van der Kolk, J. H., Boelens, R., Halkes, S. B. A., Wijnberg, I. D., de Sain-van der Velden, M. G. M., & Ippel, J. H. (2013). Some notes on fatal acquired multiple acyl-CoA dehydrogenase deficiency (MADD) in a two-year-old warmblood stallion and European tar spot (Rhytisma acerinum). Veterinary Quarterly, 33(1), 51-55. https://doi.org/10.1080/01652176.2012.758904

Soehnlein, O., Drechsler, M., Doering, Y., Lievens, D., Hartwig, H., Kemmerich, K., Ortega-Gomez, A., Mandl, M., Vijayan, S., Projahn, D., Garlichs, C. D., Koenen, R. R., Hristov, M., Lutgens, E., Zernecke, A., & Weber, C. (2013). Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO Molecular Medicine, 5(3), 471-481. https://doi.org/10.1002/emmm.201201717

Demirkan, A., Isaacs, A., Ugocsai, P., Liebisch, G., Struchalin, M., Rudan, I., Wilson, J. F., Pramstaller, P. P., Gyllensten, U., Campbell, H., Schmitz, G., Oostra, B. A., & van Duijn, C. M. (2013). Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study. Journal of Psychiatric Research, 47(3), 357-62. https://doi.org/10.1016/j.jpsychires.2012.11.001

Ten Cate-Hoek, A. J., Prins, M. H., Wittens, C. H. A., & Cate, H. T. (2013). Postintervention duration of anticoagulation in venous surgery. Phlebology: The Journal of Venous Disease, 28(1_suppl), 105-111. https://doi.org/10.1177/0268355513476415

Kumar, N., Ippel, H., Weber, C., Hackeng, T., & Mayo, K. H. (2013). Protein lysine-N zeta alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species. Protein Science, 22(3), 327-346. https://doi.org/10.1002/pro.2214

Borissoff, J. I., Otten, J. J. T., Heeneman, S., Leenders, P., van Oerle, R., Soehnlein, O., Loubele, S. T. B. G., Hamulyak, K., Hackeng, T. M., Daemen, M. J. A. P., Degen, J. L., Weiler, H., Esmon, C. T., van Ryn, J., Biessen, E. A. L., Spronk, H. M. H., & ten Cate, H. (2013). Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner. PLOS ONE, 8(2), Article e55784. https://doi.org/10.1371/journal.pone.0055784

Esser, D., Oosterink, E., 't Roodt, J. O., Henry, R. M. A., Stehouwer, C. D. A., Muller, M., & Afman, L. A. (2013). Vascular and Inflammatory High Fat Meal Responses in Young Healthy Men; A Discriminative Role of IL-8 Observed in a Randomized Trial. PLOS ONE, 8(2), Article e53474. https://doi.org/10.1371/journal.pone.0053474

Wijnen, P. A. H. M., Verschakelen, J. A., Bast, A., Bekers, O., & Drent, M. (2013). Diffuse alveolar hemorrhage in coumarin users: a fibrosing interstitial pneumonia trigger?Lung, 191(1), 53-59. https://doi.org/10.1007/s00408-012-9436-2

Bos, D., Ikram, M. A., Isaacs, A., Verhaaren, B. F. J., Hofman, A., van Duijn, C. M., Witteman, J. C. M., van der Lugt, A., & Vernooij, M. W. (2013). Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification. Circulation : Cardiovascular Genetics, 6(1), 47-53. https://doi.org/10.1161/CIRCGENETICS.112.963934

Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'Seaghdha, C. M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, R. P. S., Brown, M. J., ... LifeLines Cohort Study (2013). Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics, 45(2), 145-54. https://doi.org/10.1038/ng.2500

Rademakers, T., Douma, K., Hackeng, T. M., Post, M. J., Sluimer, J. C., Daemen, M. J. A. P., Biessen, E. A. L., Heeneman, S., & van Zandvoort, M. A. M. J. (2013). Plaque-Associated Vasa Vasorum in Aged Apolipoprotein E-Deficient Mice Exhibit Proatherogenic Functional Features In Vivo. Arteriosclerosis Thrombosis and Vascular Biology, 33(2), 249–256. https://doi.org/10.1161/ATVBAHA.112.300087

Westein, E., van der Meer, A. D., Kuijpers, M. J. E., Frimat, J.-P., van den Berg, A., & Heemskerk, J. W. M. (2013). Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner. Proceedings of the National Academy of Sciences of the United States of America, 110(4), 1357-1362. https://doi.org/10.1073/pnas.1209905110

van de Laar, R. J. J., Stehouwer, C. D. A., van Bussel, B. C. T., Prins, M. H., Twisk, J. W., & Ferreira, I. (2013). Adherence to a Mediterranean dietary pattern in early life is associated with lower arterial stiffness in adulthood: the Amsterdam Growth and Health Longitudinal Study.Journal of Internal Medicine, 273(1), 79-93. https://doi.org/10.1111/j.1365-2796.2012.02577.x

