• 2007
    • Rietjens, S. J., Bast, A., & Haenen, G. R. (2007). New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol. Journal of Agricultural and Food Chemistry, 55(18), 7609-7614. https://doi.org/10.1021/jf0706934
    • Arts, M. J., Grun, C., Jong, R. L., Voss, H. P., Bast, A., Mueller, M. J., & Haenen, G. R. (2007). Oxidative Degradation of Lipids during Mashing. Journal of Agricultural and Food Chemistry, 55(17), 7010-7014. https://doi.org/10.1021/jf070505+
    • de Jongh, R., Haenen, G. R., van Koeveringe, G. A., Dambros, M., de Mey, J. G., & van Kerrebroeck, P. E. V. A. (2007). Oxidative stress reduces the muscarinic receptor function in the urinary bladder. Neurourology and Urodynamics, 26(2), 302-308. https://doi.org/10.1002/nau.20298
    • Bast, A., Haenen, G. R., Bruynzeel, A. M., & van der Vijgh, W. J. (2007). Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials. Cardiovascular Toxicology, 7(2), 154-159. https://doi.org/10.1007/s12012-007-0018-0
    • Bast, A., Kaiserova, H., den Hartog, G. J., Haenen, G. R., & van der Vijgh, W. J. (2007). Protectors against doxorubicin-induced cardiotoxicity: Flavonoids. Cell Biology and Toxicology, 23(1), 39-47. https://doi.org/10.1007/s10565-006-0139-4
    • Rietjens, S. J., Bast, A., Vente, J. D., & Haenen, G. (2007). The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress induced impairment of the NO{middle dot} response of isolated rat aorta. American Journal of Physiology-heart and Circulatory Physiology, 292(4), H1931-H1936. https://doi.org/10.1152/ajpheart.00755.2006
    • Boots, A. W., Li, H., Schins, R. P., Heemskerk, J. W., Bast, A., & Haenen, G. R. (2007). The quercetin paradox. Toxicology and Applied Pharmacology, 222(1), 89-96. https://doi.org/10.1016/j.taap.2007.04.004
  • 2006
    • van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M., & Evelo, C. T. (2006). Biologically relevant effects of mRNA amplification on gene expression profiles. BMC Bioinformatics, 7, 200. https://doi.org/10.1186/1471-2105-7-200
    • Goossens, G. H., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2006). Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects. Diabetologia, 49(12), 3009-3016. https://doi.org/10.1007/s00125-006-0458-2
    • Coleman, M. D., Williams, C., & Haenen, G. R. (2006). Effects of Lipoic Acid and Dihydrolipoic Acid on 4-Aminophenol-Mediated Erythrocytic Toxicity in vitro*. Basic & Clinical Pharmacology & Toxicology, 99(3), 225-229. https://doi.org/10.1111/j.1742-7843.2006.pto_499.x
    • Vaisman, N., Haenen, G. R., Zaruk, Y., Verduyn, C., Bindels, J. G., Verlaan, S., & Meijer, E. P. (2006). Enteral feeding enriched with carotenoids normalizes the carotenoid status and reduces oxidative stress in long-term enterally fed patients. Clinical Nutrition, 25(6), 897-905. https://doi.org/10.1016/j.clnu.2006.06.002
    • van Empel, V. P. M., Bertrand, A. T., van Oort, R. J., van der Nagel, R., Engelen, M. P. K. J., van Rijen, H. V., Doevendans, P. A. F. M., Crijns, H. J. G. M., Ackerman, S. L., Sluiter, W., & de Windt, L. J. (2006). EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. Journal of the American College of Cardiology, 48(4), 824-832. https://doi.org/10.1016/j.jacc.2006.02.075
    • Troost, F. J., Brummer, R. J., Haenen, G. R., Bast, A., van Haaften, R. I. M., Evelo, C. T., & Saris, W. H. (2006). Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress. Physiological genomics, 25(2), 242-249. https://doi.org/10.1152/physiolgenomics.00114.2005
    • Haenen, G. R., Arts, M. J. T., Bast, A., & Coleman, M. D. (2006). Structure and activity in assessing antioxidant activity in vitro and in vivo. A critical appraisal illustrated with the flavenoids. Environmental Toxicology and Pharmacology, 21, 191-198. https://doi.org/10.1016/j.etap.2005.07.010
  • 2005
    • Gosker, H. R., Bast, A., Haenen, G. R. M. M., Fischer, M. A. J. G., van der Vusse, G. J., Wouters, E. F. M., & Schols, A. M. W. J. (2005). Altered antioxidant status in peripheral skeletal muscle of patients with COPD. Respiratory Medicine, 99, 118-125. https://doi.org/10.1016/j.rmed.2004.05.018
    • Fischer, M. A. J. G., Gransier, T. J., Beckers, L. M., Bekers, O., Bast, A., & Haenen, G. R. (2005). Determination of the antioxidant capacity in blood. Clinical Chemistry and Laboratory Medicine, 43(7), 735-740. https://doi.org/10.1515/CCLM.2005.125
