Harry Crijns

Professor

Harry Crijns is professor and chair of Cardiology and board member of the Cardiovascular Research Institute Maastricht (CARIM) at Maastricht UMC+. He studied medicine at the University of Amsterdam and was trained in cardiology and electrophysiology in Groningen and Maastricht. He is a Fellow of the ESC and a past board member of the EHRA. He is also past Chair of the Netherlands Society of Cardiology. He served on several guidelines committees for the management of AF. Currently he is the chairman of the scientific advisory board of the Dutch Heart Foundation.

His primary research focus continues to be atrial fibrillation (AF). He founded the RACE trials in the Netherlands and led the Euro Heart Survey on AF (ESC). He has established his reputation by introducing innovative concepts for diagnosis and treatment of AF by showing that - quite contrary to longstanding beliefs - electrical management does not change prognosis. This revolutionised management of the arrhythmia worldwide with the effect that major interventions like electrical cardioversion, catheter ablation and antiarrhythmic drug therapy are applied in a much more personalized fashion.

Subsequently his group showed that rate control in AF can be individualized thereby removing the previously used strict heart rate targets from the international guidelines. He also performed the Euro Heart Survey on AF and made many contributions to the field of stroke management in AF, such as the construction of well-recognised AF specific risk stratification scores for AF progression (HATCH), ischemic stroke (CHA2DS2-VASc) and major bleeding (HAS-BLED). These scores have practically conquered the medical AF community and improved patient care whilst boosting new clinical research throughout the world.

His research group now focusses on recent-onset AF, hybrid AF ablation, upstream therapy and vascular mechanisms for AF progression and stroke in idiopathic atrial fibrillation. He is (co-)author on over 650 scientific articles, with 56,677 citations and Hirsch-index of 100.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht


  • 2020
    • Linz, D., & Crijns, H. J. G. M. (2020). Alcohol Abstinence in Drinkers with Atrial Fibrillation. New England Journal of Medicine, 382(18), 1768-1768. https://doi.org/10.1056/NEJMc2001512
    • d'Alessandro, E., Becker, C., Bergmeier, W., Bode, C., Bourne, J. H., Brown, H., Buller, H. R., ten Cate-Hoek, A. J., ten Cate, V., van Cauteren, Y. J. M., Cheung, Y. F. H., Cleuren, A., Coenen, D., Crijns, H. J. G. M., de Simone, I., Dolleman, S. C., Klein, C. E., Fernandez, D. I., Granneman, L., ... Scientific Reviewer Committee (2020). Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 120(4), 538-564. https://doi.org/10.1055/s-0040-1708035
    • De With, R. R., Marcos, E. G., Dudink, E. A. M. P., Spronk, H. M., Crijns, H. J. G. M., Rienstra, M., & Van Gelder, I. C. (2020). Atrial fibrillation progression risk factors and associated cardiovascular outcome in well-phenotyped patients: data from the AF-RISK study. EP Europace, 22(3), 352-360. https://doi.org/10.1093/europace/euz339
    • Wijtvliet, E. P. J. P., Tieleman, R. G., van Gelder, I. C., Pluymaekers, N. A. H. A., Rienstra, M., Folkeringa, R. J., Bronzwaer, P., Elvan, A., Elders, J., Tukkie, R., Luermans, J. G. L. M., Van Asselt, A. D. I. T., Van Kuijk, S. M. J., Tijssen, J. G., Crijns, H. J. G. M., & RACE 4 Investigators (2020). Nurse-led vs. usual-care for atrial fibrillation. European Heart Journal, 41(5), 634-641. https://doi.org/10.1093/eurheartj/ehz666
