Prochaska, J. H., Frank, B., Nagler, M., Lamparter, H., Weisser, G., Schulz, A., Eggebrecht, L., Goebel, S., Arnold, N., Panova-Noeva, M., Hermanns, I., Pinto, A., Konstantinides, S., ten Cate, H., Lackner, K. J., Muenzel, T., Espinola-Klein, C., & Wild, P. S. (2017). Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis. Scientific Reports, 7(1), Article 4591. https://doi.org/10.1038/s41598-017-04843-x

Sabrkhany, S., Kuijpers, M. J. E., van Kuijk, S. M. J., Sanders, L., Pineda, S., Damink, S. W. M. O., Dingemans, A.-M. C., Griffioen, A. W., & Egbrink, M. G. A. O. (2017). A combination of platelet features allows detection of early-stage cancer. European Journal of Cancer, 80, 5-13. https://doi.org/10.1016/j.ejca.2017.04.010

Orsini, S., Noris, P., Bury, L., Heller, P. G., Santoro, C., Kadir, R. A., Butta, N. C., Falcinelli, E., Cid, A. R., Fabris, F., Fouassier, M., Miyazaki, K., Luisa Lozano, M., Zuniga, P., Flaujac, C., Podda, G. M., Bermejo, N., Favier, R., Henskens, Y., ... EHA-SWG Thrombocytopenias Platelet (2017). Bleeding risk of surgery and its prevention in patients with inherited platelet disorders. Haematologica-the Hematology Journal, 102(7), 1192-1203. https://doi.org/10.3324/haematol.2016.160754

ten Cate, H., Hackeng, T. M., & de Frutos, P. G. (2017). Coagulation factor and protease pathways in thrombosis and cardiovascular disease. Thrombosis and Haemostasis, 117(7), 1265-1271. https://doi.org/10.1160/TH17-02-0079

Honickel, M., Spronk, H. M., Rossaint, R., Stoppe, C., van Ryn, J., ten Cate, H., & Grottke, O. (2017). Dose requirements for idarucizumab reversal of dabigatran in a lethal porcine trauma model with continuous bleeding. Thrombosis and Haemostasis, 117(7), 1370-1378. https://doi.org/10.1160/TH16-11-0824

Prochaska, J. H., Goebel, S., Keller, K., Coldewey, M., Ullmann, A., Lamparter, H., Schulz, A., Schinzel, H., Bickel, C., Lauterbach, M., Michal, M., Hardt, R., Binder, H., Espinola-Klein, C., Lackner, K. J., Ten Cate, H., Muenzel, T., & Wild, P. S. (2017). e-Health-based management of patients receiving oral anticoagulation therapy: results from the observational thrombEVAL study. Journal of Thrombosis and Haemostasis, 15(7), 1375-1385. https://doi.org/10.1111/jth.13727

van der Linden, N., Streng, A. S., Bekers, O., Wodzig, W. K. W. H., Meex, S. J. R., & de Boer, D. (2017). Large Variation in Measured Cardiac Troponin T Concentrations after Standard Addition in Serum or Plasma of Different Individuals. Clinical Chemistry, 63(7), 1300-1302. https://doi.org/10.1373/clinchem.2017.272435

Ridger, V. C., Boulanger, C. M., Angelillo-Scherrer, A., Badimon, L., Blanc-Brude, O., Bochaton-Piallat, M.-L., Boilard, E., Buzas, E. I., Caporali, A., Dignat-George, F., Evans, P. C., Lacroix, R., Lutgens, E., Ketelhuth, D. F. J., Nieuwland, R., Toti, F., Tunon, J., Weber, C., Hoefer, I. E., ... Harrison, P. (2017). Microvesicles in vascular homeostasis and diseases Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology. Thrombosis and Haemostasis, 117(7), 1296-1316. https://doi.org/10.1160/TH16-12-0943

Hilderink, J. M., Klinkenberg, L. J. J., Aakre, K. M., de Wit, N. C. J., Henskens, Y. M. C., van der Linden, N., Bekers, O., Rennenberg, R. J. M. W., Koopmans, R. P., & Meex, S. J. R. (2017). Within-day biological variation and hour-to-hour reference change values for hematological parameters. Clinical Chemistry and Laboratory Medicine, 55(7), 1013-1024. https://doi.org/10.1515/cclm-2016-0716