    • Boots, A. W., Bast, A., & Haenen, G. R. (2005). No role of DT-diaphorase (NQO1) in the protection against oxidized quercetin. Febs Letters, 579(3), 677-682. https://doi.org/10.1016/j.febslet.2004.12.044
    • Boots, A. W., Balk, J. M., Bast, A., & Haenen, G. R. (2005). The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity. Biochemical and Biophysical Research Communications, 338(2), 923-929. https://doi.org/10.1016/j.bbrc.2005.10.031
  • 2004
    • Keularts, I. M. L. W., Beguin, S., & Hemker, H. C. (2004). Gekalibreerde, geautomatiseerde trombinegeneratiecurve: Een nieuwe klinische functie-/screeningstest voor het integrale stollingssysteem. Nederlands Tijdschrift voor Geneeskunde, 148(47), 2364-. https://www.ntvg.nl/artikelen/nederlandse-vereniging-voor-klinische-chemie-en-laboratoriumgeneeskunde-0/volledig
    • Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M., & Bast, A. (2004). A new approach to assess the total antioxidant capacity using the TEAC assay. Food Chemistry, 88, 567-570. https://doi.org/10.1016/j.foodchem.2004.02.008
    • Arts, M. J. T. J., Haenen, G. R., Voss, H. P., & Bast, A. (2004). Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay. Food and Chemical Toxicology, 42(1), 45-49. https://doi.org/10.1016/j.fct.2003.08.004
    • den Hartog, G. J. M., Haenen, G. R. M. M., Boven, E., van der Vijgh, W. J. F., & Bast, A. (2004). Lecithinized copper,zinc-superoxide dismutase as a protector against doxorubicin-induced cardiotoxicity in mice. Toxicology and Applied Pharmacology, 194(2), 180-188. https://doi.org/10.1016/j.taap.2003.09.008
    • Rezk, B. M., Haenen, G. R., van der Vijgh, W. J. F., & Bast, A. (2004). Lipoic acid protects efficiently only against a specific form of peroxynitrite-induced damage. Journal of Biological Chemistry, 279(11), 9693-9697. https://doi.org/10.1074/jbc.M312289200
    • De Celle, T., Heeringa, P., Strzelecka, A. E., Bast, A., Smits, J. F. M., & Janssen, B. J. A. (2004). Sustained protective effects of 7-monohydroxyethylrutoside in an in vivo model of cardiac ischemia-reperfusion. European Journal of Pharmacology, 494(2-3), 205-212. https://doi.org/10.1016/j.ejphar.2004.05.017
    • Rezk, B. M., Haenen, G. R., van der Vijgh, W. J. F., & Bast, A. (2004). The extraordinary antioxidant activity of vitamin E phosphate. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1683(1-3), 16-21. https://doi.org/10.1016/j.bbalip.2004.03.005
    • Michels, G., Haenen, G. R., Wätjen, W., Rietjens, S. J., & Bast, A. (2004). The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids. Toxicology Letters, 151(1), 105-111. https://doi.org/10.1016/j.toxlet.2004.01.017
    • Beguin, S., Keularts, I., Al Dieri, R., Bellucci, S., Caen, J., & Hemker, H. C. (2004). Fibrin polymerization is crucial for thrombin generation in platelet-rich plasma in a VWF-GPlb-dependent process, defective in Bernhard-Soulier syndrome. Journal of Thrombosis and Haemostasis, 2(1), 170-176. https://doi.org/10.1111/j.1538-7836.2004.00558.x
  • 2003
    • Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M., & Bast, A. (2003). A critical appraisal of the use of the antioxidant capacity (TEAC) assay in defining optimal structures. Food Chemistry, 80, 409-414. https://doi.org/10.1016/S0308-8146(02)00468-5
    • de Kok, T. M. C. M., Zwingman, I., Moonen, E. J. C., Schilderman-Houba, P. A. E. L., Rhijnsburger, E. H., Haenen, G. R. M. M., & Kleinjans, J. C. S. (2003). Analysis of oxidative DNA damage after human dietary supplementation with linoleic acid. Food and Chemical Toxicology, 41(3), 351-358. https://doi.org/10.1016/S0278-6915(02)00237-5
    • Abou el Hassan, M. A., Kedde, M., Zwiers, U. T., Tourn, E., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2003). Bioavailability and pharmacokinetics of the cardioprotecting flavonoid 7-monohydroxyethylrutoside in mice. Cancer Chemotherapy and Pharmacology, 52(5), 371-376. https://doi.org/10.1007/s00280-003-0667-z
    • van Haaften, R. I. M., Haenen, G. R. M. M., Evelo, C. T. A., & Bast, A. (2003). Effect of vitamin E on glutathione-dependent enzymes. Drug Metabolism Reviews, 35(2-3), 215-253. https://doi.org/10.1081/DMR-120024086
    • van Haaften, R. I. M., Haenen, G. R. M. M., van Bladeren, P. J., Bogaards, J. J., Evelo, C. T. A., & Bast, A. (2003). Inhibition of various glutathione S-transferase isoenzymes by RRR-alpha-tocopherol. Toxicology in Vitro, 17(3), 245-251. https://doi.org/10.1016/S0887-2333(03)00038-9
