van Oort, R. J., Respress, J. L., Li, N., Reynolds, C., De Almeida, A. C., Skapura, D. G., De Windt, L. J., & Wehrens, X. H. T. (2010). Accelerated Development of Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction in an RyR2-R176Q Knockin Mouse Model. Hypertension, 55(4), 932-U216. https://doi.org/10.1161/HYPERTENSIONAHA.109.146449

Muzzarelli, S., Brunner-La Rocca, H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Stricker, H. (2010). Adherence to the medical regime in patients with heart failure. European journal of heart failure, 12(4), 389-396. https://doi.org/10.1093/eurjhf/hfq015

Verkaar, F., Blankesteijn, W. M., Smits, J. F. M., & Zaman, G. J. R. (2010). beta-Galactosidase enzyme fragment complementation for the measurement of Wnt/beta-catenin signaling. Faseb Journal, 24(4), 1205-1217. https://doi.org/10.1096/fj.09-141671

McCurdy, S., Baicu, C. F., Heymans, S., & Bradshaw, A. D. (2010). Cardiac extracellular matrix remodeling: Fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC). Journal of Molecular and Cellular Cardiology, 48(3), 544-549. https://doi.org/10.1016/j.yjmcc.2009.06.018

Schalla, S., Bekkers, S. C., Dennert, R., van Suylen, R. J., Waltenberger, J., Leiner, T., Wildberger, J., Crijns, H. J., & Heymans, S. (2010). Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. European journal of heart failure, 12(3), 227-231. https://doi.org/10.1093/eurjhf/hfq004

Vanhoutte, D., & Heymans, S. (2010). TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family'. Journal of Molecular and Cellular Cardiology, 48(3), 445-453. https://doi.org/10.1016/j.yjmcc.2009.09.013

Kriemler, S., Zahner, L., Schindler, C., Meyer, U., Hartmann, T., Hebestreit, H., Brunner-La Rocca, H. P., van Mechelen, W., & Puder, J. J. (2010). Effect of school based physical activity programme (KISS) on fitness and adiposity in primary schoolchildren: cluster randomised controlled trial. BMJ, 340, 8. https://doi.org/10.1136/bmj.c785

Beljaars, C. P., Balk, J. M., Bast, A., & Haenen, G. R. (2010). Prevention of a systematic underestimation of antioxidant activity in competition assays. The impact of unspecific reactions of the reactive species.Biochemical and Biophysical Research Communications, 392(3), 346-350. https://doi.org/10.1016/j.bbrc.2010.01.022

Post, S., Smits, A. M., van den Broek, A. J., Sluijter, J. P. G., Hoefer, I. E., Janssen, B. J., Snijder, R. J., Mager, J. J., Pasterkamp, G., Mummery, C. L., Doevendans, P. A., & Goumans, M.-J. (2010). Impaired recruitment of HHT-1 mononuclear cells to the ischaemic heart is due to an altered CXCR4/CD26 balance. Cardiovascular Research, 85(3), 494-502. https://doi.org/10.1093/cvr/cvp313

Schellings, M. W. M., Vanhoutte, D., van Almen, G. C., Swinnen, M., Leenders, J. J. G., Kubben, N., van Leeuwen, R. E. W., Hofstra, L., Heymans, S., & Pinto, Y. M. (2010). Syndecan-1 Amplifies Angiotensin II-Induced Cardiac Fibrosis. Hypertension, 55(2), 249-U87. https://doi.org/10.1161/HYPERTENSIONAHA.109.137885

Dennert, R. M., van Paassen, P., Schalla, S., Kuznetsova, T., Alzand, B. S. N., Staessen, J. A., Velthuis, S., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2010). Cardiac Involvement in Churg-Strauss Syndrome. Arthritis & Rheumatism, 62(2), 627-634. https://doi.org/10.1002/art.27263

van Rooij, E., Fielitz, J., Sutherland, L. B., Thijssen, V. L., Crijns, H. J., Dimaio, M. J., Shelton, J., De Windt, L. J., Hill, J. A., & Olson, E. N. (2010). Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor. Circulation Research, 106(1), 155-U315. https://doi.org/10.1161/CIRCRESAHA.109.207084

Lenaers, E., Feyter, H. M., Hoeks, J., Schrauwen, P., Schaart, G., Nabben, M., Nicolay, K., Prompers, J. J., & Hesselink, M. K. (2010). Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats.Obesity, 18(6), 1100-1107. https://doi.org/10.1038/oby.2009.372

Jacobs, H., Moalin, M., Bast, A., van der Vijgh, W. J., & Haenen, G. R. M. M. (2010). An essential difference between the flavonoids monoHER and quercetin in their interplay with the endogenous antioxidant network. PLOS ONE, 5(11), Article e13880. https://doi.org/10.1371/journal.pone.0013880