Nergiz-Unal, R., Kuijpers, M. J. E., de Witt, S. M., Heeneman, S., Feijge, M. A. H., Garcia Caraballo, S., Biessen, E. A., Haenen, G. R. M. M., Cosemans, J. M., & Heemskerk, J. W. (2013). Atheroprotective effect of dietary walnut intake in ApoE-deficient mice: Involvement of lipids and coagulation factors.Thrombosis Research, 131(5), 411-417. https://doi.org/10.1016/j.thromres.2013.01.003

Wolters, M., Mohades, S. G., Hackeng, T. M., Post, M. J., Kooi, M. E., & Backes, W. H. (2013). Clinical perspectives of hybrid proton-fluorine magnetic resonance imaging and spectroscopy.Investigative Radiology, 48(5), 341-350. https://doi.org/10.1097/RLI.0b013e318277528c

Wolters, M., van Hoof, R. H., Wagenaar, A., Douma, K., van Zandvoort, M. A., Hackeng, T. M., Post, M. J., Backes, W. H., & Kooi, M. E. (2013). MRI artifacts in the ferric chloride thrombus animal model: an alternative solution: preventing MRI artifacts after thrombus induction with a non-ferromagnetic Lewis acid. Journal of Thrombosis and Haemostasis, 11(9), 1766-1769. https://doi.org/10.1111/jth.12340

Baumgartner, S., Mensink, R. P., den Hartog, G. J., Bast, A., Bekers, O., Husche, C., Lutjohann, D., & Plat, J. (2013). Oxyphytosterol formation in humans: Identification of high vs. low oxidizers.Biochemical Pharmacology, 86(1), 19-25. https://doi.org/10.1016/j.bcp.2013.02.035

Smulders, M. W., Kietselaer, B. L. J. H., Das, M., Wildberger, J. E., Crijns, H. J. G. M., Veenstra, L., Brunner La Rocca, H. P., van Dieijen-Visser, M. P., Mingels, A. M. A., Dagnelie, P. C., Post, M. J., Gorgels, A. P. M., van Asselt, A. D. I., Vogel, G., Schalla, S., Kim, R. J., & Bekkers, S. C. A. M. (2013). The role of cardiovascular magnetic resonance imaging and computed tomography angiography in suspected non-ST-elevation myocardial infarction patients: Design and rationale of the CARdiovascular Magnetic rEsoNance imaging and computed Tomography Angiography (CARMENTA) trial. American Heart Journal, 166(6), 968-975. https://doi.org/10.1016/j.ahj.2013.09.012

Knapen, L. M., Dittrich, S. T., de Vries, F., Starup-Linde, J., Vestergaard, P., Henry, R. M. A., Stolk, L. M., Neef, C. K., & Bazelier, M. T. (2013). Use of biguanides and the risk of colorectal cancer: a register-based cohort study. Current Drug Safety, 8(5), 349-356. https://doi.org/10.2174/15680266113136660068

Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimäki, T., Kreiner-Møller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., ... Freathy, R. (2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics, 45(1), 76-82. https://doi.org/10.1038/ng.2477

Heemskerk, J. W. M., Mattheij, N. J. A., & Cosemans, J. M. E. M. (2013). Platelet-based coagulation: different populations, different functions. Journal of Thrombosis and Haemostasis, 11(1), 2-16. https://doi.org/10.1111/jth.12045

Prinzen, L., Staal, H. M., Rouwette, S. J. M., Beckers, E. A. M., ten Broeke, R. H. M., van Rhijn, L. W., & Henskens, Y. M. C. (2013). Triple Red Blood Cell Alloantibody Formation After Bone-Allograft Transplantation. American Journal of Transplantation, 13(1), 229-231. https://doi.org/10.1111/j.1600-6143.2012.04300.x

Vasina, E. M., Cauwenberghs, S., Staudt, M., Feijge, M. A., Weber, C., Koenen, R. R., & Heemskerk, J. W. (2013). Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release. American Journal of Blood Research, 3(2), 107-23. https://pubmed.ncbi.nlm.nih.gov/23675563/

Tijink, M., Janssen, J., Timmer, M., Austen, J., Aldenhoff, Y., Kooman, J., Koole, L., Damoiseaux, J., van Oerle, R., Henskens, Y., & Stamatialis, D. (2013). Development of novel membranes for blood purification therapies based on copolymers of N-vinylpyrrolidone and n-butylmethacrylate. Journal of Materials Chemistry. B, Materials for Biology and Medicine, 1(44), 6066-6077. https://doi.org/10.1039/c3tb20964d

