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Team Science grant Uyen Nguyen and Roel Meiburg

Team Science grant Uyen Nguyen and Roel Meiburg

18 December 2024

Dr Uyen Nguyen (Dept of Cardiology) and Dr Roel Meiburg (Biomedical Engineer, TU Eindhoven) have been awarded a Dekker Team Science grant by the Dutch Heart Foundation.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

10 December 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.
 

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Carim Maastricht
Carim Maastricht

Iwan van der Horst

Professor

 Prof. Iwan van der Horst was the principal investigator of the Simple Intensive Care Studies (SICS). In this ongoing registry, up to 2000 patients were included to unravel the diagnostic and prognostic value of physical and physiological examination. Based on the variables included, physicians make clinical decisions in the sickest patients every day. The design paper is published in the BMJ Open.

He was a leading investigator of clinical studies on critically ill patients focusing on hemodynamics, the heart in non-cardiac disease and acute kidney failure at the ICU. The team was involved in initiatives that combine the best of a prospective cohort study (like SICS-I, SOCCS and SICS-II) and randomised controlled trial design. The protocols were based upon results of systematic reviews (see Prospero).

He was also a co-primary investigator in clinical studies on myocardial infarction and heart failure, especially about (glucose) metabolism. Like the Metformin to Reduce Heart Failure After Myocardial Infarction (GIPS-III), NCT01217307. With this study, they obtained a grant of the Netherlands Organization for Health Research and Development (ZonMW; project no. 40-41200-98-9139). Over 20 publications out of this structured study have been published.

Therefore, he was an investigator in the Glucose Insulin Potassium Study (GIPS) I and II, both supported by the Netherlands Heart Foundation (99.028 and 2003B277). Studies on the diagnostic and prognostic value of routine laboratory measures in critically ill patients and implementation study on secondary prevention.

Currently, he is part of a team dedicated to monitoring and big data in critical care patients. A big database is created and cleaned for specific questions regarding mortality. The first projects focus on clustering and validation of prediction models. With the heart on team science, this research line is open to collaboration.

Iwanvdhorst1

Department of Intensive Care
P. Debyelaan 25
6229 HX, Maastricht
Room number: 3.C1.056  
T: +31(0)43 387 63 87 

