• 2011
    • van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P., & Heymans, S. (2011). Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology, 51(3), 318-328. https://doi.org/10.1016/j.yjmcc.2011.05.010
    • Maitland-van der Zee, A.-H., van Wieren-de Wijer, D. B. M. A., de Boer, A., Kroon, A. A., de Leeuw, P. W., Schiffers, P., Janssen, R. G. J. H., Psaty, B. M., Duijn, C. M. V., Stricker, B. H. C., & Klungel, O. H. (2011). Genetic variation in the renin-angiotensin system, use of renin-angiotensin system inhibitors and the risk of myocardial infarction. Journal of the Renin-angiotensin-aldosterone System, 12(3), 208-214. https://doi.org/10.1177/1470320310391834
    • Olieslagers, S., Pardali, E., Tchaikovski, V., ten Dijke, P., & Waltenberger, J. (2011). TGF-beta 1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus. Cardiovascular Research, 91(3), 510-518. https://doi.org/10.1093/cvr/cvr100
    • Spijkers, L. J. A., van den Akker, R. F. P., Janssen, B. J. A., Debets, J. J., De Mey, J. G. R., Stroes, E. S. G., van den Born, B.-J. H., Wijesinghe, D. S., Chalfant, C. E., MacAleese, L., Eijkel, G. B., Heeren, R. M. A., Alewijnse, A. E., & Peters, S. L. M. (2011). Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide. PLOS ONE, 6(7), 9. https://doi.org/10.1371/journal.pone.0021817
    • Meens, M. J. P. M. T., Mattheij, N. J. A., Nelissen, J., Lemkens, P., Compeer, M. G., Janssen, B. J. A., & De Mey, J. G. R. (2011). Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo. Hypertension, 58(1), 99-U181. https://doi.org/10.1161/HYPERTENSIONAHA.110.169128
    • Verkaar, F., van der Stelt, M., Blankesteijn, W. M., van der Doelen, A. A., & Zaman, G. J. R. (2011). Discovery of Novel Small Molecule Activators of beta-Catenin Signaling. PLOS ONE, 6(4), 7. https://doi.org/10.1371/journal.pone.0019185
    • Verkaar, F., van der Doelen, A. A., Smits, J. F. M., Blankesteijn, W. M., & Zaman, G. J. R. (2011). Inhibition of Wnt/beta-Catenin Signaling by p38 MAP Kinase Inhibitors Is Explained by Cross-Reactivity with Casein Kinase I delta/epsilon. Chemistry & Biology, 18(4), 485-494. https://doi.org/10.1016/j.chembiol.2011.01.015
    • el Azzouzi, H., Leptidis, S., Bourajjaj, M., Armand, A.-S., van der Nagel, R., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2011). Peroxisome Proliferator-activated Receptor (PPAR) Gene Profiling Uncovers Insulin-like Growth Factor-1 as a PPAR alpha Target Gene in Cardioprotection. Journal of Biological Chemistry, 286(16), 14598-14607. https://doi.org/10.1074/jbc.M111.220525
    • Perino, A., Ghigo, A., Ferrero, E., More, F., Santulli, G., Baillie, G. S., Damilano, F., Dunlop, A. J., Pawson, C., Walser, R., Levi, R., Altruda, F., Silengo, L., Langeberg, L. K., Neubauer, G., Heymans, S., Lembo, G., Wymann, M. P., Wetzker, R., ... Hirsch, E. (2011). Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110 gamma. Molecular Cell, 42(1), 84-95. https://doi.org/10.1016/j.molcel.2011.01.030
    • Mischke, K., Knackstedt, C., Fache, K., Reith, S., Rana, O., Saygili, E., Gemein, C., Becker, M., Marx, N., & Schauerte, P. (2011). Electrical remodelling in cardiac resynchronization therapy: decrease in intrinsic QRS duration. Acta Cardiologica, 66(2), 175-180. https://doi.org/10.1080/AC.66.2.2071248
    • Muzzarelli, S., Stricker, B. H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Brunner-La Rocca, H. (2011). Individual dosage of digoxin in patients with heart failure. QJM: An International Journal of Medicine, 104(4), 309-317. https://doi.org/10.1093/qjmed/hcq196
    • van de Vrie, M., Heymans, S., & Schroen, B. (2011). MicroRNA Involvement in Immune Activation During Heart Failure. Cardiovascular Drugs and Therapy, 25(2), 161-170. https://doi.org/10.1007/s10557-011-6291-y
    • Czepluch, F. S., Olieslagers, S., van Hulten, R., Voo, S. A., & Waltenberger, J. (2011). VEGF-A-induced chemotaxis of CD16+monocytes is decreased secondary to lower VEGFR-1 expression. Atherosclerosis, 215(2), 331-338. https://doi.org/10.1016/j.atherosclerosis.2011.01.004
    • Leventhal, M. E., Denhaerynck, K., Brunner-La Rocca, H.-P., Burnand, B., Conca, A., Bernasconi, A. T., Mahrer-Imhof, R., Froelicher, E. S., & De Geest, S. (2011). Swiss Interdisciplinary Management Programme for Heart Failure (SWIM-HF). Swiss Medical Weekly, 141, 10. https://doi.org/10.4414/smw.2011.13171
