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van der Velde, J. H. P. M., Schaper, N. C., Stehouwer, C. D. A., van der Kallen, C. J. H., Sep, S. J. S., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., Eussen, S. J. P. M., van Dongen, M. C. J. M., Savelberg, H. H. C. M., & Koster, A. (2018). Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study. Diabetologia, 61(12), 2561-2569. https://doi.org/10.1007/s00125-018-4719-7

Amin, E. E., Bistervels, I. M., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G., van de Poel, M., Serne, E. H., Otten, H. M., Klappe, E. M., Joore, M. A., ten Cate, H., ten Wolde, M., & ten Cate-Hoek, A. J. (2018). Reduced incidence of vein occlusion and postthrombotic syndrome after immediate compression for deep vein thrombosis. Blood, 132(21), 2298-2304. https://doi.org/10.1182/blood-2018-03-836783

Braza, M. S., van Leent, M. M. T., Lameijer, M., Sanchez-Gaytan, B. L., Arts, R. J. W., Perez-Medina, C., Conde, P., Garcia, M. R., Gonzalez-Perez, M., Brahmachary, M., Fay, F., Kluza, E., Kossatz, S., Dress, R. J., Salem, F., Rialdi, A., Reiner, T., Boros, P., Strijkers, G. J., ... Ochando, J. (2018). Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity, 49(5), 819-828.e6. https://doi.org/10.1016/j.immuni.2018.09.008

Favresse, J., Lippi, G., Roy, P.-M., Chatelain, B., Jacqmin, H., ten Cate, H., & Mullier, F. (2018). D-dimer: Preanalytical, analytical, postanalytical variables, and clinical applications . Critical Reviews in Clinical Laboratory Sciences, 55(8), 548-577. https://doi.org/10.1080/10408363.2018.1529734

Wildi, K., Singeisen, H., Twerenbold, R., Badertscher, P., Wussler, D., Klinkenberg, L. J. J., Meex, S. J. R., Nestelberger, T., Boeddinghaus, J., Miro, O., Martin-Sanchez, F. J., Morawiec, B., Muzyk, P., Parenica, J., Keller, D. I., Geigy, N., Potlukova, E., Sabti, Z., Kozhuharov, N., ... APACE Investigators (2018). Circadian rhythm of cardiac troponin I and its clinical impact on the diagnostic accuracy for acute myocardial infarction. International Journal of Cardiology, 270, 14-20. https://doi.org/10.1016/j.ijcard.2018.05.136

Balthasar, A. J. R., Bydlon, T. M., Ippel, H., van der Voort, M., Hendriks, B. H. W., Lucassen, G. W., van Geffen, G.-J., van Kleef, M., van Dijk, P., & Lataster, A. (2018). Optical signature of nerve tissue-Exploratory ex vivo study comparing optical, histological, and molecular characteristics of different adipose and nerve tissues. Lasers in Surgery and Medicine, 50(9), 948-960. https://doi.org/10.1002/lsm.22938

Oshagbemi, O. A., Franssen, F. M. E., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Maitland-van der Zee, A.-H., Burden, A. M., & de Vries, F. (2018). Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality. Pharmacoepidemiology and Drug Safety, 27(11), 1191-1199. https://doi.org/10.1002/pds.4655

Tilburg, J., Adili, R., Nair, T. S., Hawley, M. E., Tuk, D. C., Jackson, M., Spronk, H. M., Versteeg, H. H., Carey, T. E., van Vlijmen, B. J. M., Maracle, C. X., & Holinstat, M. (2018). Characterization of hemostasis in mice lacking the novel thrombosis susceptibility gene Slc44a2. Thrombosis Research, 171, 155-159. https://doi.org/10.1016/j.thromres.2018.09.057

Amin, E. E., ten Cate-Hoek, A. J., Bouman, A. C., Meijer, K., Tick, L., Middeldorp, S., Mostard, G., ten Wolde, M., van den Heiligenberg, S., van Wissen, S., van de Poet, M., Villalta, S., Serne, E., Otten, H. M., Klappe, E., Prandoni, P., Prins, M. H., ten Cate, H., & Joore, M. A. (2018). Individually shortened duration versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome: a cost-effectiveness analysis. The Lancet Haematology, 5(11), E512-E519. https://doi.org/10.1016/S2352-3026(18)30151-0

