, K., Larsen, V., Bast, A., Custers, I., & Haenen, G. R. M. M. (2001). Synthesis of 5-substituted pyrrolo[1,2-b]pyridazines with antioxidant properties. Archiv der Pharmazie, 334, 21-24. https://doi.org/10.1002/1521-4184(200101)334:1<21::AID-ARDP21>3.0.CO;2-W
    • Keularts, I. M. L. W., Zivelin, A., Seligsohn, U., Hemker, H. C., & Béguin, S. (2001). The role of factor XI in thrombin generation induced by low concentrations of tissue factor.Thrombosis and Haemostasis, 85, 1060-1065. https://doi.org/10.1055/s-0037-1615964
    • van den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (2001). Transcription factor NF-kappaB as a potential biomarker for oxidative stress.British Journal of Nutrition, 86 suppl 1, S121-S127. https://doi.org/10.1079/BJN2001340
  • 2000
    • van Acker, F. A. A., van Acker, S. A. B. E., Kramer, K., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2000). 7-monohydroxyethylrutoside protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week. Clinical Cancer Research, 6(4), 1337-1347. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10778960&dopt=Abstract
    • Keularts, I. M. L. W., van Gorp Beisser, R. M. A., Feijge, M. A. H., Vuist, M. W. J., & Heemskerk, J. W. M. (2000). alpha2A-Adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels. Journal of Biological Chemistry, 275(3), 1763-1772. https://doi.org/10.1074/jbc.275.3.1763
    • Heunks, L. M. A., Bast, A., van Herwaarden, C. L. A., Haenen, G. R. M. M., & Dekhuijzen, P. N. R. (2000). Effects of emphysema and training on glutathione oxidation in the hamster diaphragm. Journal of Applied Physiology, 88, 2054-2061. https://doi.org/10.1152/jappl.2000.88.6.2054
    • van Acker, F. A. A., Schouten, O., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2000). Flavonoids can replace alpha-tocopherol as an antioxidant. Febs Letters, 473, 145-148. https://doi.org/10.1016/S0014-5793(00)01517-9
    • van Acker, F. A. A., van Acker, S. A. B. E., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2000). In vitro screening of antitumour agents for cardiotoxicity by means of isolated mouse left atria. Anticancer Research, 20(6B), 4483-4487. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11205292&dopt=Abstract
    • Paquay, J. B. G., Haenen, G. R. M. M., Stender, G., Wiseman, S. A., Tijburg, L. B. M., & Bast, A. (2000). Protection against nitric oxide toxicity by tea. Journal of Agricultural and Food Chemistry, 48, 5768-5772. https://doi.org/10.1021/jf981316h
    • Rhemrev, J. P. T., van Overveld, F. W. P. C., Haenen, G. R. M. M., Teerlink, T., Bast, A., & Vermeiden, J. P. W. (2000). Quantification of the nonenzymatic fast and slow TRAP in a postaddition assay in human seminal plasma and the antioxidant contributions of various seminal compounds. Journal of Andrology, 21, 913-920. https://doi.org/10.1002/j.1939-4640.2000.tb03422.x
    • Vreman, H. J., Haenen, G. R. M. M., Stevenson, D. K., & Bast, A. (2000). Reduction of the NO-mediated response in the rat aorta by metalloporphyrins. Canadian Journal of Physiology and Pharmacology, 78, 457-461. https://doi.org/10.1139/y00-009
    • Ystby, O. B., Dalhus, B., Gundersen, L. L., Rise, F., Bast, A., & Haenen, G. R. M. M. (2000). Synthesis of 1-substituted 7-cyano-2,3-diphenylindolizines and evaluation of antioxidant properties. European Journal of Organic Chemistry, 3763-3770. https://doi.org/10.1002/1099-0690(200011)2000:22<3763::AID-EJOC3763>3.0.CO;2-S