    • Snoeijs, M. G., van Bijnen, A., Swennen, E. L., Haenen, G. R. M. M., Roberts, L. J., Christiaans, M. H., Peppelenbosch, A. G., Buurman, W. A., & van Heurn, L. W. E. (2011). Tubular Epithelial Injury and Inflammation After Ischemia and Reperfusion in Human Kidney Transplantation. Annals of Surgery, 253(3), 598-604. https://doi.org/10.1097/SLA.0b013e31820d9ae9
    • Jacobs, H., Bast, A., Peters, G. J., van der Vijgh, W. J. F., & Haenen, G. R. M. M. (2011). The semisynthetic flavonoid monoHER sensitises human soft tissue sarcoma cells to doxorubicin-induced apoptosis via inhibition of nuclear factor-kappaB. British Journal of Cancer, 104(3), 437-440. https://doi.org/10.1038/sj.bjc.6606065
    • Bläuer, C., Mahrer-Imhof, R., Brunner-La Rocca, H., Mueller, C. P., Eze, G., Milbich, I., & Spirig, R. (2011). Development and Implementation of a multidisciplinary nurse-led educational programme for inpatients with heart failure: The Basel-HF-Programme: Entwicklung und Implementierung eines multidisziplinären pflegegeleiteten Programms zur stationären Betreuung von Patientinnen und Patienten mit Herzinsuffizienz: Das Basler HI-Programm. Pflege, 24(1), 29-41. https://doi.org/10.1024/1012-5302/a000089
    • Snoeijs, M. G., Vaahtera, L., de Vries, E. E., Schurink, G. W. H., Haenen, G. R. M. M., Peutz-Kootstra, C. J., Buurman, W. A., van Heurn, L. W. E., & Parkkinen, J. (2011). Addition of a water-soluble propofol formulation to preservation solution in experimental kidney transplantation. Transplantation, 92(3), 296-302. https://doi.org/10.1097/TP.0b013e3182247b78
    • Mateo Anson, N., Aura, A. M., Selinheimo, E., Mattila, I., Poutanen, K., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2011). Bioprocessing of Wheat Bran in Whole Wheat Bread Increases the Bioavailability of Phenolic Acids in Men and Exerts Antiinflammatory Effects ex Vivo.Journal of Nutrition, 141(1), 137-143. https://doi.org/10.3945/jn.110.127720
    • Jacobs, H., Peters, R., den Hartog, G. J. M., van der Vijgh, W. J. F., Bast, A., & Haenen, G. R. M. M. (2011). Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-({beta}-hydroxyethyl)-rutoside in Mice.Drug Metabolism and Disposition, 39(5), 750-756. https://doi.org/10.1124/dmd.110.036525
    • Linschooten, J. O., Laubenthal, J., Cemeli, E., Baumgartner, A., Anderson, D., Sipinen, V. E., Brunborg, G., Haenen, G. R. M. M., Fthenou, E., Briedé, J. J., van Schooten, F. J., & Godschalk, R. W. L. (2011). Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress.Reproductive Toxicology, 32(1), 106-111. https://doi.org/10.1016/j.reprotox.2011.05.004
    • Boots, A. W., Drent, M., de Boer, V. C., Bast, A., & Haenen, G. R. M. M. (2011). Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis. Clinical Nutrition, 30(4), 506-512. https://doi.org/10.1016/j.clnu.2011.01.010
    • Nabben, M., Shabalina, I. G., Kornips, C. F. P., Van Beurden, D., Cannon, B., Schrauwen, P., Nedergaard, J., & Hoeks, J. (2011). Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice.Biochimica et Biophysica Acta-bioenergetics, 1807(9), 1095-1105. https://doi.org/10.1016/j.bbabio.2011.04.003
    • Eschenhagen, T., Force, T., Ewer, M. S., De Keulenaer, G. W., Suter, T. M., Anker, S. D., Avkiran, M., de Azambuja, E., Balligand, J. L., Brutsaert, D. L., Condorelli, G., Hansen, A., Heymans, S., Hill, J. A., Hirsch, E., Hilfiker-Kleiner, D., Janssens, S., de Jong, S., Neubauer, G., ... Shah, A. M. (2011). Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 13(1), 1-10. https://doi.org/10.1093/eurjhf/hfq213
    • Czepluch, F. S., Barres, R., Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, J. R., & Waltenberger, J. (2011). Strenuous physical exercise adversely affects monocyte chemotaxis. Thrombosis and Haemostasis, 105(1), 122-130. https://doi.org/10.1160/TH10-06-0363
    • Alzand, B. S. N., Mihl, C., & La Rocca, H. P. B. (2011). Dehydration with High Natriuretic Peptide Levels! A Word of Caution. Cardiology, 118(2), 75-78. https://doi.org/10.1159/000326855
    • Constantinides, C., Mean, R., & Janssen, B. J. (2011). Effects of isoflurane anesthesia on the cardiovascular function of the C57BL/6 mouse. Ilar Journal, 52(3), e21-31.
