• 2014
    • van Dongen, M., van Kraaij, D., Schalla, S., Brunner-La Rocca, H., & Driessen, R. (2014). Severe mitral regurgitation caused by eosinophilic endocarditis. Journal of Cardiology Cases, 10(3). https://doi.org/10.1016/j.jccase.2014.05.012
    • van Leeuwen, E. M., Smouter, F. A. S., Kam-Thong, T., Karbalai, N., Smith, A. V., Harris, T. B., Launer, L. J., Sitlani, C. M., Li, G., Brody, J. A., Bis, J. C., White, C. C., Jaiswal, A., Oostra, B. A., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Boerwinkle, E., Ballantyne, C. M., ... van Duijn, C. M. (2014). The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels. PLOS ONE, 9(10), e109290. https://doi.org/10.1371/journal.pone.0109290
  • 2013
    • Agten, S. M., Suylen, D., Ippel, H., Kokozidou, M., Tans, G., van de Vijver, P., Koenen, R. R., & Hackeng, T. M. (2013). Chemoselective Oxime Reactions in Proteins and Peptides by Using an Optimized Oxime Strategy: The Demise of Levulinic Acid. Chembiochem, 14(18), 2431-2434. https://doi.org/10.1002/cbic.201300598
    • Reinders, I., van Ballegooijen, A. J., Visser, M., Elshorbagy, A. K., Refsum, H., Henry, R. M. A., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., & Brouwer, I. A. (2013). Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. European Journal of Clinical Nutrition, 67(12), 1277-1283. https://doi.org/10.1038/ejcn.2013.167
    • Manthey, H. D., Cochain, C., Barnsteiner, S., Karshovska, E., Pelisek, J., Koch, M., Chaudhari, S. M., Busch, M., Eckstein, H.-H., Weber, C., Koenen, R. R., & Zernecke, A. (2013). CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice. Thrombosis and Haemostasis, 110(6), 1267-77. https://doi.org/10.1160/TH13-01-0017
    • Parsa, A., Fuchsberger, C., Köttgen, A., O'Seaghdha, C. M., Pattaro, C., de Andrade, M., Chasman, D. I., Teumer, A., Endlich, K., Olden, M., Chen, M.-H., Tin, A., Kim, Y. J., Taliun, D., Li, M., Feitosa, M., Gorski, M., Yang, Q., Hundertmark, C., ... Böger, C. A. (2013). Common variants in Mendelian kidney disease genes and their association with renal function. Journal of the American Society of Nephrology, 24(12), 2105-17. https://doi.org/10.1681/ASN.2012100983
    • Hilhorst, M., Winckers, K., Wilde, B., van Oerle, R., ten Cate, H., & Tervaert, J. W. C. (2013). Patients with Antineutrophil Cytoplasmic Antibodies Associated Vasculitis in Remission Are Hypercoagulable. Journal of Rheumatology, 40(12), 2042-2046. https://doi.org/10.3899/jrheum.130200
    • Nuzzo, F., Radu, C., Baralle, M., Spiezia, L., Hackeng, T. M., Simioni, P., & Castoldi, E. (2013). Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation. Blood, 122(23), 3825-3831. https://doi.org/10.1182/blood-2013-04-499657
    • Nickel, K. F., Spronk, H. M., Mutch, N. J., & Renné, T. (2013). Time-dependent degradation and tissue factor addition mask the ability of platelet polyphosphates in activating factor XII-mediated coagulation. Blood, 122(23), 3847-3849. https://doi.org/10.1182/blood-2013-09-525840
    • Miglianico, M., Oligschläger, Y., Chanda, D., Bleylevens, I., Nicolaes, G., & Neumann, D. (2013). PS6 - 4. Toward selective targeting of muscular AMPK: in search of a small molecule to change AMPK cellular localization. Nederlands Tijdschrift voor Diabetologie, 11(4), 151-151. https://doi.org/10.1007/s12467-013-0092-9