Bartholomé, R., Haenen, G. R. M. M., Hollman, C. H., Bast, A., Dagnelie, P. C., Roos, D., Keijer, J., Kroon, P. A., Needs, P. W., & Arts, C. W. (2010). Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by beta-glucuronidase from Neutrophils. Drug metabolism and pharmacokinetics, 25(4), 379-87. https://doi.org/10.2133/dmpk.DMPK-10-RG-002

den Hartog, G. J., Boots, A. W., Adam Perrot, A., Brouns, F. J. P. H., Verkooijen, I. W., Weseler, A. R., Haenen, G. R., & Bast, A. (2010). Erythritol is a sweet antioxidant. Nutrition, 26(4), 449-458. https://doi.org/10.1016/j.nut.2009.05.004

Gungor, N., Knaapen, A. M., Munnia, A., Peluso, M., Haenen, G. R., Chiu, R. K., Godschalk, R. W., & van Schooten, F. J. (2010). Genotoxic effects of neutrophils and hypochlorous acid. Mutagenesis, 25(2), 149-154. https://doi.org/10.1093/mutage/gep053

Bast, A., Weseler, A. R., Haenen, G. R. M. M., & den Hartog, G. J. M. (2010). Oxidative stress and antioxidants in interstitial lung disease.Current Opinion in Pulmonary Medicine, 16(5), 516-520. https://doi.org/10.1097/MCP.0b013e32833c645d

Wijnen, P. A., Linssen, C. F., Haenen, G. R., Bekers, O., & Drent, M. (2010). Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants. Molecular Diagnosis & Therapy, 14(1), 23-30. https://doi.org/10.1007/BF03256350

Anson, N. M., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2010). Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion. Journal of Cereal Science, 51(1), 110-114. https://doi.org/10.1016/j.jcs.2009.10.005

PROTECT Steering Committee, & Heymans, S. (2010). Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function. Journal of Cardiac Failure, 16(1), 25-35. https://doi.org/10.1016/j.cardfail.2009.10.025

el Azzouzi, H., van Oort, R. J., van der Nagel, R., Sluiter, W., Bergmann, M. W., & De Windt, L. J. (2010). MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload. European journal of heart failure, 12(1), 4-12. https://doi.org/10.1093/eurjhf/hfp165

van den Borne, S. W. M., Diez, J., Blankesteijn, W. M., Verjans, J., Hofstra, L., & Narula, J. (2010). Myocardial remodeling after infarction: the role of myofibroblasts. Nature Reviews Cardiology, 7(1), 30-37. https://doi.org/10.1038/nrcardio.2009.199

Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R.-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516

Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672

Dennert, R., Velthuis, S., Westermann, D., Donker, D. W., Schalla, S., van Suylen, R.-J., & Heymans, S. (2010). Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy. Antiviral Therapy, 15(4), 681-685. https://doi.org/10.3851/IMP1563

de Jongh, R., Dambros, M., Haenen, G. R., den Hartog, G. J., Bast, A., van Kerrebroeck, P. E., & van Koeveringe, G. A. (2009). Partial bladder outlet obstruction reduces the tissue antioxidant capacity and muscle nerve density of the guinea pig bladder. Neurourology and Urodynamics, 28(5), 461-467. https://doi.org/10.1002/nau.20677

Boots, A. W., Drent, M., Swennen, E. L., Moonen, H. J., Bast, A., & Haenen, G. R. (2009). Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants. Respiratory Medicine, 103(3), 364-372. https://doi.org/10.1016/j.rmed.2008.10.007

Boots, A. W., Hristova-Dijkstra, M. J., Kasahara, D. I., Haenen, G. R., Bast, A., & van der Vliet, A. (2009). ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli.Journal of Biological Chemistry, 284(26), 17858-17867. https://doi.org/10.1074/jbc.M809761200

Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. (2009). Bioavailability of ferulic acid is determined by its bioaccessibility. Journal of Cereal Science, 49(2), 296-300. https://doi.org/10.1016/j.jcs.2008.12.001

Mateo Anson, N., Selinheimo, E., Havenaar, R., Aura, A. M., Mattila, I., Lehtinen, P., Bast, A., Poutanen, K., & Haenen, G. R. (2009). Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds.Journal of Agricultural and Food Chemistry, 57(14), 6148-6155. https://doi.org/10.1021/jf900492h

Jacobs, H., van der Vijgh, W. J., Koek, G. H., Draaisma, G. J., Moalin, M., van Strijdonck, G. P., Bast, A., & Haenen, G. R. (2009). Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER. Free Radical Biology and Medicine, 46(12), 1567-1573. https://doi.org/10.1016/j.freeradbiomed.2009.02.031

Balk, J. M., Bast, A., & Haenen, G. R. (2009). Evaluation of the accuracy of antioxidant competition assays: incorrect assumptions with major impact.Free Radical Biology and Medicine, 47(2), 135-144. https://doi.org/10.1016/j.freeradbiomed.2009.04.009