  • 2010
    • Rother, M., Krohn, S., Kania, G., Vanhoutte, D., Eisenreich, A., Wang, X., Westermann, D., Savvatis, K., Dannemann, N., Skurk, C., Hilfiker-Kleiner, D., Cathomen, T., Fechner, H., Rauch, U., Schultheiss, H.-P., Heymans, S., Eriksson, U., Scheibenbogen, C., & Poller, W. (2010). Matricellular Signaling Molecule CCN1 Attenuates Experimental Autoimmune Myocarditis by Acting as a Novel Immune Cell Migration Modulator. Circulation, 122(25), 2688-2698. https://doi.org/10.1161/CIRCULATIONAHA.110.945261
    • Kaiser, C. A., Galatius, S., Erne, P., Eberli, F., Alber, H., Rickli, H., Pedrazzini, G., Hornig, B., Bertel, O., Bonetti, P., De Servi, S., Brunner-La Rocca, H.-P., Ricard, I., & Pfisterer, M. E. (2010). Drug-Eluting versus Bare-Metal Stents in Large Coronary Arteries. New England Journal of Medicine, 363(24), 2310-2319. https://doi.org/10.1056/NEJMoa1009406
    • Martins, P. A. D. C., Salic, K., Gladka, M. M., Armand, A.-S., Leptidis, S., el Azzouzit, H., Hansen, A., Coenen-de Roo, C. J., Bierhuizen, M. F. A., van der Nagel, R., van Kuik, J., de Weger, R. A., de Bruin, A., Condorelli, G., Arbones, M. L., Eschenhagen, T., & De Windt, L. J. (2010). MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nature Cell Biology, 12(12), 1220-U231. https://doi.org/10.1038/ncb2126
    • Donners, M. P. C., Wolfs, I. M. J., Olieslagers, S., Mohammadi-Motahhari, Z., Tchaikovski, V., Heeneman, S., van Buul, J. D., Caolo, V., Molin, D. G. M., Post, M. J., & Waltenberger, J. (2010). A Disintegrin and Metalloprotease 10 Is a Novel Mediator of Vascular Endothelial Growth Factor: Induced Endothelial Cell Function in Angiogenesis and Is Associated With Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 30(11), 2188-U382. https://doi.org/10.1161/ATVBAHA.110.213124
    • van den Berg, S. A., Nabben, M., Bijland, S., Voshol, P. J., van Klinken, J. B., Havekes, L. M., Romijn, H. A., Hoeks, J., Hesselink, M. K., Schrauwen, P., & van Dijk, K. W. (2010). High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57B1/6 mice. Metabolism-Clinical and Experimental, 59(11), 1612-1618. https://doi.org/10.1016/j.metabol.2010.03.008
    • den Hengst, W. A., Gielis, J. F., Lin, J. Y., Van Schil, P. E. Y., De Windt, L. J., & Moens, A. L. (2010). Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process. American Journal of Physiology-heart and Circulatory Physiology, 299(5), H1283-H1299. https://doi.org/10.1152/ajpheart.00251.2010
    • Dargaud, Y., Spronk, H. M. H., Leenders, P., Hemker, H. C., & Ten Cate, H. (2010). Monitoring platelet dependent thrombin generation in mice. Thrombosis Research, 126(5), 436-441. https://doi.org/10.1016/j.thromres.2010.08.007
    • Maeder, M. T., Thompson, B. R., Brunner-La Rocca, H.-P., & Kaye, D. M. (2010). Hemodynamic Basis of Exercise Limitation in Patients With Heart Failure and Normal Ejection Fraction. Journal of the American College of Cardiology, 56(11), 855-863. https://doi.org/10.1016/j.jacc.2010.04.040
    • Daniels, A., van Bilsen, M., Janssen, B. J. A., Brouns, A. E., Cleutjens, J. P. M., Roemen, T. H., Schaart, G., van der Velden, J., van der Vusse, G. J., & van Nieuwenhoven, F. A. (2010). Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling. Acta Physiologica, 200(1), 11-22. https://doi.org/10.1111/j.1748-1716.2010.02102.x
    • Leenders, J. J., Wijnen, W. J., Hiller, M., van der Made, I., Lentink, V., van Leeuwen, R. E. W., Herias, V., Pokharel, S., Heymans, S., de Windt, L. J., Hoydal, M. A., Pinto, Y. M., & Creemers, E. E. (2010). Regulation of Cardiac Gene Expression by KLF15, a Repressor of Myocardin Activity. Journal of Biological Chemistry, 285(35), 27449-27456. https://doi.org/10.1074/jbc.M110.107292