  • 2021
    • van Gassel, R. J. J., Bels, J., Remij, L., van Bussel, B. C. T., Posthuma, R., Gietema, H. A., Verbunt, J., van der Horst, I. C. C., Damink, S. W. M. O., van Santen, S., & van de Poll, M. C. G. (2021). Functional Outcomes and Their Association With Physical Performance in Mechanically Ventilated Coronavirus Disease 2019 Survivors at 3 Months Following Hospital Discharge: A Cohort Study. Critical Care Medicine, 49(10), 1726-1738. https://doi.org/10.1097/CCM.0000000000005089
    • Boekel, M. F., Venema, C. S., Kaufmann, T., van der Horst, I. C. C., Vos, J. J., & Scheeren, T. W. L. (2021). The effect of compliance with a perioperative goal-directed therapy protocol on outcomes after high-risk surgery: a before-after study. Journal of Clinical Monitoring and Computing, 35(5), 1193-1202. https://doi.org/10.1007/s10877-020-00585-w
    • Hulshof, A. M., Braeken, D. C. W., Ghossein-Doha, C., van Santen, S., Sels, J. W. E. M., Kuiper, G. J. A. J. M., van der Horst, I. C. C., ten Cate, H., van Bussel, B. C. T., Olie, R. H., & Henskens, Y. M. C. (2021). Hemostasis and fibrinolysis in COVID-19 survivors 6 months after intensive care unit discharge. Research and practice in thrombosis and haemostasis, 5(6), Article e12579. https://doi.org/10.1002/rth2.12579
    • Beldhuis, I. E., Marapin, R. S., Jiang, Y. Y., de Souza, N. F. S., Georgiou, A., Kaufmann, T., Forte, J. C., & van der Horst, I. C. C. (2021). Cognitive biases, environmental, patient and personal factors associated with critical care decision making: A scoping review. Journal of Critical Care, 64, 144-153. https://doi.org/10.1016/j.jcrc.2021.04.012
    • Kurniawati, E. R., Rutjens, V. G. H., Vranken, N. P. A., Delnoij, T. S. R., Lorusso, R., van der Horst, I. C. C., Maessen, J. G., & Weerwind, P. W. (2021). Quality of life following adult veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review. Quality of Life Research, 30(8), 2123-2135. https://doi.org/10.1007/s11136-021-02834-0
    • Forte, C., Voinea, A., Chichirau, M., Yeshmagambetova, G., Albrecht, L. M., Erfurt, C., Freundt, L. A., Carmo, L. O. E., Henning, R. H., van der Horst, I. C. C., Sundelin, T., Wiering, M. A., Axelsson, J., & Epema, A. H. (2021). Deep Learning for Identification of Acute Illness and Facial Cues of Illness. Frontiers in medicine, 8, Article 661309. https://doi.org/10.3389/fmed.2021.661309
    • Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R. X., Imberger, G., Jensen, B. T., Jonsson, A. B., ... Wetterslev, J. (2021). A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions. Journal of Clinical Epidemiology, 135, 29-41. https://doi.org/10.1016/j.jclinepi.2021.01.023
    • Driessen, R. G. H., Kiers, D., Schalkwijk, C. G., Scheijen, J. L. J. M., Gerretsen, J., Pickkers, P., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., Kox, M., & van Bussel, B. C. T. (2021). Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males. Bioscience Reports, 41(7), Article BSR20210954. https://doi.org/10.1042/BSR20210954
    • Lemkes, J. S., Spoormans, E. M., Demirkiran, A., Leutscher, S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., ... van Royen, N. (2021). The effect of immediate coronary angiography after cardiac arrest without ST-segment elevation on left ventricular function. A sub-study of the COACT randomised trial. Resuscitation, 164, 93-100. https://doi.org/10.1016/j.resuscitation.2021.04.020
    • Donkers, M. A., Gilissen, V. J. H. S., Candel, M. J. J. M., van Dijk, N. M., Kling, H., Heijnen-Panis, R., Pragt, E., van der Horst, I., Pronk, S. A., & van Mook, W. N. K. A. (2021). Moral distress and ethical climate in intensive care medicine during COVID-19: a nationwide study. BMC Medical Ethics, 22(1), Article 73. https://doi.org/10.1186/s12910-021-00641-3