    • Adriaans, B. P., Westenberg, J. J. M., van Cauteren, Y. J. M., Gerretsen, S., Elbaz, M. S. M., Bekkers, S. C. A. M., Veenstra, L. F., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2020). Clinical assessment of aortic valve stenosis: Comparison between 4D flow MRI and transthoracic echocardiography. Journal of Magnetic Resonance Imaging, 51(2), 472-480. https://doi.org/10.1002/jmri.26847
    • Montalescot, G., Brotons, C., Cosyns, B., Crijns, H. J., D'Angelo, A., Drouet, L., Eberli, F., Lane, D. A., Besse, B., Chan, A., Vicaut, E., Darius, H., & AEGEAN Study Investigators (2020). Educational Impact on Apixaban Adherence in Atrial Fibrillation (the AEGEAN STUDY): A Randomized Clinical Trial. American Journal of Cardiovascular Drugs, 20(1), 61-71. https://doi.org/10.1007/s40256-019-00356-2
    • van Stipdonk, A. M. W., Hoogland, R., Ter Horst, I., Kloosterman, M., Vanbelle, S., Crijns, H. J. G. M., Prinzen, F. W., Meine, M., Maass, A. H., & Vernooy, K. (2020). Evaluating Electrocardiography-Based Identification of Cardiac Resynchronization Therapy Responders Beyond Current Left Bundle Branch Block Definitions. JACC: Clinical Electrophysiology, 6(2), 193-203. https://doi.org/10.1016/j.jacep.2019.10.009
    • Tilz, R. R., Dagres, N., Arbelo, E., Blomstroem-Lundqvist, C., Crijns, H. J., Kirchhof, P., Kautzner, J., Temporelli, P. L., Laroche, C., Roberts, P. R., Pehrson, S., Lip, G. Y. H., Brugada, J., Tavazzi, L., & Atrial Fibrillation Ablation and Atrial Fibrillation Registries Investigators Groups (2020). Which patients with atrial fibrillation undergo an ablation procedure today in Europe? A report from the ESC-EHRA-EORP Atrial Fibrillation Ablation Long-Term and Atrial Fibrillation General Pilot Registries. EP Europace, 22(2), 250-258. https://doi.org/10.1093/europace/euz291
    • Vroomen, M., Maesen, B., Luermans, J. L., Maessen, J. G., Crijns, H. J., La Meir, M., & Pison, L. (2020). Epicardial and Endocardial Validation of Conduction Block After Thoracoscopic Epicardial Ablation of Atrial Fibrillation. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 15(6), 525-531. https://doi.org/10.1177/1556984520956314
    • Pluymaekers, N. A. H. A., Hermans, A. N. L., Linz, D. K., Dudink, E. A. M. P., Luermans, J. G. L. M., Weijs, B., Vernooy, K., & Crijns, H. J. G. M. (2020). Frequency and Determinants of Spontaneous Conversion to Sinus Rhythm in Patients Presenting to the Emergency Department with Recent-onset Atrial Fibrillation: A Systematic Review. Arrhythmia & Electrophysiology Review, 9(4), 195-201. https://doi.org/10.15420/aer.2020.34
  • 2019
    • Pluymaekers, N. A. H. A., Hermans, A. N. L., Middeldorp, M. E., Kadhim, K., Crijns, H. J. G. M., Sanders, P., & Linz, D. (2019). Gender differences and daily variation in atrial fibrillation risk factor profiles: Considerations for risk factor management. IJC Heart and Vasculature, 25, Article 100442. https://doi.org/10.1016/j.ijcha.2019.100442
    • Hendriks, J. M. L., Tieleman, R. G., Vrijhoef, H. J. M., Wijtvliet, P., Gallagher, C., Prins, M. H., Sanders, P., & Crijns, H. J. G. M. (2019). Integrated specialized atrial fibrillation clinics reduce all-cause mortality: post hoc analysis of a randomized clinical trial. EP Europace, 21(12), 1785-1792. https://doi.org/10.1093/europace/euz209
