• 2014
    • Elliott, P. M., Anastasakis, A., Borger, M. A., Borggrefe, M., Cecchi, F., Charron, P., Hagege, A. A., Lafont, A., Limongelli, G., Mahrholdt, H., McKenna, W. J., Mogensen, J., Nihoyannopoulos, P., Nistri, S., Pieper, P. G., Pieske, B., Rapezzi, C., Rutten, F. H., Tillmanns, C., ... Watkins, H. (2014). 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). European Heart Journal, 35(39), 2733-2779. https://doi.org/10.1093/eurheartj/ehu284
    • Abdurrachim, D., Ciapaite, J., Wessels, B., Nabben, M., Luiken, J. J. F. P., Nicolay, K., & Prompers, J. J. (2014). Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1841(10), 1525-1537. https://doi.org/10.1016/j.bbalip.2014.07.016
    • Jacobs, L., Thijs, L., Jin, Y., Zannad, F., Mebazaa, A., Rouet, P., Pinet, F., Bauters, C., Pieske, B., Tomaschitz, A., Mamas, M., Diez, J., McDonald, K., Cleland, J. G. F., Brunner-La Rocca, H.-P., Heymans, S., Latini, R., Masson, S., Sever, P., ... Staessen, J. A. (2014). Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database. Journal of Biomedical Research, 28(5), 349-59. https://doi.org/10.7555/JBR.28.20140045
    • Kapsokalyvas, D., Schiffers, P. M. H., Maij, N., Suylen, D. P., Hackeng, T. M., van Zandvoort, M. A. M. J., & De Mey, J. G. R. (2014). Imaging evidence for endothelin ETA/ETB receptor heterodimers in isolated rat mesenteric resistance arteries. Life Sciences, 111(1-2), 36-41. https://doi.org/10.1016/j.lfs.2014.07.007
    • van der Linden, N., Klinkenberg, L. J. J., Meex, S. J. R., Beckers, E. A. M., de Wit, N. C. J., & Prinzen, L. (2014). Immature platelet fraction measured on the Sysmex XN hemocytometer predicts thrombopoietic recovery after autologous stem cell transplantation. European Journal of Haematology, 93(2), 150-156. https://doi.org/10.1111/ejh.12319
    • Chennupati, R., Meens, M. J., Marion, V., Janssen, B. J., Lamers, W. H., de Mey, J. G., & Kohler, S. E. (2014). Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice. PLOS ONE, 9(7), Article e102264. https://doi.org/10.1371/journal.pone.0102264
    • Westermann, D., & Heymans, S. (2014). Fibrosis or hypertrophy: let TIMPs decide. Cardiovascular Research, 103(2), 196-197. https://doi.org/10.1093/cvr/cvu160
    • Altara, R., Manca, M., Hessel, M. H. M., Janssen, B. J., Struijker-Boudier, H. H. A., Hermans, R. J. J., & Blankesteijn, M. (2014). Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample. BMC Biotechnology, 14, Article 63. https://doi.org/10.1186/1472-6750-14-63
    • Martins, P. A. D. C., Leptidis, S., & De Windt, L. J. (2014). Nuclear Calcium Transients Hermes Propylaios in the Heart. Circulation, 130(3), 221-223. https://doi.org/10.1161/CIRCULATIONAHA.114.010675
    • Murdoch, C. E., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer, A. C., Zhang, M., & Shah, A. M. (2014). Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition. Journal of the American College of Cardiology, 63(24), 2734-2741. https://doi.org/10.1016/j.jacc.2014.02.572