Goebel, S., Prochaska, J. H., Eggebrecht, L., Schmitz, R., Juenger, C., Lamparter, H., Nagler, M., Keller, K., Coldewey, M., Troebs, S.-O., Diestelmeier, S., Schwuchow-Thonke, S., Bickel, C., Lauterbach, M., Lackner, K. J., ten Cate, H., Muenzel, T., Hardt, R., & Wild, P. S. (2018). Management of Oral Anti-Coagulation in Patients with Heart Failure-Insights from the ThrombEVAL Study. Thrombosis and Haemostasis, 118(11), 1930-1939. https://doi.org/10.1055/s-0038-1673380

Liesenborghs, I., De Clerck, E. E. B., Berendschot, T. T. J. M., Goezinne, F., Schram, M. T., Henry, R. M. A., Stehouwer, C. D. A., Webers, C. A. B., & Schouten, J. S. A. G. (2018). Prevalence of optical coherence tomography detected vitreomacular interface disorders: The Maastricht Study. Acta Ophthalmologica, 96(7), 729-736. https://doi.org/10.1111/aos.13671

Pernot, C. C. E. G., Zwiers, I., ten Cate-Hoek, A. J., & Wittens, C. H. A. (2018). The need for a timely diagnostic workup for patients with venous leg ulcers. Journal of Wound Care, 27(11), 758-763. https://doi.org/10.12968/jowc.2018.27.11.758

Tullemans, B. M. E., Nagy, M., Sabrkhany, S., Griffioen, A. W., Egbrink, M. G. A. O., Aarts, M., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2018). Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients. Frontiers in Cardiovascular Medicine, 5, Article 142. https://doi.org/10.3389/fcvm.2018.00142

Gillissen, A., van den Akker, T., Caram-Deelder, C., Henriquez, D. D. C. A., Bloemenkamp, K. W. M., van Roosmalen, J. J. M., Eikenboom, J., van der Bom, J. G., Henskens, Y., Scheepers, L., & TeMpOH-1 study group (2018). Association between fluid management and dilutional coagulopathy in severe postpartum haemorrhage: a nationwide retrospective cohort study. BMC Pregnancy and Childbirth, 18(1), Article 398. https://doi.org/10.1186/s12884-018-2021-9

Zhou, T. L., Henry, R. M. A., Stehouwer, C. D. A., van Sloten, T. T., Reesink, K. D., & Kroon, A. A. (2018). Blood Pressure Variability, Arterial Stiffness, and Arterial Remodeling: The Maastricht Study. Hypertension, 72(4), 1002-1010. https://doi.org/10.1161/HYPERTENSIONAHA.118.11325

ten Cate, H., Lensing, A. W. A., Weitz, J. I., Middeldorp, S., Beyer-Westendorf, J., Kubitza, D., Brighton, T., Raskob, G. E., Mismetti, P., Prandoni, P., Gebel, M., & Prins, M. H. (2018). The prothrombin time does not predict the risk of recurrent venous thromboembolism or major bleeding in rivaroxaban-treated patients. Thrombosis Research, 170, 75-83. https://doi.org/10.1016/j.thromres.2018.08.008

Vries, M. J., van der Meijden, P. E., Kuiper, G. J., Nelemans, P. J., Wetzels, R. J., van Oerle, R. G., Lance, M. D., ten Cate, H., & Henskens, Y. M. (2018). Preoperative screening for bleeding disorders: A comprehensive laboratory assessment of clinical practice. Research and practice in thrombosis and haemostasis, 2(4), 767-777. https://doi.org/10.1002/rth2.12114