Schmidt, M., Toplak, A., Quaedflieg, P. J. L. M., Ippel, H., Richelle, G. J. J., Hackeng, T. M., van Maarseveen, J. H., & Nuijens, T. (2017). Omniligase-1: A Powerful Tool for Peptide Head-to-Tail Cyclization. Advanced Synthesis & Catalysis, 359(12), 2050-2055. https://doi.org/10.1002/adsc.201700314

van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y.-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Mueller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., ... Munroe, P. B. (2017). Discovery of novel heart rate-associated loci using the Exome Chip. Human Molecular Genetics, 26(12), 2346-2363. https://doi.org/10.1093/hmg/ddx113

Arts, M., Soons, Z., Ellis, S. R., Pierzchalski, K. A., Balluff, B., Eijkel, G. B., Dubois, L. J., Lieuwes, N. G., Agten, S. M., Hackeng, T. M., van Loon, L. J. C., Heeren, R. M. A., & Damink, S. W. M. O. (2017). Detection of Localized Hepatocellular Amino Acid Kinetics by using Mass Spectrometry Imaging of Stable Isotopes. Angewandte Chemie-International Edition, 56(25), 7146-7150. https://doi.org/10.1002/anie.201702669

Putaala, J., Martinez-Majander, N., Saeed, S., Yesilot, N., Jakala, P., Nerg, O., Tsivgoulis, G., Numminen, H., Gordin, D., von Sarnowski, B., Waje-Andreassen, U., Ylikotila, P., Roine, R. O., Zedde, M., Huhtakangas, J., Fonseca, C., Redfors, P., de Leeuw, F. E., Pezzini, A., ... Tatlisumak, T. (2017). Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Triggers, Causes, and Outcome (SECRETO): Rationale and design. European Stroke Journal, 2(2), 116-125. https://doi.org/10.1177/2396987317703210

Vajen, T., Benedikter, B. J., Heinzmann, A. C. A., Vasina, E. M., Henskens, Y., Parsons, M., Maguire, P. B., Stassen, F. R., Heemskerk, J. W. M., Schurgers, L. J., & Koenen, R. R. (2017). Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype. Journal of Extracellular Vesicles, 6(1), Article 1322454. https://doi.org/10.1080/20013078.2017.1322454

Oshagbemi, O. A., Burden, A. M., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Driessen, J. H. M., Maitland-van der Zee, A. H., de Vries, F., & Franssen, F. M. E. (2017). Stability of Blood Eosinophils in Patients with Chronic Obstructive Pulmonary Disease and in Control Subjects, and the Impact of Sex, Age, Smoking, and Baseline Counts. American Journal of Respiratory and Critical Care Medicine, 195(10), 1402-1404. https://doi.org/10.1164/rccm.201701-0009LE

Aarts, S. A. B. M., Seijkens, T. T. P., Kusters, P. J. H., van der Pol, S. M. A., Zarzycka, B., Heijnen, P. D. A. M., Beckers, L., den Toom, M., Gijbels, M. J. J., Boon, L., Weber, C., de Vries, H. E., Nicolaes, G. A. F., Dijkstra, C. D., Kooij, G., & Lutgens, E. (2017). Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. Journal of Neuroinflammation, 14(1), Article 105. https://doi.org/10.1186/s12974-017-0875-9

Sohail, M., Vakhrusheva, O. A., Sul, J. H., Pulit, S. L., Francioli, L. C., van den Berg, L. H., Veldink, J. H., de Bakker, P. I. W., Bazykin, G. A., Kondrashov, A. S., Sunyaev, S. R., Genome of the Netherlands Consortium, & Isaacs, A. (2017). Negative selection in humans and fruit flies involves synergistic epistasis. Science, 356(6337), 539-542. https://doi.org/10.1126/science.aah5238

Van Der Linden, N., Streng, A. S., Wodzig, W. K. W. H., Bekers, O., & Meex, S. J. R. (2017). Better, higher, lower, faster: increasingly rapid clinical decision making using high-sensitivity cardiac troponin assays. Journal of Laboratory and Precision Medicine, 2, Article 14. https://doi.org/10.21037/jlpm.2017.04.03

Kremers, R. M. W., Kleinegris, M.-C., Ninivaggi, M., de Laat, B., ten Cate, H., Koek, G. H., Wagenvoord, R. J., & Hemker, H. C. (2017). Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis. PLOS ONE, 12(5), Article 0177020. https://doi.org/10.1371/journal.pone.0177020