    • den Hartog, G. J. M., Boots, A. W., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2003). Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin. Toxicology in Vitro, 17(2), 165-167. https://doi.org/10.1016/S0887-2333(03)00007-9
    • Bast, A., & Haenen, G. R. M. M. (2003). Lipoic acid: a multifunctional antioxidant. Biofactors, 17(1-4), 207-213. https://doi.org/10.1002/biof.5520170120
    • Troost, F. J. J., Saris, W. H. M., Haenen, G. R. M. M., Bast, A., & Brummer, R. J. M. (2003). New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application. American Journal of Physiology-Gastrointestinal and Liver Physiology, 285(2), G354-G359. https://doi.org/10.1152/ajpgi.00422.2002
    • Hallemeesch, M. M., Janssen, B. J. A., de Jonge, W. J., Soeters, P. B., Lamers, W. H., & Deutz, N. E. P. (2003). NO production by cNOS and iNOS reflects blood pressure changes in LPS-challenged mice. American Journal of Physiology : Endocrinology and Metabolism, 285(4), E871-E875. https://doi.org/10.1152/ajpendo.00004.2002
    • Boots, A. W., Haenen, G. R. M. M., & Bast, A. (2003). Oxidant metabolism in chronic obstructive pulmonary disease. European Respiratory Journal, 22(suppl 46), 14S-27S. https://doi.org/10.1183/09031936.03.00000403a
    • de Kort, J., Fischer, M., Haenen, G. R. M. M., Bast, A., & Koek, G. H. (2003). Oxidative stress in patients with active HCV infection compared to healthy volunteers. Journal of Hepatology, 38, 374. https://doi.org/10.1016/S0168-8278(03)80643-8
    • Boots, A. W., Knubben, N., Haenen, G. R. M. M., & Bast, A. (2003). Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation. Biochemical and Biophysical Research Communications, 308(3), 560-565. https://doi.org/10.1016/S0006-291X(03)01438-4
    • den Hartog, G. J. M., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F., & Bast, A. (2003). Superoxide dismutase: the balance between prevention and induction of oxidative damage. Chemico-Biological Interactions, 145(1), 33-39. https://doi.org/10.1016/S0009-2797(02)00160-6
    • Hageman, G. J., Larik, I., Pennings, H. J., Haenen, G. R. M. M., Wouters, E. F. M., & Bast, A. (2003). Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients. Free Radical Biology and Medicine, 35(2), 140-148. https://doi.org/10.1016/S0891-5849(03)00237-5
    • Rezk, B. M., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2003). Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore. Febs Letters, 555(3), 601-605. https://doi.org/10.1016/S0014-5793(03)01358-9
  • 2002
    • Stahl, W., van den Berg, H., Arthur, J., Bast, A., Dainty, J., Faulks, R. M., Gartner, C., Haenen, G. R. M. M., & et, A. (2002). Bioavailability and metabolism. Molecular Aspects of Medicine, 23(1-3), 39-100. https://doi.org/10.1016/S0098-2997(02)00016-X
    • Griffiths, H. R., Moller, L., Bartosz, G., Bast, A., Bertoni-Freddari, C., Collins, A., Cooke, M., Coolen, S., Haenen, G. R. M. M., Hoberg, A. M., Loft, S., Lun, J., Olinski, R., Parry, J., Pompella, A., Poulsen, H., & Verhagen, H. (2002). Biomarkers. Molecular Aspects of Medicine, 23(1-3), 101-108. https://doi.org/10.1016/S0098-2997(02)00017-1
    • Haenen, G. R. M. M., Borm, P. J. A., Knaapen, A. M., Albrecht, C., Becker, A., Hohr, D., Winzer, A., & Schins, R. P. F. (2002). DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation. Carcinogenesis, 23(7), 1111-1120. https://doi.org/10.1093/carcin/23.7.1111
    • van Schooten, F. J., Besarati Nia, A., de Flora, S., D'Agostini, F., Izzotti, A., Camoirano, A., Balm, A. J. M., Dallinga, J. W., Bast, A., Haenen, G. R. M. M., & et, A. (2002). Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers. Cancer Epidemiology Biomarkers & Prevention, 11(2), 167-175. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11867504&dopt=Abstract
    • den Hartog, G. J., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F., & Bast, A. (2002). Efficacy of HOCI scavenging by sulfurcontaining compounds: antioxidant activity of glutathione disulfide?Biological Chemistry, 383, 709-713.
    • den Hartog, G. J. M., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F., & Bast, A. (2002). Efficacy of HOCl scavenging by sulfur-containing compounds: antioxidant activity of glutathione disulfide?Biological Chemistry, 383(3-4), 709-713. https://doi.org/10.1515/BC.2002.073
    • den Hartog, G. J. M., Vegt, E., van der Vijgh, W. J. F., Haenen, G. R. M. M., & Bast, A. (2002). Hypochlorous acid is a potent inhibitor of acetylcholinesterase. Toxicology and Applied Pharmacology, 181(3), 228-232. https://doi.org/10.1006/taap.2002.9419