Peeters, F. E. C. M., Dudink, E. A. M. P., Kimenai, D. M., Weijs, B., Altintas, S., Heckman, L. I. B., Mihl, C., Schurgers, L. J., Wildberger, J. E., Meex, S. J. R., Kietselaer, B. L. J. H., & Crijns, H. J. G. M. (2018). Vitamin K Antagonists, Non-Vitamin K Antagonist Oral Anticoagulants, and Vascular Calcification in Patients with Atrial Fibrillation. TH open : companion journal to thrombosis and haemostasis, 2(4), e391-e398. https://doi.org/10.1055/s-0038-1675578

Hofmann, I., Geer, M. J., Vogtle, T., Crispin, A., Campagna, D. R., Barr, A., Calicchio, M. L., Heising, S., van Geffen, J. P., Kuijpers, M. J. E., Heemskerk, J. W. M., Eble, J. A., Schmitz-Abe, K., Obeng, E. A., Douglas, M., Freson, K., Pondarre, C., Favier, R., Jarvis, G. E., ... Senis, Y. A. (2018). Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice. Blood, 132(13), 1399-1412. https://doi.org/10.1182/blood-2017-08-802769

Geer, M. J., van Geffen, J. P., Gopalasingam, P., Vogtle, T., Smith, C. W., Heising, S., Kuijpers, M. J. E., Tullemans, B. M. E., Jarvis, G. E., Eble, J. A., Jeeves, M., Overduin, M., Heemskerk, J. W. M., Mazharian, A., & Senis, Y. A. (2018). Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis. Blood, 132(13), 1413-1425. https://doi.org/10.1182/blood-2017-10-802975

Zwaveling, S., Bloemen, S., de Laat, B., Ten Cate, H., & Ten Cate-Hoek, A. (2018). Calibrated Automated Thrombinography (CAT), a Tool to Identify Patients at Risk of Bleeding during Anticoagulant Therapy: A Systematic Review. TH open : companion journal to thrombosis and haemostasis, 2(3), 291-302. https://doi.org/10.1055/s-0038-1672183

Baaten, C. C. F. M. J., Swieringa, F., Misztal, T., Mastenbroek, T. G., Feijge, M. A. H., Bock, P. E., Donners, M. M. P. C., Collins, P. W., Li, R., van der Meijden, P. E. J., & Heemskerk, J. W. M. (2018). Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects. Blood advances, 2(18), 2320-2331. https://doi.org/10.1182/bloodadvances.2017011544

Koenen, R. R., & Aikawa, E. (2018). Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases. Frontiers in Cardiovascular Medicine, 5, Article 133. https://doi.org/10.3389/fcvm.2018.00133

Richelle, G. J. J., Schmidt, M., Ippel, H., Hackeng, T. M., van Maarseveen, J. H., Nuijens, T., & Timmerman, P. (2018). A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides. Chembiochem, 19(18), 1934-1938. https://doi.org/10.1002/cbic.201800346

Smulders, M. W., Bekkers, S. C. A. M., van Cauteren, Y. J. M., Liefhebber, A., Vermeer, J. R., Vervuurt, J., van Dieijen-Visser, M. P., Mingels, A. M. A., Rocca, H.-P. B.-L., Dagnelie, P. C., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Risk stratification and role for additional diagnostic testing in patients with acute chest pain and normal high-sensitivity cardiac troponin levels. PLOS ONE, 13(9), Article e0203506. https://doi.org/10.1371/journal.pone.0203506

van der Linden, N., Wildi, K., Twerenbold, R., Pickering, J. W., Than, M., Cullen, L., Greenslade, J., Parsonage, W., Nestelberger, T., Boeddinghaus, J., Badertscher, P., Gimenez, M., Klinkenberg, L. J. J., Bekers, O., Schoni, A., Keller, D. I., Sabti, Z., Puelacher, C., Cupa, J., ... Mueller, C. (2018). Combining High-Sensitivity Cardiac Troponin I and Cardiac Troponin T in the Early Diagnosis of Acute Myocardial Infarction. Circulation, 138(10), 989-999. https://doi.org/10.1161/CIRCULATIONAHA.117.032003