    • Hoefer, I. E., Sels, J.-W., Jukema, J. W., Bergheanu, S., Biessen, E., McClellan, E., Daemen, M., Doevendans, P., de Groot, P., Hillaert, M., Horsman, S., Ilhan, M., Kuiper, J., Pijls, N., Redekop, K., van der Spek, P., Stubbs, A., van de Veer, E., Waltenberger, J., ... Pasterkamp, G. (2013). Circulating cells as predictors of secondary manifestations of cardiovascular disease: design of the CIRCULATING CELLS study. Clinical research in cardiology, 102(11), 847-856. https://doi.org/10.1007/s00392-013-0607-9
    • Do, R., Willer, C. J., Schmidt, E. M., Sengupta, S., Gao, C., Peloso, G. M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., Buchkovich, M. L., Mora, S., Beckmann, J. S., Bragg-Gresham, J. L., Chang, H.-Y., Demirkan, A., Den Hertog, H. M., Donnelly, L. A., Ehret, G. B., ... Author collaboration (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, 45(11), 1345-1352. https://doi.org/10.1038/ng.2795
    • Willer, C. J., Schmidt, E. M., Sengupta, S., Peloso, G. M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., Buchkovich, M. L., Mora, S., Beckmann, J. S., Bragg-Gresham, J. L., Chang, H.-Y., Demirkan, A., Den Hertog, H. M., Do, R., Donnelly, L. A., Ehret, G. B., Esko, T., ... Global Lipids Genetics Consortium (2013). Discovery and refinement of loci associated with lipid levels. Nature Genetics, 45(11), 1274-1283. https://doi.org/10.1038/ng.2797
    • Spronk, H. M. H., Borissoff, J. I., & ten Cate, H. (2013). New Insights into Modulation of Thrombin Formation. Current Atherosclerosis Reports, 15(11), Article 363. https://doi.org/10.1007/s11883-013-0363-3
    • Brouwers, M. C. G. J., Konrad, R. J., van Himbergen, T. M., Isaacs, A., Otokozawa, S., Troutt, J. S., Schaefer, E. J., van Greevenbroek, M. M. J., Stalenhoef, A. F. H., & de Graaf, J. (2013). Plasma proprotein convertase subtilisin kexin type 9 levels are related to markers of cholesterol synthesis in familial combined hyperlipidemia. Nutrition Metabolism and Cardiovascular Diseases, 23(11), 1115-1121. https://doi.org/10.1016/j.numecd.2012.11.008
    • Van der Hulle, T., Den Exter, P. L., Erkens, P. G. M., Van Es, J., Mos, I. C. M., Ten Cate, H., Kamphuisen, P. W., Hovens, M. M. C., Buller, H. R., Klok, F. A., & Huisman, M. V. (2013). Variable D-dimer thresholds for diagnosis of clinically suspected acute pulmonary embolism. Journal of Thrombosis and Haemostasis, 11(11), 1986-1992. https://doi.org/10.1111/jth.12394
    • Kramp, B. K., Megens, R. T. A., Sarabi, A., Winkler, S., Projahn, D., Weber, C., Koenen, R. R., & von Hundelshausen, P. (2013). Exchange of extracellular domains of CCR1 and CCR5 reveals confined functions in CCL5-mediated cell recruitment. Thrombosis and Haemostasis, 110(4), 795-806. https://doi.org/10.1160/TH13-05-0420
    • Broer, L., Codd, V., Nyholt, D. R., Deelen, J., Mangino, M., Willemsen, G., Albrecht, E., Amin, N., Beekman, M., de Geus, E. J. C., Henders, A., Nelson, C. P., Steves, C. J., Wright, M. J., de Craen, A. J. M., Isaacs, A., Matthews, M., Moayyeri, A., Montgomery, G. W., ... Boomsma, D. I. (2013). Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. European Journal of Human Genetics, 21(10), 1163-8. https://doi.org/10.1038/ejhg.2012.303
    • Omarova, F., De Willige, S. U., Ariens, R. A. S., Rosing, J., Bertina, R. M., & Castoldi, E. (2013). Inhibition of thrombin-mediated factor V activation contributes to the anticoagulant activity of fibrinogen gamma '. Journal of Thrombosis and Haemostasis, 11(9), 1669-1678. https://doi.org/10.1111/jth.12354