    • Schnabel, R. B., Haeusler, K. G., Healey, J. S., Freedman, B., Boriani, G., Brachmann, J., Brandes, A., Bustamante, A., Casadei, B., Crijns, H. J. G. M., Doehner, W., Engstrom, G., Fauchier, L., Friberg, L., Gladstone, D. J., Glotzer, T. V., Goto, S., Hankey, G. J., Harbison, J. A., ... Yan, B. (2019). Searching for Atrial Fibrillation Poststroke A White Paper of the AF-SCREEN International Collaboration. Circulation, 140(22), 1834-1850. https://doi.org/10.1161/CIRCULATIONAHA.119.040267
    • Smulders, M. W., Kietselaer, B. L. J. H., Wildberger, J. E., Dagnelie, P. C., Brunner-La Rocca, H.-P., Mingels, A. M. A., van Cauteren, Y. J. M., Theunissen, R. A. L. J., Post, M. J., Schalla, S., van Kuijk, S. M. J., Das, M., Kim, R. J., Crijns, H. J. G. M., & Bekkers, S. C. A. M. (2019). Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 74(20), 2466-2477. https://doi.org/10.1016/j.jacc.2019.09.027
    • Yorgun, H., Canpolat, U., Oksul, M., Sener, Y. Z., Ates, A. H., Crijns, H. J. G. M., & Aytemir, K. (2019). Long-term outcomes of cryoballoon-based left atrial appendage isolation in addition to pulmonary vein isolation in persistent atrial fibrillation. EP Europace, 21(11), 1653-1662. https://doi.org/10.1093/europace/euz232
    • Habib, G., Erba, P. A., Iung, B., Donal, E., Cosyns, B., Laroche, C., Popescu, B. A., Prendergast, B., Tornos, P., Sadeghpour, A., Oliver, L., Vaskelyte, J.-J., Sow, R., Axler, O., Maggioni, A. P., Lancellotti, P., Granada, Mahia, M., Ressi, S., ... EURO-ENDO Investigators (2019). Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European infective endocarditis) registry: a prospective cohort study. European Heart Journal, 40(39), 3222-3232B. https://doi.org/10.1093/eurheartj/ehz620
    • Weijs, B., Dudink, E. A. M. P., de Vos, C. B., Limantoro, I., Tieleman, R. G., Pisters, R., Cheriex, E. C., Luermans, J. G. L. M., & Crijns, H. J. G. M. (2019). Idiopathic atrial fibrillation patients rapidly outgrow their low thromboembolic risk: a 10-year follow-up study. Netherlands Heart Journal, 27(10), 487-497. https://doi.org/10.1007/s12471-019-1272-z
    • Sutanto, H., Laudy, L., Clerx, M., Dobrev, D., Crijns, H. J. G. M., & Heijman, J. (2019). Maastricht antiarrhythmic drug evaluator (MANTA): a computational tool for better understanding of antiarrhythmic drugs. Pharmacological Research, 148, Article 104444. https://doi.org/10.1016/j.phrs.2019.104444
    • Kloosterman, M., Crijns, H. J. G. M., & Van Gelder, I. C. (2019). Rising prevalence of atrial fibrillation in the elderly population: new challenges of geriatric cardiology. EP Europace, 21(10), 1451-1453. https://doi.org/10.1093/europace/euz234
    • Lankveld, T. A. R., Vernooy, K., Crijns, H. J. G. M., & Linz, D. (2019). How to make catheter ablation available world-wide?IJC Heart and Vasculature, 24, Article 100411. https://doi.org/10.1016/j.ijcha.2019.100411
    • van der Heijden, C. A. J., Vroomen, M., Luermans, J. G., Vos, R., Crijns, H. J. G. M., Gelsomino, S., La Meir, M., Pison, L., & Maesen, B. (2019). Hybrid versus catheter ablation in patients with persistent and longstanding persistent atrial fibrillation: a systematic review and meta-analysis. European Journal of Cardio-Thoracic Surgery, 56(3), 433-443. https://doi.org/10.1093/ejcts/ezy475
    • den Uijl, D. W., Crijns, H. J. G. M., Vernooy, K., & Linz, D. (2019). Hypnotic communication during atrial fibrillation ablation: Another clinical application of hypnotherapy?IJC Heart and Vasculature, 24, Article 100408. https://doi.org/10.1016/j.ijcha.2019.100408
    • Linz, D., Baumert, M., Desteghe, L., Kadhim, K., Vernooy, K., Kalman, J. M., Dobrev, D., Arzt, M., Sastry, M., Crijns, H. J. G. M., Schotten, U., Cowie, M. R., McEvoy, R. D., Heidbuchel, H., Hendriks, J., Sanders, P., & Lau, D. H. (2019). Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring. IJC Heart and Vasculature, 24, 1-7. Article 100424. https://doi.org/10.1016/j.ijcha.2019.100424