    • Troughton, R. W., Frampton, C. M., Brunner-La Rocca, H.-P., Pfisterer, M., Eurlings, L. W. M., Erntell, H., Persson, H., O'Connor, C. M., Moertl, D., Karlstrom, P., Dahlstrom, U., Gaggin, H. K., Januzzi, J. L., Berger, R., Richards, A. M., Pinto, Y. M., & Nicholls, M. G. (2014). Effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization: an individual patient meta-analysis. European Heart Journal, 35(23), 1559-1567. https://doi.org/10.1093/eurheartj/ehu090
    • Lemmens, K. J., van de Wier, B., Vaes, N., Ghosh, M., van Zandvoort, M. A., van der Vijgh, W., Bast, A., & Haenen, G. R. (2014). The flavonoid 7-mono-O-(beta-hydroxyethyl)-rutoside is able to protect endothelial cells by a direct antioxidant effect. Toxicology in Vitro, 28(4), 538-543. https://doi.org/10.1016/j.tiv.2013.12.019
    • Bekkers, S. C. A. M., & Brunner-La Rocca, H. P. (2014). Elderly primary care hypertension patients-who to refer for echocardiography?Netherlands Heart Journal, 22(5), 231-233. https://doi.org/10.1007/s12471-014-0550-z
    • Leite-Moreira, A. F., Lourenco, A. P., Balligand, J.-L., Bauersachs, J., Clerk, A., De Windt, L. J., Heymans, S., Hilfiker-Kleiner, D., Hirsch, E., Iaccarino, G., Kaminski, K. A., Knoell, R., Mayr, M., Tarone, G., Thum, T., & Tocchetti, C. G. (2014). ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models. European journal of heart failure, 16(5), 509-518. https://doi.org/10.1002/ejhf.66
    • Tarone, G., Balligand, J.-L., Bauersachs, J., Clerk, A., De Windt, L., Heymans, S., Hilfiker-Kleiner, D., Hirsch, E., Iaccarino, G., Knoell, R., Leite-Moreira, A. F., Lourenco, A. P., Mayr, M., Thum, T., & Tocchetti, C. G. (2014). Targeting myocardial remodelling to develop novel therapies for heart failure A position paper from the Working Group on Myocardial Function of the European Society of Cardiology. European journal of heart failure, 16(5), 494-508. https://doi.org/10.1002/ejhf.62
    • Milenkovic, D., Vanden Berghe, W., Boby, C., Leroux, C., Declerck, K., Szarc Vel Szic, K., Heyninck, K., Laukens, K., Bizet, M., Defrance, M., Dedeurwaerder, S., Calonne, E., Fuks, F., Haegeman, G., Haenen, G. R., Bast, A., & Weseler, A. R. (2014). Dietary Flavanols Modulate the Transcription of Genes Associated with Cardiovascular Pathology without Changes in Their DNA Methylation State. PLOS ONE, 9(4), Article e95527. https://doi.org/10.1371/journal.pone.0095527
    • Poels, E. M., Bitsch, N., Slenter, J. M., Kooi, M. E., de Theije, C. C., De Windt, L. J., van Empel, V. P., & da Costa Martins, P. A. (2014). Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice. PLOS ONE, 9(4), Article 92983. https://doi.org/10.1371/journal.pone.0092983
    • Kriemler, S., Buergi, F., Wick, C., Wick, B., Keller, M., Wiget, U., Schindler, C., Kaufmann, B. A., Kohler, M., Bloch, K., & Brunner-La Rocca, H.-P. (2014). Prevalence of Acute Mountain Sickness at 3500 m Within and Between Families: A Prospective Cohort Study. High Altitude Medicine & Biology, 15(1), 28-38. https://doi.org/10.1089/ham.2013.1073
    • Daskalopoulos, E. P., Hermans, K. C. M., & Blankesteijn, M. (2014). Cardiac (myo)fibroblast: Novel Strategies for its Targeting Following Myocardial Infarction. Current Pharmaceutical Design, 20(12), 1987-2002. https://doi.org/10.2174/13816128113199990452