Eggebrecht, L., Prochaska, J. H., Schulz, A., Arnold, N., Juenger, C., Goebel, S., Laubert-Reh, D., Binder, H., Beutel, M. E., Pfeiffer, N., Blankenberg, S., Lackner, K. J., Spronk, H. M., ten Cate, H., Muenzel, T., & Wild, P. S. (2018). Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population-Based Gutenberg Health Study. Journal of the American Heart Association, 7(17), Article 008650. https://doi.org/10.1161/JAHA.118.008650

Henskens, Y., & NIHR BioResource - Rare Diseases (2018). Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Scientific Reports, 8(1), Article 13376. https://doi.org/10.1038/s41598-018-31524-0

Tullemans, B. M. E., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2018). Acquired platelet antagonism: off-target antiplatelet effects of malignancy treatment with tyrosine kinase inhibitors. Journal of Thrombosis and Haemostasis, 16(9), 1686-1699. https://doi.org/10.1111/jth.14225

Stifft, F., van Kuijk, S. M. J., Bekers, O., & Christiaans, M. H. L. (2018). Increase in tacrolimus exposure after steroid tapering is influenced by CYP3A5 and pregnane X receptor genetic polymorphisms in renal transplant recipients. Nephrology Dialysis Transplantation, 33(9), 1668-1675. https://doi.org/10.1093/ndt/gfy096

ten Cate, H. (2018). Testing direct oral anticoagulants: embedding in structured long-term care. Blood Transfusion, 16(5), 410-412. https://doi.org/10.2450/2017.0197-17

Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Roodt, J. O. H., Henry, R. M. A., Reesink, K. D., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2018). Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study. Atherosclerosis, 276, 15-22. https://doi.org/10.1016/j.atherosclerosis.2018.07.003

Baaten, C. C. F. M. J., Moenen, F. C. J. I., Henskens, Y. M. C., Swieringa, F., Wetzels, R. J. H., van Oerle, R., Heijnen, H. F. G., ten Cate, H., Holloway, G. P., Beckers, E. A. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2018). Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica-the Hematology Journal, 103(9), 1557-1567. https://doi.org/10.3324/haematol.2017.185165

Dickhout, A., & Koenen, R. R. (2018). Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks. Frontiers in Cardiovascular Medicine, 5, Article 113. https://doi.org/10.3389/fcvm.2018.00113

Schelpe, A.-S., Orlando, C., Ercig, B., Geeroms, C., Pareyn, I., Vandeputte, N., Pereira, L. C., Roose, E., Fostier, K., Nicolaes, G. A. F., Deckmyn, H., De Meyer, S. F., Vanhoorelbeke, K., & Jochmans, K. (2018). Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13. European Journal of Haematology, 101(2), 191-199. https://doi.org/10.1111/ejh.13094

Amin, E. E., Joore, M. A., ten Cate, H., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G. J. M., ten Wolde, M., Van den Heiligenberg, S. M., Van Wissen, S., Van de Poel, M. H. W., Villalta, S., Serne, E. H., Otten, H.-M., Klappe, E. H., Prandoni, P., & ten Cate-Hoek, A. J. (2018). Clinical and economic impact of compression in the acute phase of deep vein thrombosis. Journal of Thrombosis and Haemostasis, 16(8), 1555-1563. https://doi.org/10.1111/jth.14163

Crombag, G. A. J. C., Spronk, H. M., Nelemans, P., Schreuder, F. H. B. M., Truijman, M. T. B., van Dijk, A. C., de Rotte, A. A. J., Liem, M. I., Daemen, M. J. A. P., van der Steen, A. F. W., Mess, W. H., Nederkoorn, P. J., Hendrikse, J., van der Lugt, A., Wildberger, J. E., ten Cate, H., van Oostenbrugge, R. J., & Kooi, M. E. (2018). No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study. Thrombosis and Haemostasis, 118(8), 1461-1469. https://doi.org/10.1055/s-0038-1666858

Kremers, B. M. M., Ten Cate, H., & Spronk, H. M. H. (2018). Pleiotropic effects of the hemostatic system. Journal of Thrombosis and Haemostasis, 16(8), 1464-1473. https://doi.org/10.1111/jth.14161

Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., van der Kallen, C. J. H., Koster, A., Henry, R. M. A., Stehouwer, C. D. A., Savelkoul, P. H. M., Schaper, N. C., & Schram, M. T. (2018). Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study. Diabetes Care, 41(8), 1654-1662. https://doi.org/10.2337/dc17-2144

Witten, A., Bolbrinker, J., Barysenka, A., Huber, M., Ruhle, F., Nowak-Gottl, U., Garbe, E., Kreutz, R., & Stoll, M. (2018). Targeted resequencing of a locus for heparin-induced thrombocytopenia on chromosome 5 identified in a genome-wide association study. Journal of Molecular Medicine, 96(8), 765-775. https://doi.org/10.1007/s00109-018-1661-6

D'Alessandro, E., Posma, J. J. N., Spronk, H. M. H., & ten Cate, H. (2018). Tissue factor (:Factor VIIa) in the heart and vasculature: More than an envelope. Thrombosis Research, 168, 130-137. https://doi.org/10.1016/j.thromres.2018.06.020

Veugen, M. G. J., Henry, R. M. A., Brunner-La Rocca, H.-P., Dagnelie, P. C., Schram, M. T., van Agtmaal, M. J. M., van der Kallen, C. J. H., Sep, S. J. S., van Boxtel, M. P. J., Bekers, O., Meex, S. J. R., Jansen, J. F. A., Kroon, A. A., & Stehouwer, C. D. A. (2018). Cross-sectional associations between cardiac biomarkers, cognitive performance, and structural brain changes are modified by age: The Maastricht Study. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1948-1958. https://doi.org/10.1161/ATVBAHA.118.311082

van Setten, J., Brody, J. A., Jamshidi, Y., Swenson, B. R., Butler, A. M., Campbell, H., Del Greco, F. M., Evans, D. S., Gibson, Q., Gudbjartsson, D. F., Kerr, K. F., Krijthe, B. P., Lyytikainen, L.-P., Muller, C., Muller-Nurasyid, M., Nolte, I. M., Padmanabhan, S., Ritchie, M. D., Robino, A., ... Sotoodehnia, N. (2018). PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9(1), Article 2904. https://doi.org/10.1038/s41467-018-04766-9

Peeters, F. E. C. M., Meex, S. J. R., Dweck, M. R., Aikawa, E., Crijns, H. J. G. M., Schurgers, L. J., & Kietselaer, B. L. J. H. (2018). Calcific aortic valve stenosis: hard disease in the heart. European Heart Journal, 39(28), 2618–2624. https://doi.org/10.1093/eurheartj/ehx653

Vroemen, W. H. M., de Boer, D., Streng, A. S., Mingels, A. M. A., & Meex, S. J. R. (2018). Elevated Cardiac Troponin T in Skeletal Myopathies: Skeletal TnT Cross-Reactivity and/or Cardiac TnT Expression?Journal of the American College of Cardiology, 72(3), 347-349. https://doi.org/10.1016/j.jacc.2018.05.017

Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., ... Jamshidi, Y. (2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology, 19(1), Article 87. https://doi.org/10.1186/s13059-018-1457-6

Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8(1), Article 10647. https://doi.org/10.1038/s41598-018-29026-0

Whitworth, J., Smith, P. S., Martin, J.-E., West, H., Luchetti, A., Rodger, F., Clark, G., Carss, K., Stephens, J., Stirrups, K., Penkett, C., Mapeta, R., Ashford, S., Megy, K., Shakeel, H., Ahmed, M., Adlard, J., Barwell, J., Brewer, C., ... NIHR BioResource Rare Diseases Consortium (2018). Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. American Journal of Human Genetics, 103(1), 3-18. https://doi.org/10.1016/j.ajhg.2018.04.013

Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonca, C., Nava, C., Pfundt, R., Sanchis-Juan, A., van Bokhoven, H., van Essen, A., van Ravenswaaij-Arts, C., Boycott, K. M., Kernohan, K. D., Dyack, S., Raymond, F. L., ... Care4Rare Canada Consortium (2018). De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics, 103(1), 144-153. https://doi.org/10.1016/j.ajhg.2018.06.001