    • Heijnen, N. F. L., Hagens, L. A., Smit, M. R., Cremer, O. L., Ong, D. S. Y., van der Poll, T., van Vught, L. A., Scicluna, B. P., Schnabel, R. M., van der Horst, I. C. C., Schultz, M. J., Bergmans, D. C. J. J., Bos, L. D. J., & MARD Consortium (2021). Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine, 203(12), 1503-1511. https://doi.org/10.1164/rccm.202006-2522OC
    • Forte, J. C., Yeshmagambetova, G., van der Grinten, M. L., Hiemstra, B., Kaufmann, T., Eck, R. J., Keus, F., Epema, A. H., Wiering, M. A., & van der Horst, I. C. C. (2021). Identifying and characterizing high-risk clusters in a heterogeneous ICU population with deep embedded clustering. Scientific Reports, 11(1), Article 12109. https://doi.org/10.1038/s41598-021-91297-x
    • Blokzijl, F., Onrust, M., Dieperink, W., Keus, F., van der Horst, I. C. C., Paans, W., Mariani, M. A., & Reneman, M. F. (2021). Barriers That Obstruct Return to Work After Coronary Bypass Surgery: A Qualitative Study. Journal of Occupational Rehabilitation, 31(2), 316-322. https://doi.org/10.1007/s10926-020-09919-6
    • Driessen, R. G. H., Latten, B. G. H., Bergmans, D. C. J. J., Hulsewe, R. P. M. G., Holtkamp, J. W. M., van der Horst, I. C. C., Kubat, B., & Schnabel, R. M. (2021). Clinical diagnoses vs. autopsy findings in early deceased septic patients in the intensive care: a retrospective cohort study. Virchows Archiv, 478(6), 1173-1178. https://doi.org/10.1007/s00428-020-02984-5
    • Bosveld, M. H., van Doorn, D. P. C., Stassen, P. M., Westerman, D., Bergmans, D. C. J. J., van der Horst, I. C. C., & van Mook, W. N. K. A. (2021). Lessons learned: Contribution to healthcare by medical students during COVID-19. Journal of Critical Care, 63, 113-116. https://doi.org/10.1016/j.jcrc.2020.09.015
    • Mulder, M. M. G., Brandts, LI., Brüggemann, R. A. G., Koelmann, M., Streng, A. S., Olie, R. H., Gietema, H. A., Spronk, H. M. H., van der Horst, I. C. C., Sels, J.-W. E. M., Wildberger, J. E., van Kuijk, S. M. J., Schnabel, R. M., Ten Cate, H., Henskens, Y. M. C., & van Bussel, B. C. T. (2021). Serial markers of coagulation and inflammation and the occurrence of clinical pulmonary thromboembolism in mechanically ventilated patients with SARS-CoV-2 infection; the prospective Maastricht intensive care COVID cohort. Thrombosis Journal, 19(1), Article 35. https://doi.org/10.1186/s12959-021-00286-7
    • Hulshof, A.-M., Brüggemann, R. A. G., Mulder, M. M. G., van de Berg, T. W., Sels, J.-W. E. M., Olie, R. H., Spaetgens, B., Streng, A. S., Verhezen, P., van der Horst, I. C. C., Ten Cate, H., Spronk, H. M. H., van Bussel, B. C. T., & Henskens, Y. M. C. (2021). Serial EXTEM, FIBTEM, and tPA Rotational Thromboelastometry Observations in the Maastricht Intensive Care COVID Cohort-Persistence of Hypercoagulability and Hypofibrinolysis Despite Anticoagulation. Frontiers in Cardiovascular Medicine, 8, Article 654174. https://doi.org/10.3389/fcvm.2021.654174
    • Meynaar, I. A., Ottens, T., Zegers, M., van Mol, M. M. C., & van der Horst, I. C. C. (2021). Burnout, resilience and work engagement among Dutch intensivists in the aftermath of the COVID-19 crisis: A nationwide survey. Journal of Critical Care, 62, 1-5. https://doi.org/10.1016/j.jcrc.2020.11.010
    • Bels, J. L. M., van Kuijk, S. M. J., Ghossein-Doha, C., Tijssen, F. H., van Gassel, R. J. J., Tas, J., Schnabel, R. M., Aries, M. J. H., van de Poll, M. M. G., Bergmans, D. C. J. J., Meex, S. J. R., van Mook, W. N. K. A., van der Horst, I. C. C., van Bussel, B. C. T., & MaastrICCht Collaborators (2021). Decreased serial scores of severe organ failure assessments are associated with survival in mechanically ventilated patients; the prospective Maastricht Intensive Care COVID cohort. Journal of Critical Care, 62, 38-45. https://doi.org/10.1016/j.jcrc.2020.11.006