    • Beaumont, J., Lopez, B., Hermida, N., Schroen, B., Jose, G. S., Heymans, S., Valencia, F., Jose Gomez-Doblas, J., De Teresa, E., Diez, J., & Gonzalez, A. (2014). microRNA-122 down-regulation may play a role in severe myocardial fibrosis in human aortic stenosis through TGF-beta(1) up-regulation. Clinical Science, 126(7-8), 497-506. https://doi.org/10.1042/CS20130538
    • Hendriks, J. M. L., Vrijhoef, H. J. M., Crijns, H. J. G. M., & Brunner-La Rocca, H. P. (2014). The effect of a nurse-led integrated chronic care approach on quality of life in patients with atrial fibrillation. EP Europace, 16(4), 491-499. https://doi.org/10.1093/europace/eut286
    • Kelly, E. R., Plat, J., Haenen, G. R., Kijlstra, A., & Berendschot, T. T. (2014). The effect of modified eggs and an egg-yolk based beverage on serum lutein and zeaxanthin concentrations and macular pigment optical density: results from a randomized trial. PLOS ONE, 9(3), Article 92659. https://doi.org/10.1371/journal.pone.0092659
    • Sanders-van Wijk, S., van Empel, V., Knackstedt, C., & Brunner-La Rocca, H.-P. (2014). Heart failure and COPD: Time to SHIFT?International Journal of Cardiology, 172(2), 293-294. https://doi.org/10.1016/j.ijcard.2013.12.285
    • Roncarati, R., Anselmi, C. V., Losi, M. A., Papa, L., Cavarretta, E., Martins, P. D. C., Contaldi, C., Jotti, G. S., Franzone, A., Galastri, L., Latronico, M. V. G., Imbriaco, M., Esposito, G., De Windt, L., Betocchi, S., & Condorelli, G. (2014). Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 63(9), 920-927. https://doi.org/10.1016/j.jacc.2013.09.041
    • Papageorgiou, A.-P., & Heymans, S. (2014). Peroxidasin-like protein: expanding the horizons of matrix biology. Cardiovascular Research, 101(3), 342-343. https://doi.org/10.1093/cvr/cvu017
    • Peeters, J. M. P. W. U., Sanders-van Wijk, S., Bektas, S., Knackstedt, C., Rickenbacher, P., Nietlispach, F., Handschin, R., Maeder, M. T., Muzzarelli, S. F., Pfisterer, M. E., & Brunner-La Rocca, H. P. (2014). Biomarkers in outpatient heart failure management; Are they correlated to and do they influence clinical judgment?Netherlands Heart Journal, 22(3), 115-121. https://doi.org/10.1007/s12471-013-0503-y
    • Heijnen, B. F. J., Pelkmans, L. P. J., Danser, A. H. J., Garrelds, I. M., Mullins, J. J., De Mey, J. G. R., Struijker-Boudier, H. A. J., & Janssen, B. J. A. (2014). Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats. Journal of the Renin-angiotensin-aldosterone System, 15(1), 69-81. https://doi.org/10.1177/1470320313480537
    • Rienks, M., Papageorgiou, A.-P., Frangogiannis, N. G., & Heymans, S. (2014). Myocardial Extracellular Matrix An Ever-Changing and Diverse Entity. Circulation Research, 114(5), 872-888. https://doi.org/10.1161/CIRCRESAHA.114.302533
    • Meyer, U., Schindler, C., Zahner, L., Ernst, D., Hebestreit, H., van Mechelen, W., Rocca, H.-P. B.-L., Probst-Hensch, N., Puder, J. J., & Kriemler, S. (2014). Long-Term Effect of a School-Based Physical Activity Program (KISS) on Fitness and Adiposity in Children: A Cluster-Randomized Controlled Trial. PLOS ONE, 9(2), Article e87929. https://doi.org/10.1371/journal.pone.0087929
    • Hazebroek, M. R., Everaerts, K., & Heymans, S. (2014). Diagnostic approach of myocarditis: strike the golden mean. Netherlands Heart Journal, 22(2), 80-84. https://doi.org/10.1007/s12471-013-0499-3