Bloemen, S., Zwaveling, S., ten Cate, H., ten Cate-Hoek, A., & de Laat, B. (2017). Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing. PLOS ONE, 12(5), Article e0176967. https://doi.org/10.1371/journal.pone.0176967

Westhoff, C. L., Pike, M. C., Cremers, S., Eisenberger, A., Thomassen, S., & Rosing, J. (2017). Endogenous thrombin potential changes during the first cycle of oral contraceptive use. Contraception, 95(5), 456-463. https://doi.org/10.1016/j.contraception.2017.01.001

Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., Henry, R. M. A., Verhey, F. R. J., Kroon, A. A., Schaper, N. C., Dagnelie, P. C., Kallen, C. J. H. V. D., Stehouwer, C. D. A., & Biessels, G. J. (2017). Insulin resistance and cognitive performance in type 2 diabetes - The Maastricht study. Journal of Diabetes and Its Complications, 31(5), 824-830. https://doi.org/10.1016/j.jdiacomp.2017.01.020

Meani, P., Gelsomino, S., Natour, E., Johnson, D. M., Rocca, H.-P. B. L., Pappalardo, F., Bidar, E., Makhoul, M., Raffa, G., Heuts, S., Lozekoot, P., Kats, S., Sluijpers, N., Schreurs, R., Delnoij, T., Montalti, A., Sels, J. W., van de Poll, M., Roekaerts, P., ... Lorusso, R. (2017). Modalities and Effects of Left Ventricle Unloading on Extracorporeal Life support: a Review of the Current Literature. European journal of heart failure, 19 Suppl 2, 84-91. https://doi.org/10.1002/ejhf.850

Alshaikh, N. A., Rosing, J., Thomassen, M. C. L. G. D., Castoldi, E., Simioni, P., & Hackeng, T. M. (2017). New functional assays to selectively quantify the activated protein C- and tissue factor pathway inhibitor-cofactor activities of protein S in plasma. Journal of Thrombosis and Haemostasis, 15(5), 950-960. https://doi.org/10.1111/jth.13657

Veugen, M. G. J., Henry, R. M. A., van Sloten, T. T., Hermeling, E., Brunner-La Rocca, H.-P., Schram, M. T., Dagnelie, P. C., Schalkwijk, C. G., Kroon, A. A., Stehouwer, C. D. A., & Reesink, K. D. (2017). The systolic-diastolic difference in carotid stiffness is increased in type 2 diabetes: The Maastricht Study. Journal of Hypertension, 35(5), 1052-1060. https://doi.org/10.1097/HJH.0000000000001298

van der Velde, J. H. P. M., Savelberg, H. H. C. M., van der Berg, J. D., Sep, S. J. S., van der Kallen, C. J. H., Dagnelie, P. C., Schram, M. T., Henry, R. M. A., Reijven, P. L. M., van Geel, T. A. C. M., Stehouwer, C. D. A., Koster, A., & Schaper, N. C. (2017). Sedentary Behavior Is Only Marginally Associated with Physical Function in Adults Aged 40-75 Years - the Maastricht Study. Frontiers in physiology, 8(APR), Article 242. https://doi.org/10.3389/fphys.2017.00242

Kleinegris, M.-C. F., Konings, J., Daemen, J. W., Henskens, Y., de Laat, B., Spronk, H. M. H., ten Cate-Hoek, A. J., & ten Cate, H. (2017). Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case-Control Study. Frontiers in Cardiovascular Medicine, 4, Article 23. https://doi.org/10.3389/fcvm.2017.00023

Hobbelt, A. H., Spronk, H. M., Crijns, H. J. G. M., Ten Cate, H., Rienstra, M., & Van Gelder, I. C. (2017). Prethrombotic State in Young Very Low- Risk Patients With Atrial Fibrillation. Journal of the American College of Cardiology, 69(15), 1990-1992. https://doi.org/10.1016/j.jacc.2017.01.057

von Hundelshausen, P., Agten, S. M., Eckardt, V., Blanchet, X., Schmitt, M. M., Ippel, H., Neideck, C., Bidzhekov, K., Leberzammer, J., Wichapong, K., Faussner, A., Drechsler, M., Grommes, J., van Geffen, J. P., Li, H., Ortega-Gomez, A., Megens, R. T. A., Naumann, R., Dijkgraaf, I., ... Weber, C. (2017). Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation. Science Translational Medicine, 9(384), Article eaah6650. https://doi.org/10.1126/scitranslmed.aah6650