Mateo Anson, N., van den Berg, R., Havenaar, R., Haenen, G. R., & Bast, A. (2008). Antioxidant and anti-inflammatory potency of different wheat varieties and fractions. Proceedings of the Nutrition Society, 67(OCE1), Article E56. https://doi.org/10.1017/S0029665108006654

Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. (2008). Ferulic Acid from Aleurone Determines the Antioxidant Potency of Wheat Grain (Triticum aestivum L.). Journal of Agricultural and Food Chemistry, 56(14), 5589-5594. https://doi.org/10.1021/jf800445k

Boots, A. W., Haenen, G. R., & Bast, A. (2008). Health effects of quercetin: from antioxidant to nutraceutical.European Journal of Pharmacology, 585(2-3), 325-337. https://doi.org/10.1016/j.ejphar.2008.03.008

Boots, A., Wilms, L. C., Swennen, E. L., Kleinjans, J. C., Bast, A., & Haenen, G. R. (2008). In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition, 24(7-8), 703-10. https://doi.org/10.1016/j.nut.2008.03.023

de Jongh, R., Haenen, G. R. M. M., van Koeveringe, G. A., Dambros, M., & van Kerrebroeck, P. E. V. (2008). Lipid peroxidation product 4-hydroxynonenal contributes to bladder smooth muscle damage.Urology, 71(5), 974-978. https://doi.org/10.1016/j.urology.2007.11.014

Hoeks, J., Briede, J. J., de Vogel, J., Schaart, G., Nabben, M., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). Mitochondrial function, content and ROS production in rat skeletal muscle: effect of high-fat feeding. Febs Letters, 582(4), 510-6. https://doi.org/10.1016/j.febslet.2008.01.013

Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008

Rensen, S., Niessen, P. M., van Deursen, J. M., Janssen, B. J., Heijman, E., Hermeling, E., Meens, M. J. P. M. T., Lie, N., Gijbels, M. J., Strijkers, G. J., Doevendans, P. A., Hofker, M. H., de Mey, J. G., & van Eys, G. J. (2008). Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation, 118(8), 828-36. https://doi.org/10.1161/CIRCULATIONAHA.107.743690

Nabben, M., Hoeks, J., Briede, J. J., Glatz, J. F., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. Febs Letters, 582(30), 4147-4152. https://doi.org/10.1016/j.febslet.2008.11.016

Donker, D. W., Maessen, J. G., Verheyen, F., Ramaekers, F., Spätjens, R. L. H., Kuijpers, R., Rarnakers, C., Schiffers, P. M. H., Vos, M. A., Crijns, H. J. G. M., & Volders, P. G. A. (2007). Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. American Journal of Physiology-heart and Circulatory Physiology, 292(5), H2324-H2332. https://doi.org/10.1152/ajpheart.00392.2006

Rezk, B. M., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2007). Alpha-tocopheryl phosphate is a novel apoptotic agent. Frontiers in Bioscience, 12, 2013-2019. https://doi.org/10.2741/2206

Haenen, G. R. M. M., & Bast, A. (2007). Antioxidanten overbodig? Prietpraat!Chemisch2Weekblad, 102(18), 26-27.

Rietjens, S. J., Beelen, M., Koopman, R., van Loon, L. J., Bast, A., & Haenen, G. R. (2007). A single session of resistance exercise induces oxidative damage in untrained men. Medicine and Science in Sports and Exercise, 39(12), 2145-2151. https://doi.org/10.1249/mss.0b013e318157936d

Coleman, M. D., Rimmer, G. S., & Haenen, G. R. (2007). Effects of Lipoic Acid and Dihydrolipoic Acid on Total Erythrocytic Thiols under Conditions of Restricted Glucose in vitro. Basic & Clinical Pharmacology & Toxicology, 100(2), 139-144. https://doi.org/10.1111/j.1742-7843.2006.00025.x

Goossens, G. H., Jocken, J. W., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2007). Endocrine Role of the Renin-Angiotensin System in Human Adipose Tissue and Muscle. Effect of {beta}-Adrenergic Stimulation. Hypertension, 49(3), 542-547. https://doi.org/10.1161/01.HYP.0000256091.55393.92

Wilms, L. C., Boots, A. W., de Boer, V. C., Maas, L. M., Pachen, D. M., Gottschalk, R. W., Ketelslegers, H., Godschalk, R. W., Haenen, G. R., van Schooten, F. J., & Kleinjans, J. C. (2007). Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers. Carcinogenesis, 28(8), 1800-1806. https://doi.org/10.1093/carcin/bgm145

van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka, A. E., Janssen, B. J., van der Velden, J. L., Langen, R. C., Wynshaw Boris, A., Smits, J. F., & Blankesteijn, W. M. (2007). Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension, 49(3), 473-480. https://doi.org/10.1161/01.HYP.0000255946.55091.24