    • Blokzijl, F., Houterman, S., van Straten, B. H. M., Daeter, E., Brandon Bravo Bruinsma, G. J., Dieperink, W., Reneman, M. F., Keus, F., van der Horst, I. C. C., & Mariani, M. A. (2021). The impact of surgical aortic valve replacement on quality of life-a multicenter study. Journal of Thoracic and Cardiovascular Surgery, 161(4), 1204-1210.e7. https://doi.org/10.1016/j.jtcvs.2019.09.184
    • Forte, J. C., Mungroop, H. E., de Geus, F., van der Grinten, M. L., Bouma, H. R., Pettila, V., Scheeren, T. W. L., Nijsten, M. W. N., Mariani, M. A., van der Horst, I. C. C., Henning, R. H., Wiering, M. A., & Epema, A. H. (2021). Ensemble machine learning prediction and variable importance analysis of 5-year mortality after cardiac valve and CABG operations. Scientific Reports, 11(1), Article 3467. https://doi.org/10.1038/s41598-021-82403-0
    • Heijnen, N. F. L., Hagens, L. A., Smit, M. R., Schultz, M. J., van der Poll, T., Schnabel, R. M., van der Horst, I. C. C., Dickson, R. P., Bergmans, D. C. J. J., Bos, L. D. J., & BASIC Consortium (2021). Biological subphenotypes of acute respiratory distress syndrome may not reflect differences in alveolar inflammation. Physiological Reports, 9(3), Article e14693. https://doi.org/10.14814/phy2.14693
    • Squara, P., Scheeren, T. W. L., Aya, H. D., Bakker, J., Cecconi, M., Einav, S., Malbrain, M. L. N. G., Monnet, X., Reuter, D. A., van der Horst, I. C. C., & Saugel, B. (2021). Metrology part 1: definition of quality criteria. Journal of Clinical Monitoring and Computing, 35(1), 17-25. https://doi.org/10.1007/s10877-020-00494-y
    • Squara, P., Scheeren, T. W. L., Aya, H. D., Bakker, J., Cecconi, M., Einav, S., Malbrain, M. L. N. G., Monnet, X., Reuter, D. A., van der Horst, I. C. C., & Saugel, B. (2021). Metrology part 2: Procedures for the validation of major measurement quality criteria and measuring instrument properties. Journal of Clinical Monitoring and Computing, 35(1), 27-37. https://doi.org/10.1007/s10877-020-00495-x
    • Linschoten, M., Nab, L., van der Horst, I. C. C., Tieleman, R., & Asselbergs, F. W. (2021). Response to "Early hydroxychloroquine but not chloroquine use reduces ICU admission in COVID-19 patients". International Journal of Infectious Diseases, 103, 560-561. https://doi.org/10.1016/j.ijid.2020.12.006
    • Scheeren, T. W. L., Bakker, J., Kaufmann, T., Annane, D., Asfar, P., Boerma, E. C., Cecconi, M., Chew, M. S., Cholley, B., Cronhjort, M., De Backer, D., Dubin, A., Dunser, M. W., Duranteau, J., Gordon, A. C., Hajjar, L. A., Hamzaoui, O., Hernandez, G., Edul, V. K., ... Teboul, J. L. (2021). Current use of inotropes in circulatory shock. Annals of Intensive Care, 11(1), Article 21. https://doi.org/10.1186/s13613-021-00806-8
    • Eck, R. J., Hulshof, L., Wiersema, R., Thio, C. H. L., Hiemstra, B., van den Oever, N. C. G., Gans, R. O. B., van der Horst, I. C. C., Meijer, K., & Keus, F. (2021). Incidence, prognostic factors, and outcomes of venous thromboembolism in critically ill patients: data from two prospective cohort studies. Critical Care, 25(1), Article 27. https://doi.org/10.1186/s13054-021-03457-0
    • Ariës, M. J. H., van den Bergh, J. P., Beudel, M., Boersma, W., Dormans, T., Douma, R. A., Eerens, A., Elbers, P. W. G., Fleuren, L. M., Gritters van den Oever, N. C., de Haan, L., van der Horst, I. J. C. C., Hu, S., Hubers, D., Janssen, M. L. F., de Kruif, M., Kubben, P. L., van Kuijk, S. M. J., Noordzij, P. G., ... Wyers, C. E. (2021). Klinisch beloop van covid-19 in Nederland: Een overzicht van 2607 ziekenhuispatiënten uit de eerste golf. Nederlands Tijdschrift voor Geneeskunde, 165(3), Article D5085. https://www.ntvg.nl/artikelen/klinisch-beloop-van-covid-19-nederland