    • Isaacs, A., Willems, S. M., Bos, D., Dehghan, A., Hofman, A., Ikram, M. A., Uitterlinden, A. G., Oostra, B. A., Franco, O. H., Witteman, J. C., & van Duijn, C. M. (2013). Risk scores of common genetic variants for lipid levels influence atherosclerosis and incident coronary heart disease. Arteriosclerosis Thrombosis and Vascular Biology, 33(9), 2233-9. https://doi.org/10.1161/ATVBAHA.113.301236
    • Konings, J., Cugno, M., Suffritti, C., ten Cate, H., Cicardi, M., & Govers-Riemslag, J. W. P. (2013). Ongoing Contact Activation in Patients with Hereditary Angioedema. PLOS ONE, 8(8), Article e74043. https://doi.org/10.1371/journal.pone.0074043
    • Kleinegris, M.-C. F., ten Cate, H., & ten Cate-Hoek, A. J. (2013). D-dimer as a marker for cardiovascular and arterial thrombotic events in patients with peripheral arterial disease A systematic review. Thrombosis and Haemostasis, 110(2), 233-243. https://doi.org/10.1160/TH13-01-0032
    • Borissoff, J. I., Joosen, I. A., Versteylen, M. O., Brill, A., Fuchs, T. A., Savchenko, A. S., Gallant, M., Martinod, K., ten Cate, H., Hofstra, L., Crijns, H. J., Wagner, D. D., & Kietselaer, B. L. J. H. (2013). Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State. Arteriosclerosis Thrombosis and Vascular Biology, 33(8), 2032-2040. https://doi.org/10.1161/ATVBAHA.113.301627
    • Heeb, M. J., Mesters, R. M., Fernandez, J. A., Hackeng, T. M., Nakasone, R. K., & Griffin, J. H. (2013). Plasma protein S residues 37-50 mediate its binding to factor Va and inhibition of blood coagulation. Thrombosis and Haemostasis, 110(2), 275-282. https://doi.org/10.1160/TH12-12-0953
    • Amin, N., Hottenga, J.-J., Hansell, N. K., Janssens, A. C. J. W., de Moor, M. H. M., Madden, P. A. F., Zorkoltseva, I. V., Penninx, B. W., Terracciano, A., Uda, M., Tanaka, T., Esko, T., Realo, A., Ferrucci, L., Luciano, M., Davies, G., Metspalu, A., Abecasis, G. R., Deary, I. J., ... van Duijn, C. M. (2013). Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. European Journal of Human Genetics, 21(8), 876-82. https://doi.org/10.1038/ejhg.2012.263
    • van Bussel, B. C. T., Soedamah Muthu, S. S., Henry, R. M., Schalkwijk, C. G., Ferreira, I., Chaturvedi, N., Toeller, M., Fuller, J. H., & Stehouwer, C. D. A. (2013). Unhealthy dietary patterns associated with inflammation and endothelial dysfunction in type 1 diabetes: The EURODIAB study. Nutrition Metabolism and Cardiovascular Diseases, 23(8), 758-764. https://doi.org/10.1016/j.numecd.2012.04.005
    • Schuijt, T. J., Bakhtiari, K., Daffre, S., DePonte, K., Wielders, S. J. H., Marquart, J. A., Hovius, J. W., van der Poll, T., Fikrig, E., Bunce, M. W., Camire, R. M., Nicolaes, G. A. F., Meijers, J. C. M., & van 't Veer, C. (2013). Factor Xa Activation of Factor V Is of Paramount Importance in Initiating the Coagulation System: Lessons From a Tick Salivary Protein. Circulation, 128(3), 254-266. https://doi.org/10.1161/CIRCULATIONAHA.113.003191
    • Cosemans, J. M. E. M., Angelillo-Scherrer, A., Mattheij, N. J. A., & Heemskerk, J. W. M. (2013). The effects of arterial flow on platelet activation, thrombus growth, and stabilization. Cardiovascular Research, 99(2), 342-352. https://doi.org/10.1093/cvr/cvt110
    • Konings, J., Govers-Riemslag, J. W. P., Spronk, H. M. H., Waltenberger, J. L., & ten Cate, H. (2013). Activation of the contact system in patients with a first acute myocardial infarction. Thrombosis Research, 132(1), 138-142. https://doi.org/10.1016/j.thromres.2013.05.016