    • Laeremans, H., Rensen, S. S. M., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2010). Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts. Cardiovascular Research, 87(3), 514-523. https://doi.org/10.1093/cvr/cvq067
    • Martins, P. A. D. C., Leptidis, S., Salic, K., & De Windt, L. J. (2010). MicroRNA Regulation in Cardiovascular Disease. Current Drug Targets, 11(8), 900-906. https://doi.org/10.2174/138945010791591322
    • Cosemans, J. M. E. M., Van Kruchten, R., Olieslagers, S., Schurgers, L. J., Verheyen, F. K., Munnix, I. C. A., Waltenberger, J., Angelillo-Scherrer, A., Hoylaerts, M. F., Carmeliet, P., & Heemskerk, J. W. M. (2010). Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. Journal of Thrombosis and Haemostasis, 8(8), 1797-1808. https://doi.org/10.1111/j.1538-7836.2010.03935.x
    • Storkebaum, E., de Almodovar, C. R., Meens, M., Zacchigna, S., Mazzone, M., Vanhoutte, G., Vinckier, S., Miskiewicz, K., Poesen, K., Lambrechts, D., Janssen, G. M. J., Fazzi, G. E., Verstreken, P., Haigh, J., Schiffers, P. M., Rohrer, H., Van Der Linden, A., De Mey, J. G. R., & Carmeliet, P. (2010). Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery. Circulation, 122(3), 273-U107. https://doi.org/10.1161/CIRCULATIONAHA.109.929364
    • Mensink, R. P., Jong, A., Lutjohann, D., Haenen, G. R. M., & Plat, J. (2010). Plant stanols dose-dependently decrease LDL-cholesterol concentrations, but not cholesterol-standardized fat-soluble antioxidant concentrations, at intakes up to 9 g/d. American Journal of Clinical Nutrition, 92(1), 24-33. https://doi.org/10.3945/ajcn.2009.29143
    • Meens, M. J. P. M. T., Compeer, M. G., Hackeng, T. M., van Zandvoort, M. A., Janssen, B. J. A., & De Mey, J. G. R. (2010). Stimuli of Sensory-Motor Nerves Terminate Arterial Contractile Effects of Endothelin-1 by CGRP and Dissociation of ET-1/ETA-Receptor Complexes. PLOS ONE, 5(6), 11. https://doi.org/10.1371/journal.pone.0010917
    • Nawrot, T. S., Staessen, J. A., Holvoet, P., Struijker-Boudier, H. A., Schiffers, P., Van Bortel, L. M., Fagard, R. H., Gardner, J. P., Kimura, M., & Aviv, A. (2010). Telomere length and its associations with oxidized-LDL, carotid artery distensibility and smoking. Frontiers in Bioscience, Elite edition, 2(3), 1164-1168. https://doi.org/10.2741/E176
    • Hemery, Y. M., Anson, N. M., Havenaar, R., Haenen, G. R. M. M., Noort, M. W. J., & Rouau, X. (2010). Dry-fractionation of wheat bran increases the bioaccessibility of phenolic acids in breads made from processed bran fractions. Food Research International, 43(5), 1429-1438. https://doi.org/10.1016/j.foodres.2010.04.013
    • Kuster, G. M., Nietlispach, F., Kiowski, W., Schindler, R., Bernheim, A. M., Schuetz, P., Mueller, B., Morgenthaler, N. G., Rueter, F., Riesen, W., Rickli, H., & Brunner-La Rocca, H. P. (2010). Role of RAS Inhibition in the Regulation of Cu/Zn-SOD in the Cardiac and Peripheral Arterial Beds in Humans. Clinical Pharmacology & Therapeutics, 87(6), 686-692. https://doi.org/10.1038/clpt.2010.36
    • Brouwers, O., Niessen, P. M., Haenen, G. R. M. M., Miyata, T., Brownlee, M., Stehouwer, C. D. A., de Mey, J. G. R., & Schalkwijk, C. G. (2010). Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.Diabetologia, 53(5), 989-1000. https://doi.org/10.1007/s00125-010-1677-0
    • Tijsen, A. J., Creemers, E. E., Moerland, P. D., de Windt, L. J., van der Wal, A. C., Kok, W. E., & Pinto, Y. M. (2010). MiR423-5p As a Circulating Biomarker for Heart Failure. Circulation Research, 106(6), 1035-U63. https://doi.org/10.1161/CIRCRESAHA.110.218297