Lance, M. D., Henskens, Y., Nelemans, P., Theunissen, M. H. S., Van Oerle, R., Spronk, H. M., & Marcus, M. A. E. (2013). Do blood collection methods influence whole-blood platelet function analysis?Platelets, 24(4), 275-281. https://doi.org/10.3109/09537104.2012.689038

van der Loos, M. J. H. M., Rietveld, C. A., Eklund, N., Koellinger, P. D., Rivadeneira, F., Abecasis, G. R., Ankra-Badu, G. A., Baumeister, S. E., Benjamin, D. J., Biffar, R., Blankenberg, S., Boomsma, D. I., Cesarini, D., Cucca, F., de Geus, E. J. C., Dedoussis, G., Deloukas, P., Dimitriou, M., Eiriksdottir, G., ... Thurik, A. R. (2013). The molecular genetic architecture of self-employment. PLOS ONE, 8(4), e60542. https://doi.org/10.1371/journal.pone.0060542

Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H. H. M., Ried, J. S., van Zuydam, N. R., Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C. P., ... European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium (2013). The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLOS Medicine , 10(6), e1001474. https://doi.org/10.1371/journal.pmed.1001474

Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M.-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., ... CARDIoGRAM Consortium (2012). Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Human Molecular Genetics, 21(24), 5329-43. https://doi.org/10.1093/hmg/dds369

Borissoff, J. I., Joosen, I. A., Versteylen, M. O., Spronk, H. M., ten Cate, H., & Hofstra, L. (2012). Accelerated In Vivo Thrombin Formation Independently Predicts the Presence and Severity of CT Angiographic Coronary Atherosclerosis. JACC-Cardiovascular Imaging, 5(12), 1201-1210. https://doi.org/10.1016/j.jcmg.2012.01.023

Dargaud, Y., Wolberg, A. S., Luddington, R., Regnault, V., Spronk, H., Baglin, T., Lecompte, T., Ten Cate, H., & Negrier, C. (2012). Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: An international multicentre study. Thrombosis Research, 130(6), 929-934. https://doi.org/10.1016/j.thromres.2012.07.017

Ibrahim-Verbaas, C. A., Zorkoltseva, I. V., Amin, N., Schuur, M., Coppus, A. M. W., Isaacs, A., Aulchenko, Y. S., Breteler, M. M. B., Ikram, M. A., Axenovich, T. I., Verbeek, M. M., van Swieten, J. C., Oostra, B. A., & van Duijn, C. M. (2012). Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2. Human Genetics, 131(12), 1869-76. https://doi.org/10.1007/s00439-012-1210-2

Projahn, D., & Koenen, R. R. (2012). Platelets: key players in vascular inflammation. Journal of Leukocyte Biology, 92(6), 1167-1175. https://doi.org/10.1189/jlb.0312151

Loeffen, R., Kleinegris, M. .-C. F., Loubele, S. T. B. G., Pluijmen, P. H. M., Fens, D., van Oerle, R., ten Cate, H., & Spronk, H. M. H. (2012). Preanalytic variables of thrombin generation: towards a standard procedure and validation of the method. Journal of Thrombosis and Haemostasis, 10(12), 2544-2554. https://doi.org/10.1111/jth.12012

Kroon, M. H., Diamant, M., Van Den Hurk, K., Boomsma, F., Alssema, M., Nijpels, G., Kamp, O., Paulus, W. J., Stehouwer, C. D. A., Dekker, J. M., & Henry, R. M. A. (2012). Prospective Associations of B-Type Natriuretic Peptide With Markers of Left Ventricular Function in Individuals With and Without Type 2 Diabetes An 8-year follow-up of the Hoorn Study. Diabetes Care, 35(12), 2510-2514. https://doi.org/10.2337/dc11-1959

Van de Vijver, P., Schmitt, M., Suylen, D., Scheer, L., Thomassen, M. C. L. G. D., Schurgers, L. J., Griffin, J. H., Koenen, R. R., & Hackeng, T. M. (2012). Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S. Journal of the American Chemical Society, 134(47), 19318-19321. https://doi.org/10.1021/ja306993t

Geenen, I. L., Post, M. J., Molin, D. G. M., Schurink, G. W. H., Maessen, J. G., van Oerle, R., ten Cate, H., & Spronk, H. M. H. (2012). Coagulation on endothelial cells: the underexposed part of Virchow's Triad. Thrombosis and Haemostasis, 108(5), 863-871. https://doi.org/10.1160/TH12-04-0269

Amin, N., Byrne, E., Johnson, J., Chenevix-Trench, G., Walter, S., Nolte, I. M., Vink, J. M., Rawal, R., Mangino, M., Teumer, A., Keers, J. C., Verwoert, G., Baumeister, S., Biffar, R., Petersmann, A., Dahmen, N., Doering, A., Isaacs, A., Broer, L., ... van Duijn, C. M. (2012). Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Molecular Psychiatry, 17(11), 1116-29. https://doi.org/10.1038/mp.2011.101