    • van Acker, F. A. A., Hageman, G. J., Haenen, G. R. M. M., van der Vijgh, W. J. F., Bast, A., & Menge, W. M. P. B. (2000). Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity. Journal of Medicinal Chemistry, 43, 3752-3760. https://doi.org/10.1021/jm000951n
    • Keularts, I. M. L. W., Hamulyak, K., Hemker, H. C., & Béguin, S. (2000). The effect of DDAVP infusion On thrombin generation in platelet-rich plasma of von Willebrand type 1 and in mild haemophilia A patients. Thrombosis and Haemostasis, 84(4). https://doi.org/10.1055/s-0037-1614080
    • Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Wiseman, S. A., & Tijburg, L. B. M. (2000). The interaction of tea flavonoids with the NO-system: disrimination between good and bad NO. Food Chemistry, 70, 365-370. https://doi.org/10.1016/S0308-8146(00)00105-9
    • van den Berg, R., Haenen, G. R. M. M., van den Berg, H., van der Vijgh, W. J. F., & Bast, A. (2000). The predictive value of the antioxidant capacity of structurally related flavonoids using the Trolox equivalent antioxidant capacity TEAC assay. Food Chemistry, 70, 391-395. https://doi.org/10.1016/S0308-8146(00)00092-3
    • Vliet, L. A., Rodenhuis, N., Wikstrom, H., Pugsley, T. A., Serpa, K. A., Meltzer, L. T., Heffner, T. G., Wise, L. D., Laijness, M. E., Huff, R. M., Svensson, K., Haenen, G. R. M. M., & Bast, A. (2000). Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists. Journal of Medicinal Chemistry, 43, 3549-3557. https://doi.org/10.1021/jm000087z
    • van Overveld, F. W. P. C., Haenen, G. R. M. M., Rhemrev, J. P. T., Vermeiden, J. P. W., & Bast, A. (2000). Tyrosine as important contributor to the antioxidant capacity of seminal plasma. Chemico-Biological Interactions, 127, 151-161. https://doi.org/10.1016/S0009-2797(00)00179-4
  • 1999
    • van den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (1999). Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures.Food Chemistry, 66(4), 511-518. https://doi.org/10.1016/S0308-8146(99)00089-8
    • Haenen, G. R. M. M., & Bast, A. (1999). Nitric Oxide Radical Scavenging of Flavonoids. Methods in Enzymology, 301, 490-503. https://doi.org/10.1016/S0076-6879(99)01112-X
    • Paquay, J. B. G., Hoen, P. A., Bast, A., Timmerman, H., & Haenen, G. R. M. M. (1999). Nitric oxide synthase inhibition by dimaprit and dimaprit analogues.British Journal of Pharmacology, 127(2), 331-334. https://doi.org/10.1038/sj.bjp.0702552
    • Beguin, S., Kumar, R., Keularts, I., Seligsohn, U., Coller, B. S., & Hemker, H. C. (1999). Fibrin-dependent platelet procoagulant activity requires GPIb receptors and von Willebrand factor. Blood, 93(2), 564-570. https://doi.org/10.1182/blood.V93.2.564
  • 1998
    • Keularts, I. M. L. W., Beguin, S., de Zwaan, C., & Hemker, H. C. (1998). Treatment with a GPIIb/IIIa antagonist inhibits thrombin generation in platelet rich plasma from patients. Thrombosis and Haemostasis, 80(3), 370-371. https://doi.org/10.1055/s-0037-1615213
  • 1997
    • Luik, A. J., van Kuijk, W. H. M., Spek, J., de Heer, F., van Bortel, L. M., Schiffers, P. M. H., van Hooff, J. P., & Leunissen, K. M. L. (1997). Effects of hypervolemia on interdialytic hemodynamics and blood pressure control in hemodialysis patients.American Journal of Kidney Diseases, 30(4), 466-474. https://doi.org/10.1016/S0272-6386(97)90303-6