    • Pluymaekers, N. A. H. A., Dudink, E. A. M. P., & Crijns, H. J. G. M. (2019). Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation. New England Journal of Medicine, 381(4), 387-388. https://doi.org/10.1056/NEJMc1906729
    • Habib, G., Lancellotti, P., Erba, P.-A., Sadeghpour, A., Meshaal, M., Sambola, A., Furnaz, S., Citro, R., Ternacle, J., Donal, E., Cosyns, B., Popescu, B., Iung, B., Prendergast, B., Laroche, C., Tornos, P., Pazdernik, M., Maggioni, A., Gale, C. P., ... EURO-ENDO Investigators (2019). The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry. European heart journal - Quality of care & clinical outcomes, 5(3), 202-207. https://doi.org/10.1093/ehjqcco/qcz018
    • Goette, A., Auricchio, A., Boriani, G., Braunschweig, F., Brugada Terradellas, J., Burri, H., Camm, A. J., Crijns, H., Dagres, N., Deharo, J.-C., Dobrev, D., Hatala, R., Hindricks, G., Hohnloser, S. H., Leclercq, C., Lewalter, T., Lip, G. Y. H., Luis Merino, J., Mont, L., ... ESC Scientific Document Group (2019). EHRA White Paper: knowledge gaps in arrhythmia management-status 2019. EP Europace, 21(7), 993-994. https://doi.org/10.1093/europace/euz055
    • Wolf, M., El Haddad, M., De Wilde, V., Phlips, T., De Pooter, J., Almorad, A., Strisciuglio, T., Vandekerckhove, Y., Tavernier, R., Crijns, H. J., Knecht, S., & Duytschaever, M. (2019). Endoscopic evaluation of the esophagus after catheter ablation of atrial fibrillation using contiguous and optimized radiofrequency applications. Heart Rhythm, 16(7), 1013-1020. https://doi.org/10.1016/j.hrthm.2019.01.030
    • Vroomen, M., Olsthoorn, J. R., Maesen, B., L'Espoir, V., La Meir, M., Das, M., Maessen, J. G., Crijns, H. J. G. M., Verheule, S., & Pison, L. (2019). Quantification of epicardial adipose tissue in patients undergoing hybrid ablation for atrial fibrillation. European Journal of Cardio-Thoracic Surgery, 56(1), 79-86. https://doi.org/10.1093/ejcts/ezy472
    • Nguyen, U. C., & Crijns, H. J. G. M. (2019). Undersensing, asynchronous pacing, and ventricular fibrillation. EP Europace, 21(7), 1078. https://doi.org/10.1093/europace/euz009
    • Vroomen, M., La Meir, M., Maesen, B., Luermans, J. G. L., Vernooy, K., Essers, B., de Greef, B. T. A., Maessen, J. G., Crijns, H. J., & Pison, L. (2019). Hybrid thoracoscopic surgical and transvenous catheter ablation versus transvenous catheter ablation in persistent and longstanding persistent atrial fibrillation (HARTCAP-AF): study protocol for a randomized trial. Trials, 20(1), Article 370. https://doi.org/10.1186/s13063-019-3365-9
    • Gulpen, A. J. W., ten Cate, H., Henskens, Y. M. C., van Oerle, R., Wetzels, R., Schalla, S., Crijns, H. J., & ten Cate-Hoek, A. J. (2019). The daily practice of direct oral anticoagulant use in patients with atrial fibrillation; an observational cohort study. PLOS ONE, 14(6), Article 0217302. https://doi.org/10.1371/journal.pone.0217302
    • Vroomen, M., Maesen, B., La Meir, M., Luermans, J. G. L., Vernooy, K., Maessen, J. G., Crijns, H. J., & Pison, L. (2019). Hybrid Ablation of Ventricular Tachycardia: a Single-Centre Experience. Journal of Atrial Fibrillation, 11(5), Article 2118. https://doi.org/10.4022/jafib.2118