Nazari-Jahantigh, M., Wei, Y., Noels, H., Akhtar, S., Zhou, Z., Koenen, R. R., Heyll, K., Gremse, F., Kiessling, F., Grommes, J., Weber, C., & Schober, A. (2012). MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. Journal of Clinical Investigation, 122(11), 4190-4202. https://doi.org/10.1172/JCI61716

Willemsen, S., Hartog, J. W. L., van Veldhuisen, D. J., van der Meer, P., Roze, J. F., Jaarsma, T., Schalkwijk, C., van der Horst, I. C. C., Hillege, H. L., & Voors, A. A. (2012). The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction. American Heart Journal, 164(5), 742-U146. https://doi.org/10.1016/j.ahj.2012.07.027

Compeer, M. G., Suylen, D. P. L., Hackeng, T. M., & De Mey, J. G. R. (2012). Endothelin-1 and-2: Two amino acids matter. Life Sciences, 91(13-14), 607-612. https://doi.org/10.1016/j.lfs.2012.02.011

Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Maegi, R., Waite, L. L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., ... Visscher, P. M. (2012). FTO genotype is associated with phenotypic variability of body mass index. Nature, 490(7419), 267–272. https://doi.org/10.1038/nature11401

Geersing, G.-J., Erkens, P. M. G., Lucassen, W. A. M., Buller, H. R., ten Cate, H., Hoes, A. W., Moons, K. G. M., Prins, M. H., Oudega, R., van Weert, H. C. P. M., & Stoffers, H. E. J. H. (2012). Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ, 345(7880), Article e6564. https://doi.org/10.1136/bmj.e6564

Amin, N., Schuur, M., Gusareva, E. S., Isaacs, A., Aulchenko, Y. S., Kirichenko, A. V., Zorkoltseva, I. V., Axenovich, T. I., Oostra, B. A., Janssens, A. C. J. W., & van Duijn, C. M. (2012). A genome-wide linkage study of individuals with high scores on NEO personality traits. Molecular Psychiatry, 17(10), 1031-41. https://doi.org/10.1038/mp.2011.97

Talens, S., Malfliet, J. J. M. C., Rudez, G., Spronk, H. M. H., Janssen, N. A. H., Meijer, P., Kluft, C., de Maat, M. P. M., & Rijken, D. C. (2012). Biological variation in tPA-induced plasma clot lysis time. Thrombosis and Haemostasis, 108(4), 640-646. https://doi.org/10.1160/TH12-02-0124

van der Meijden, P. E. J., Feijge, M. A. H., Swieringa, F., Gilio, K., Nergiz-Unal, R., Hamulyak, K., & Heemskerk, J. W. M. (2012). Key role of integrin alpha(IIb)beta(3) signaling to Syk kinase in tissue factor-induced thrombin generation. Cellular and Molecular Life Sciences, 69(20), 3481-3492. https://doi.org/10.1007/s00018-012-1033-2

Erkens, P. M. G., ten Cate, H., Buller, H. R., & Prins, M. H. (2012). Benchmark for Time in Therapeutic Range in Venous Thromboembolism: A Systematic Review and Meta-Analysis. PLOS ONE, 7(9), Article e42269. https://doi.org/10.1371/journal.pone.0042269

Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, J., Mägi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Sanna, S., Sidore, C., Johnson, P. C. D., Jukema, J. W., ... Barroso, I. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, 44(9), 991-1005. https://doi.org/10.1038/ng.2385

Lance, M. D., Kuiper, G. J. A. J. M., Sloep, M., Spronk, H. M. H., van Oerle, R., ten Cate, H., Marcus, M. A. E., & Henskens, Y. M. C. (2012). The effects of pneumatic tube system transport on ROTEM analysis and contact activation assessed by thrombin generation test. Thrombosis Research, 130(3), E147-E150. https://doi.org/10.1016/j.thromres.2012.05.002

Mingels, A. M., Cobbaert, C. M., de Jong, N., van den Hof, W. F., & van Dieijen-Visser, M. P. (2012). Time- and temperature-dependent stability of troponin standard reference material 2921 in serum and plasma. Clinical Chemistry and Laboratory Medicine, 50(9), 1681-1684. https://doi.org/10.1515/cclm-2011-1851

Marchetti, M., Diani, E., ten Cate, H., & Falanga, A. (2012). Characterization of the thrombin generation potential of leukemic and solid tumor cells by calibrated automated thrombography. Haematologica-the Hematology Journal, 97(8), 1173-1180. https://doi.org/10.3324/haematol.2011.055343