den Biggelaar, L. J. C. J., Eussen, S. J. P. M., Sep, S. J. S., Mari, A., Ferrannini, E., van Dongen, M. C. J. M., Denissen, K. F. M., Wijckmans, N. E. G., Schram, M. T., van der Kallen, C. J., Koster, A., Schaper, N., Henry, R. M. A., Stehouwer, C. D. A., & Dagnelie, P. C. (2017). Associations of Dietary Glucose, Fructose, and Sucrose with beta-Cell Function, Insulin Sensitivity, and Type 2 Diabetes in the Maastricht Study. Nutrients, 9(4), Article 380. https://doi.org/10.3390/nu9040380

Martens, R. J. H., Kimenai, D. M., Kooman, J. P., Stehouwer, C. D. A., Tan, F. E. S., Bekers, O., Dagnelie, P. C., van der Kallen, C. J. H., Kroon, A. A., Leunissen, K. M. L., van der Sande, F. M., Schaper, N. C., Sep, S. J. S., Schram, M. T., van Suijlen, J. D., van Dieijen-Visser, M. P., Meex, S. J. R., & Henry, R. M. A. (2017). Estimated Glomerular Filtration Rate and Albuminuria Are Associated with Biomarkers of Cardiac Injury in a Population-Based Cohort Study: The Maastricht Study. Clinical Chemistry, 63(4), 887-897. https://doi.org/10.1373/clinchem.2016.266031

van Smaalen, T. C., Beurskens, D. M. H., Hoogland, E. R. P., Winkens, B., Christiaans, M. H. L., Reutelingsperger, C. P., van Heurn, L. W. E., & Nicolaes, G. A. F. (2017). Presence of Cytotoxic Extracellular Histones in Machine Perfusate of Donation After Circulatory Death Kidneys. Transplantation, 101(4), e93-e101. https://doi.org/10.1097/TP.0000000000001590

Driessen, J. H. M., de Vries, F., van Onzenoort, H., Harvey, N. C., Neef, C., van den Bergh, J. P. W., Vestergaard, P., & Henry, R. M. A. (2017). The use of incretins and fractures - a meta-analysis on population-based real life data. British Journal of Clinical Pharmacology, 83(4), 923-926. https://doi.org/10.1111/bcp.13167

Ruhle, F., & Stoll, M. (2017). Genetic factors in pediatric venous thromboembolism. Thrombosis Research, 151, S97-S99. https://doi.org/10.1016/S0049-3848(17)30077-4

van Moorsel, D., Henry, R. M., Schaper, N. C., van Greevenbroek, M. M., van Rossum, E. F., 't Hart, L. M., Schalkwijk, C. G., van der Kallen, C. J., Dekker, J. M., Stehouwer, C. D., & Havekes, B. (2017). BclI Glucocorticoid Receptor Polymorphism in Relation to Arterial Stiffening and Cardiac Structure and Function: The Hoorn and CODAM Studies. American Journal of Hypertension, 30(3), 286-294. https://doi.org/10.1093/ajh/hpw196

Mingels, A. M. A., Cardinaels, E. P. M., Broers, N. J. H., van Sleeuwen, A., Streng, A. S., van Dieijen-Visser, M. P., Kooman, J. P., & Bekers, O. (2017). Cardiac Troponin T: Smaller Molecules in Patients with End-Stage Renal Disease than after Onset of Acute Myocardial Infarction. Clinical Chemistry, 63(3), 683-690. https://doi.org/10.1373/clinchem.2016.261644

Driessen, J. H. M., van den Bergh, J. P. W., van Onzenoort, H. A. W., Henry, R. M. A., Leufkens, H. G. M., & de Vries, F. (2017). Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture: A retrospective population-based cohort study. Diabetes Obesity & Metabolism, 19(3), 421-428. https://doi.org/10.1111/dom.12843

Simons, N., Isaacs, A., Koek, G. H., Kuc, S., Schaper, N. C., & Brouwers, M. C. G. J. (2017). PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease. Gastroenterology, 152(4), 912-913. https://doi.org/10.1053/j.gastro.2016.12.020