    • Chua, W., Easter, C. L., Guasch, E., Sitch, A., Casadei, B., Crijns, H. J. G. M., Haase, D., Hatem, S., Kaab, S., Mont, L., Schotten, U., Sinner, M. F., Hemming, K., Deeks, J. J., Kirchhof, P., & Fabritz, L. (2019). Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset. BMC Cardiovascular disorders, 19(1), Article 120. https://doi.org/10.1186/s12872-019-1105-4
    • Temporelli, P. L., Tilz, R. R., Arbelo, E., Dagres, N., Laroche, C., Crijns, H. J., Blomstrom-Lundqvist, C., Kirchhof, P., Lip, G. Y. H., Boriani, G., Pokushalov, E., Nakou, E., Brugada, J., & Tavazzi, L. (2019). Clinical characteristics of heart failure patients undergoing atrial fibrillation ablation today in Europe. Data from the atrial fibrillation registries of the European Society of Cardiology and the European Heart Rhythm Association. European journal of heart failure, 21(5), 690-693. https://doi.org/10.1002/ejhf.1458
    • Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Luermans, J. G. L. M., Meeder, J. G., Lenderink, T., Widdershoven, J., Bucx, J. J. J., Rienstra, M., Kamp, O., Van Opstal, J. M., Alings, M., Oomen, A., Kirchhof, C. J., Van Dijk, V. F., Ramanna, H., Liem, A., Dekker, L. R., Essers, B. A. B., Tijssen, J. G. P., ... RACE 7 ACWAS Investigators (2019). Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation. New England Journal of Medicine, 380(16), 1499-1508. https://doi.org/10.1056/NEJMoa1900353
    • Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., Beishuizen, A., Stoel, M., ... van Royen, N. (2019). Coronary Angiography after Cardiac Arrest without ST-Segment Elevation. New England Journal of Medicine, 380(15), 1397-1407. https://doi.org/10.1056/NEJMoa1816897
    • van Stipdonk, A. M. W., ter Horst, I., Kloosterman, M., Engels, E. B., Rienstra, M., Crijns, H. J. G. M., Vos, M. A., van Gelder, I. C., Prinzen, F. W., Meine, M., Maass, A., & Vernooy, K. (2019). Response to Letter From Vereckei Regarding, "QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy". Circulation-Arrhythmia and Electrophysiology, 12(4), Article 007297. https://doi.org/10.1161/CIRCEP.119.007297
    • De With, R. R., Rienstra, M., Smit, M. D., Weijs, B., Zwartkruis, V. W., Hobbelt, A. H., Atings, M., Tijssen, J. G. P., Brugemann, J., Geelhoed, B., Hillege, H. L., Tukkie, R., Hemels, M. E., Tieleman, R. G., Ranchor, A., Van Veldhuisen, D. J., Crijns, H. J. G. M., Van Gelder, I. C., & RACE 3 Investigators (2019). Targeted therapy of underlying conditions improves quality of life in patients with persistent atrial fibrillation: results of the RACE 3 study. EP Europace, 21(4), 563-571. https://doi.org/10.1093/europace/euy311
    • Maesen, B., Crijns, H., & La Meir, M. (2019). Letter by Maesen et al Regarding Article, "Randomized Controlled Trial of Surgical Versus Catheter Ablation for Paroxysmal and Early Persistent Atrial Fibrillation". Circulation-Arrhythmia and Electrophysiology, 12(3), Article 007088. https://doi.org/10.1161/CIRCEP.118.007088
    • Lip, G. Y. H., Collet, J.-P., Haude, M., Byrne, R., Chung, E. H., Fauchier, L., Halvorsen, S., Lau, D., Lopez-Cabanillas, N., Lettino, M., Marin, F., Obel, I., Rubboli, A., Storey, R. F., Valgimigli, M., Huber, K., Potpara, T., Lundqvist, C. B., Crijns, H., ... ESC Scientific Document Group (2019). 2018 Joint European consensus document on the management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous cardiovascular interventions: a joint consensus document of the European Heart Rhythm Association (EHRA), European Society of Cardiology Working Group on Thrombosis, European Association of Percutaneous Cardiovascular Interventions (EAPCI). EP Europace, 21(2), 192-193. https://doi.org/10.1093/europace/euy174