    • Panova-Noeva, M., Marchetti, M., Russo, L., Tartari, C. J., Leuzzi, A., Finazzi, G., Rambaldi, A., ten Cate, H., & Falanga, A. (2013). ADP-induced platelet aggregation and thrombin generation are increased in Essential Thrombocythemia and Polycythemia Vera. Thrombosis Research, 132(1), 88-93. https://doi.org/10.1016/j.thromres.2013.05.003
    • Eijgenraam, P., ten Cate, H., & ten Cate-Hoek, A. (2013). Safety and Efficacy of Bridging with Low Molecular Weight Heparins: A Systematic Review and Partial Meta-Analysis. Current Pharmaceutical Design, 19(22), 4014-4023. https://doi.org/10.2174/1381612811319220010
    • Cardinaels, E. P. M., Mingels, A. M. A., van Rooij, T., Collinson, P. O., Prinzen, F. W., & van Dieijen-Visser, M. P. (2013). Time-Dependent Degradation Pattern of Cardiac Troponin T Following Myocardial Infarction. Clinical Chemistry, 59(7), 1083-1090. https://doi.org/10.1373/clinchem.2012.200543
    • Smid, M., Dielis, A. W. J. H., Spronk, H. M. H., Rumley, A., van Oerle, R., Woodward, M., ten Cate, H., & Lowe, G. (2013). Thrombin Generation in the Glasgow Myocardial Infarction Study. PLOS ONE, 8(6), Article e66977. https://doi.org/10.1371/journal.pone.0066977
    • Dijkgraaf, I., Van de Vijver, P., Dirksen, A., & Hackeng, T. M. (2013). Synthesis and application of cNGR-containing imaging agents for detection of angiogenesis. Bioorganic & Medicinal Chemistry, 21(12), 3555-3564. https://doi.org/10.1016/j.bmc.2013.04.002
    • Bosch, Y., Al Dieri, R., Ten Cate, H., Nelemans, P., Bloemen, S., Hemker, C., Weerwind, P., Maessen, J., & Mochtar, B. (2013). Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article. Journal of Cardiothoracic Surgery, 8(1). https://doi.org/10.1186/1749-8090-8-154
    • Theuwissen, E., Teunissen, K. J., Spronk, H. M. H., Hamulyak, K., Ten Cate, H., Shearer, M. J., Vermeer, C., & Schurgers, L. J. (2013). Effect of low-dose supplements of menaquinone-7 (vitamin K-2) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers. Journal of Thrombosis and Haemostasis, 11(6), 1085-1092. https://doi.org/10.1111/jth.12203
    • den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H.-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., ... Loos, R. J. F. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, 45(6), 621-31. https://doi.org/10.1038/ng.2610
    • van der Meijden, P. E. J., Bouman, A. C., Feijge, M. A. H., van Oerle, R., Spronk, H. M. H., Hamulyak, K., ten Cate-Hoek, A. J., ten Cate, H., & Heemskerk, J. W. M. (2013). Platelet Dysfunction in Thrombosis Patients Treated with Vitamin K Antagonists and Recurrent Bleeding. PLOS ONE, 8(5). https://doi.org/10.1371/journal.pone.0064112
    • Grottke, O., Rossaint, R., Henskens, Y., van Oerle, R., ten Cate, H., & Spronk, H. H. (2013). Thrombin Generation Capacity of Prothrombin Complex Concentrate in an In Vitro Dilutional Model. PLOS ONE, 8(5), Article e64100. https://doi.org/10.1371/journal.pone.0064100
    • Mattheij, N. J. A., Gilio, K., van Kruchten, R., Jobe, S. M., Wieschhaus, A. J., Chishti, A. H., Collins, P., Heemskerk, J. W. M., & Cosemans, J. M. E. M. (2013). Dual Mechanism of Integrin alpha(IIb)beta(3) Closure in Procoagulant Platelets. Journal of Biological Chemistry, 288(19), 13325-13336. https://doi.org/10.1074/jbc.M112.428359