Kapustin, A. N., Schoppet, M., Schurgers, L. J., Reynolds, J. L., McNair, R., Heiss, A., Jahnen-Dechent, W., Hackeng, T. M., Schlieper, G., Harrison, P., & Shanahan, C. M. (2017). Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification. Arteriosclerosis Thrombosis and Vascular Biology, 37(3), E22-E32. https://doi.org/10.1161/ATVBAHA.116.308886

Kicken, C. H., Roest, M., Henskens, Y. M. C., de Laat, B., & Huskens, D. (2017). Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates. PLOS ONE, 12(2), Article e0172265. https://doi.org/10.1371/journal.pone.0172265

Ruehle, F., Witten, A., Barysenka, A., Huge, A., Arning, A., Heller, C., Kruempel, A., Mesters, R., Franke, A., Lieb, W., Riemenschneider, M., Hiersche, M., Limperger, V., Nowak-Goettl, U., & Stoll, M. (2017). Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism. Blood, 129(6), 783-790. https://doi.org/10.1182/blood-2016-07-728840

Winckers, K., Thomassen, S., ten Cate, H., & Hackeng, T. M. (2017). Platelet full length TFPI-alpha in healthy volunteers is not affected by sex or hormonal use. PLOS ONE, 12(2), Article 0168273. https://doi.org/10.1371/journal.pone.0168273

Arno, G., Carss, K. J., Hull, S., Zihni, C., Robson, A. G., Fiorentino, A., Hardcastle, A. J., Holder, G. E., Cheetham, M. E., Plagnol, V., Moore, A. T., Raymond, F. L., Matter, K., Balda, M. S., UK Inherited Retinal Dis, Henskens, Y., NIHR-BioResource Rare Dis, & Webster, A. R. (2017). Biallelic Mutation of ARHGEF18, Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration. American Journal of Human Genetics, 100(2), 334-342. https://doi.org/10.1016/j.ajhg.2016.12.014

Beer, A. J., & Dijkgraaf, I. (2017). Editorial European Journal of Nuclear Medicine and Molecular Imaging. European Journal of Nuclear Medicine and Molecular Imaging, 44(2), 284-285. https://doi.org/10.1007/s00259-016-3559-2

Martens, R. J. H., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Koster, A., Kroon, A. A., Leunissen, K. M. L., Nijpels, G., van der Sande, F. M., Schaper, N. C., Sep, S. J. S., van Boxtel, M. P. J., Schram, M. T., & Henry, R. M. A. (2017). Estimated GFR, Albuminuria, and Cognitive Performance: The Maastricht Study. American Journal of Kidney Diseases, 69(2), 179-191. https://doi.org/10.1053/j.ajkd.2016.04.017

Streng, A. S., de Boer, D., van Doom, W. P. T. M., Bouwman, F. G., Mariman, E. C. M., Bekers, O., van Dieijen-Visser, M. P., & Wodzig, W. K. W. H. (2017). Identification and and Characterization of Cardiac Troponin T Fragments in Serum of Patients Suffering from Acute Myocardial Infarction. Clinical Chemistry, 63(2), 563-572. https://doi.org/10.1373/clinchem.2016.261511

van Bussel, B. C. T., van de Poll, M. C. G., Schalkwijk, C. G., & Bergmans, D. C. J. J. (2017). Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness. International journal of molecular sciences, 18(2), Article 346. https://doi.org/10.3390/ijms18020346

Elands, R. J. J., Simons, C. C. J. M., Riemenschneider, M., Isaacs, A., Schouten, L. J., Verhage, B. A., Van Steen, K., Godschalk, R. W. L., van den Brandt, P. A., Stoll, M., & Weijenberg, M. P. (2017). A systematic SNP selection approach to identify mechanisms underlying disease aetiology: linking height to post-menopausal breast and colorectal cancer risk. Scientific Reports, 7, Article 41034. https://doi.org/10.1038/srep41034

van der Vorst, E. P. C., Theodorou, K., Wu, Y., Hoeksema, M. A., Goossens, P., Bursill, C. A., Aliyev, T., Huitema, L. F. A., Tas, S. W., Wolfs, I. M. J., Kuijpers, M. J. E., Gijbels, M. J., Schalkwijk, C. G., Koonen, D. P. Y., Abdollahi-Roodsaz, S., McDaniels, K., Wang, C.-C., Leitges, M., Lawrence, T., ... Donners, M. M. P. C. (2017). High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-kappa B/STAT1-IRF1 Signaling. Cell Metabolism, 25(1), 197-207. https://doi.org/10.1016/j.cmet.2016.10.013