    • Driessen, R. G. H., Heijnen, N. F. L., Hulsewe, R. P. M. G., Holtkamp, J. W. M., Winkens, B., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., & Schnabel, R. M. (2021). Early ICU-mortality in sepsis - causes, influencing factors and variability in clinical judgement: a retrospective cohort study. Infectious Diseases, 53(1), 61-68. https://doi.org/10.1080/23744235.2020.1821912
    • van Dam, P. M. E. L., Zelis, N., van Kuijk, S. M. J., Linkens, A. E. M. J. H., Bruggemann, R. A. G., Spaetgens, B., van der Horst, I. C. C., & Stassen, P. M. (2021). Performance of prediction models for short-term outcome in COVID-19 patients in the emergency department: a retrospective study. Annals of Medicine, 53(1), 402-409. https://doi.org/10.1080/07853890.2021.1891453
    • Spoormans, E. M., Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., van de Ven, P. M., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., ... van Royen, N. (2021). Sex differences in patients with out-of-hospital cardiac arrest without ST-segment elevation: A COACT trial substudy. Resuscitation, 158, 14-22. https://doi.org/10.1016/j.resuscitation.2020.10.026
    • Sanfilippo, F., Huang, S., Herpain, A., Balik, M., Chew, M. S., Clau-Terre, F., Corredor, C., De Backer, D., Fletcher, N., Geri, G., Mekontso-Dessap, A., McLean, A., Morelli, A., Orde, S., Petrinic, T., Slama, M., van der Horst, I. C. C., Vignon, P., Mayo, P., & Vieillard-Baron, A. (2021). The PRICES statement: an ESICM expert consensus on methodology for conducting and reporting critical care echocardiography research studies. Intensive Care Medicine, 47(1), 1-13. https://doi.org/10.1007/s00134-020-06262-5
    • Blokzijl, F., Keus, F., Houterman, S., Dieperink, W., Van Der Horst, I. C. C., Reneman, M. F., Absalom, A. R., & Mariani, M. A. (2021). Does postoperative cognitive decline after coronary bypass affect quality of life?Open Heart, 8(1), Article e001569. https://doi.org/10.1136/openhrt-2020-001569
    • Ottenhoff, M. C., Ramos, L. A., Potters, W., Janssen, M. L. F., Hubers, D., Hu, S., Fridgeirsson, E. A., Pina-Fuentes, D., Thomas, R., van der Horst, I. C. C., Herff, C., Kubben, P., Elbers, P. W. G., Marquering, H. A., Welling, M., Simsek, S., de Kruif, M. D., Dormans, T., Fleuren, L. M., ... Dutch COVID-PREDICT research group (2021). Predicting mortality of individual patients with COVID-19: a multicentre Dutch cohort. BMJ Open, 11(7), Article e047347. https://doi.org/10.1136/bmjopen-2020-047347
  • 2020
    • Smit, M. R., de Vos, J., Pisani, L., Hagens, L. A., Almondo, C., Heijnen, N. F. L., Schnabel, R. M., van der Horst, I. C., Bergmans, D. C. J. J., Schultz, M. J., Bos, L. D. J., & DARTS Consortium (2020). Comparison Of Linear And Sector Array Probe For Handheld Lung Ultrasound In Invasively Ventilated Icu Patients. Ultrasound in Medicine and Biology, 46(12), 3249-3256. https://doi.org/10.1016/j.ultrasmedbio.2020.08.016
    • Vlaar, A. P. J., de Bruin, S., Busch, M., Timmermans, S. A. M. E. G., van Zeggeren, I. E., Koning, R., ter Horst, L., Bulle, E. B., van Baarle, F. E. H. P., van de Poll, M. C. G., Kemper, E. M., van der Horst, I. C. C., Schultz, M. J., Horn, J., Paulus, F., Bos, L. D., Wiersinga, W. J., Witzenrath, M., Rueckinger, S., ... van de Beek, D. (2020). Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial. The Lancet Rheumatology, 2(12), E764-E773. https://doi.org/10.1016/s2665-9913(20)30341-6
    • Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M. M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R. R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., Beishuizen, A., Stoel, M., ... van Royen, N. (2020). Coronary Angiography After Cardiac Arrest Without ST Segment Elevation: One-Year Outcomes of the COACT Randomized Clinical Trial. JAMA Cardiology, 5(12), 1358-1365. https://doi.org/10.1001/jamacardio.2020.3670
    • Bruggemann, R. A. G., Spaetgens, B., Gietema, H. A., Brouns, S. H. A., Stassen, P. M., Magdelijns, F. J., Rennenberg, R. J., Henry, R. M. A., Mulder, M. M. G., van Bussel, B. C. T., Schnabel, R. M., van der Horst, I. C. C., Wildberger, J. E., Stehouwer, C. D. A., & ten Cate, H. (2020). The prevalence of pulmonary embolism in patients with COVID-19 and respiratory decline: A three-setting comparison. Thrombosis Research, 196, 486-490. https://doi.org/10.1016/j.thromres.2020.10.012
    • Schiffer, V. M. M. M., Janssen, E. B. N. J., van Bussel, B. C. T., Jorissen, L. L. M., Tas, J., Sels, J.-W. E. M., Bergmans, D. C. J. J., Dinh, T. H. T., van Kuijk, S. M. J., Hana, A., Mehagnoul-Schipper, J., Scheeren, C. I. E., Mesotten, D., Stessel, B., Marx, G., Hof, A. W. J. V. T., Spaanderman, M. E. A., van Mook, W. N. K. A., van der Horst, I. C. C., & Ghossein-Doha, C. (2020). The "sex gap" in COVID-19 trials: a scoping review. EClinicalMedicine, 29-30, Article 100652. https://doi.org/10.1016/j.eclinm.2020.100652
    • Busch, M. H., Timmermans, S. A. M. E. G., Nagy, M., Visser, M., Huckriede, J., Aendekerk, J. P., de Vries, F., Potjewijd, J., Jallah, B., Ysermans, R., Oude Lashof, A. M. L., Breedveld, P. H., van de Poll, M. C. G., van de Horst, I. C. C., van Bussel, B. C. T., Theunissen, R. O. M. F. I. H., Spronk, H. M. H., Damoiseaux, J. G. M. C., ten Cate, H., ... van Paassen, P. (2020). Neutrophils and Contact Activation of Coagulation as Potential Drivers of COVID-19. Circulation, 142(18), 1787-1790. https://doi.org/10.1161/CIRCULATIONAHA.120.050656
    • Wiersema, R., Kaufmann, T., van der Veen, H. N., de Haas, R. J., Franssen, C. F. M., Koeze, J., van der Horst, I. C. C., Keus, F., & SICS Study Group (2020). Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients: A prospective study. Journal of Critical Care, 59, 57-62. https://doi.org/10.1016/j.jcrc.2020.05.012
    • van den Akker, E. B., Trompet, S., Barkey Wolf, J. J. H., Beekman, M., Suchiman, H. E. D., Deelen, J., Asselbergs, F. W., Boersma, E., Cats, D., Elders, P. M., Geleijnse, J. M., Ikram, M. A., Kloppenburg, M., Mei, H., Meulenbelt, I., Mooijaart, S. P., Nelissen, R. G. H. H., Netea, M. G., Penninx, B. W. J. H., ... Slagboom, P. E. (2020). Metabolic Age Based on the BBMRI-NL 1 H-NMR Metabolomics Repository as Biomarker of Age-related Disease. Circulation: Genomic and Precision Medicine, 13(5), 541-547. Article 002610. https://doi.org/10.1161/CIRCGEN.119.002610
    • Streng, A. S., Delnoij, T. S. R., Mulder, M. M. G., Sels, J. W. E. M., Wetzels, R. J. H., Verhezen, P. W. M., Olie, R. H., Kooman, J. P., van Kuijk, S. M. J., Brandts, L., Ten Cate, H., Lorusso, R., van der Horst, I. C. C., van Bussel, B. C. T., & Henskens, Y. M. C. (2020). Monitoring of Unfractionated Heparin in Severe COVID-19: An Observational Study of Patients on CRRT and ECMO. TH open : companion journal to thrombosis and haemostasis, 4(4), e365-e375. https://doi.org/10.1055/s-0040-1719083
    • Posma, R. A., Wessels, A. M. A., Dieperink, W., Roggeveld, J., Leuvenink, H. G. D., van der Horst, I. C. C., den Dunnen, W. F. A., Nijsten, M. W., & Touw, D. J. (2020). Renal Trapping in Accidental Metformin Intoxication. Kidney International Reports, 5(9), 1525-1528. https://doi.org/10.1016/j.ekir.2020.06.009
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