    • Strak, M., Hoek, G., Steenhof, M., Kilinc, E., Godri, K. J., Gosens, I., Mudway, I. S., van Oerle, R., Spronk, H. M. H., Cassee, F. R., Kelly, F. J., Harrison, R. M., Brunekreef, B., Lebret, E., & Janssen, N. A. H. (2013). Components of ambient air pollution affect thrombin generation in healthy humans: the RAPTES project. Occupational and Environmental Medicine, 70(5), 332-340. https://doi.org/10.1136/oemed-2012-100992
    • Raps, M., Rosendaal, F., Ballieux, B., Rosing, J., Thomassen, S., Helmerhorst, F., & Van Vliet, H. (2013). Resistance to APC and SHBG levels during use of a four-phasic oral contraceptive containing dienogest and estradiol valerate: a randomized controlled trial. Journal of Thrombosis and Haemostasis, 11(5), 855-861. https://doi.org/10.1111/jth.12172
    • Winckers, K., ten Cate, H., & Hackeng, T. M. (2013). The role of tissue factor pathway inhibitor in atherosclerosis and arterial thrombosis. Blood Reviews, 27(3), 119-132. https://doi.org/10.1016/j.blre.2013.03.001
    • CARDIOGRAM, METASTROKE, Keating, B. J., & Asselbergs, F. W. (2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics, 22(8), 1663-78. https://doi.org/10.1093/hmg/dds555
    • Peraramelli, S., Thomassen, S., Heinzmann, A., Rosing, J., Hackeng, T. M., Hartmann, R., Scheiflinger, F., & Dockal, M. (2013). Direct inhibition of factor VIIa by TFPI and TFPI constructs. Journal of Thrombosis and Haemostasis, 11(4), 704-714. https://doi.org/10.1111/jth.12152
    • Fuchs, B., de Witt, S., Solecka, B. A., Kroening, M., Obser, T., Cosemans, J. M. E. M., Schneppenheim, R., Heemskerk, J. W. M., & Kannicht, C. (2013). Distinct Role of von Willebrand Factor Triplet Bands in Glycoprotein Ib-Dependent Platelet Adhesion and Thrombus Formation under Flow. Seminars in Thrombosis and Hemostasis, 39(3), 306-314. https://doi.org/10.1055/s-0032-1328971
    • Seehase, M., Houthuizen, P., Jellema, R. K., Collins, J. J., Bekers, O., Breuer, J., & Kramer, B. W. (2013). Propofol administration to the fetal-maternal unit reduces cardiac injury in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest. Pediatric Research, 73(4), 427-434. https://doi.org/10.1038/pr.2013.10
    • Strak, M., Hoek, G., Godri, K. J., Gosens, I., Mudway, I. S., van Oerle, R., Spronk, H. M. H., Cassee, F. R., Lebret, E., Kelly, F. J., Harrison, R. M., Brunekreef, B., Steenhof, M., & Janssen, N. A. H. (2013). Composition of PM Affects Acute Vascular Inflammatory and Coagulative Markers - The RAPTES Project. PLOS ONE, 8(3), Article e58944. https://doi.org/10.1371/journal.pone.0058944
    • van Bussel, B. C. T., Ferreira, I., van de Waarenburg, M. P., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Henry, R. M., Feskens, E. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2013). Multiple inflammatory biomarker detection in a prospective cohort study: a cross-validation between well-established single-biomarker techniques and an electrochemiluminescense-based multi-array platform.PLOS ONE, 8(3), Article 58576. https://doi.org/10.1371/journal.pone.0058576
    • Wantha, S., Alard, J.-E., Megens, R. T. A., van der Does, A. M., Doering, Y., Drechsler, M., Pham, C. T. N., Wang, M.-W., Wang, J.-M., Gallo, R. L., von Hundelshausen, P., Lindbom, L., Hackeng, T., Weber, C., & Soehnlein, O. (2013). Neutrophil-Derived Cathelicidin Promotes Adhesion of Classical Monocytes. Circulation Research, 112(5), 792-801. https://doi.org/10.1161/CIRCRESAHA.112.300666