    • Lieve, K. V. V., Verhagen, J. M. A., Wei, J., Bos, J. M., van der Werf, C., Roses i Noguer, F., Mancini, G. M. S., Guo, W., Wang, R., van den Heuvel, F., Frohn-Mulder, I. M. E., Shimizu, W., Nogami, A., Horigome, H., Roberts, J. D., Leenhardt, A., Crijns, H. J. G., Blank, A. C., Aiba, T., ... Wilde, A. A. M. (2019). Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm, 16(2), 220-228. https://doi.org/10.1016/j.hrthm.2018.08.025
    • Peeters, F. E. C. M., Kietselaer, B. L. J. H., Hilderink, J., van der Linden, N., Niens, M., Crijns, H. J. G. M., & Meex, S. J. R. (2019). Biological variation of cardiac markers in patients with aortic valve stenosis. Open Heart, 6(1), Article 001040. https://doi.org/10.1136/openhrt-2019-001040
    • Boriani, G., Fauchier, L., Aguinaga, L., Beattie, J. M., Lundqvist, C. B., Cohen, A., Dan, G.-A., Genovesi, S., Israel, C., Joung, B., Kalarus, Z., Lampert, R., Malavasi, V. L., Mansourati, J., Mont, L., Potpara, T., Thornton, A., Lip, G. Y. H., Gorenek, B., ... ESC Scientific Document Group (2019). European Heart Rhythm Association (EHRA) consensus document on management of arrhythmias and cardiac electronic devices in the critically ill and post-surgery patient, endorsed by Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin American Heart Rhythm Society (LAHRS). EP Europace, 21(1), 7-8. https://doi.org/10.1093/europace/euy110
    • Vroomen, M., Maesen, B., Luermans, J. G., Crijns, H. J., Maessen, J. G., Meir, M. L., & Pison, L. (2019). Left Atrial Appendage Management with the Watchman Device during Hybrid Ablation of Atrial Fibrillation. Journal of Interventional Cardiology, 2019, Article 4525084. https://doi.org/10.1155/2019/4525084
    • Hoorn, C. J. G. M., Crijns, H. J. G. M., Dierick-van Daele, A. T. M., & Dekker, L. R. C. (2019). Review on Factors Influencing Physician Guideline Adherence in Cardiology. Cardiology in Review, 27(2), 80-86. https://doi.org/10.1097/CRD.0000000000000207
    • Dudink, E., Florijn, B., Weijs, B., Duijs, J., Luermans, J., Peeters, F., Schurgers, L., Wildberger, J., Schotten, U., Bijkerk, R., Crijns, H. J., & van Zonneveld, A. J. (2019). Vascular Calcification and not Arrhythmia in Idiopathic Atrial Fibrillation Associates with Sex Differences in Diabetic Microvascular Injury miRNA Profiles. MicroRNA (Shāriqah, United Arab Emirates), 8(2), 127-134. https://doi.org/10.2174/2211536608666181122125208
  • 2018
    • Dudink, E. A. M. P., Weijs, B., Tull, S., Luermans, J. G. L. M., Fabritz, L., Chua, W., Rienstra, M., Van Gelder, I. C., Schotten, U., Kirchhof, P., & Crijns, H. J. G. M. (2018). The biomarkers NT-proBNP and CA-125 are elevated in patients with idiopathic atrial fibrillation. Journal of Atrial Fibrillation, 11(4). https://doi.org/10.4022/jafib.2058
    • van Stipdonk, A. M. W., ter Horst, I., Kloosterman, M., Engels, E. B., Rienstra, M., Crijns, H. J. G. M., Vos, M. A., van Gelder, I. C., Prinzen, F. W., Meine, M., Maass, A. H., & Vernooy, K. (2018). QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy. Circulation-Arrhythmia and Electrophysiology, 11(12), Article 006497. https://doi.org/10.1161/CIRCEP.118.006497
    • Strik, M., Ploux, S., Huntjens, P. R., Nguyen, U. C., Frontera, A., Eschalier, R., Dubois, R., Ritter, P., Klotz, N., Vernooy, K., Haissaguerre, M., Crijns, H. J. G. M., Prinzen, F. W., & Bordachar, P. (2018). Response to cardiac resynchronization therapy is determined by intrinsic electrical substrate rather than by its modification. International Journal of Cardiology, 270, 143-148. https://doi.org/10.1016/j.ijcard.2018.06.005