    • Van Empel, V. P. M., Kaufmann, B. A., Bernheim, A. M., Goetschalckx, K., Min, S. Y., Muzzarelli, S., Pfisterer, M. E., Kiencke, S., Maeder, M. T., & Brunner-La Rocca, H.-P. (2014). Interaction Between Pulmonary Hypertension and Diastolic Dysfunction in an Elderly Heart Failure Population. Journal of Cardiac Failure, 20(2), 98-104. https://doi.org/10.1016/j.cardfail.2013.12.010
    • Burkard, T., Pfister, O., Rickli, H., Follath, F., Hack, D., Zaker, R., Pittl, U., Handschin, R., Pfisterer, M., & Brunner-La Rocca, H. .-P. (2014). Prognostic impact of systemic inflammatory diseases in elderly patients with congestive heart failure. QJM: An International Journal of Medicine, 107(2), 131-138. https://doi.org/10.1093/qjmed/hct205
    • Heijnen, B. F. J., Van Essen, H., Schalkwijk, C. G., Janssen, B. J. A., & Struijker-Boudier, H. A. J. (2014). Renal inflammatory markers during the onset of hypertension in spontaneously hypertensive rats. Hypertension Research, 37(2), 100-109. https://doi.org/10.1038/hr.2013.99
    • Napp, A., Joosten, S., Stunder, D., Knackstedt, C., Zink, M., Bellmann, B., Marx, N., Schauerte, P., & Silny, J. (2014). Electromagnetic Interference With Implantable Cardioverter-Defibrillators at Power Frequency An In Vivo Study. Circulation, 129(4), 441-450. https://doi.org/10.1161/CIRCULATIONAHA.113.003081
    • van Bilsen, M., Daniels, A., Brouwers, O., Janssen, B. J. A., Derks, W. J. A., Brouns, A. E., Munts, C., Schalkwijk, C. G., van der Vusse, G. J., & van Nieuwenhoven, F. A. (2014). Hypertension Is a Conditional Factor for the Development of Cardiac Hypertrophy in Type 2 Diabetic Mice. PLOS ONE, 9(1), Article e85078. https://doi.org/10.1371/journal.pone.0085078
    • Sthijns, M. M., Randall, M. J., Bast, A., & Haenen, G. R. (2014). Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: The materialization of the hormesis concept.Biochemical and Biophysical Research Communications, 446(4), 1029-1034. https://doi.org/10.1016/j.bbrc.2014.03.081
    • Hazebroek, M. R., van Paassen, P., Weerwind, P. W., Cooper, L. T. . J., Uriel, N., Caliskan, K., de Vries, B., Maessen, J. G., Autschbach, R., Heymans, S., & Donker, D. W. (2014). A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. International Journal of Cardiology, 170(3), E74-E75. https://doi.org/10.1016/j.ijcard.2013.11.028
    • Hazewindus, M., Haenen, G. R., Weseler, A. R., & Bast, A. (2014). Protection against Chemotaxis in the Anti-Inflammatory Effect of Bioactives from Tomato Ketchup. PLOS ONE, 9(12), Article e114387. https://doi.org/10.1371/journal.pone.0114387
    • Marsch, E., Theelen, T. L., Demandt, J. A., Jeurissen, M., van Gink, M., Verjans, R., Janssen, A., Cleutjens, J. P., Meex, S. J., Donners, M. M., Haenen, G., Schalkwijk, C. G., Dubois, L. J., Lambin, P., Mallat, Z., Gijbels, M. J., Heemskerk, J. W., Fisher, E. A., Biessen, E. A., ... Sluimer, J. C. (2014). Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis. Arteriosclerosis Thrombosis and Vascular Biology, 34(12), 2545-2553. https://doi.org/10.1161/ATVBAHA.114.304023
    • Ruijters, E. J., Haenen, G. R., Weseler, A. R., & Bast, A. (2014). The cocoa flavanol (-)-epicatechin protects the cortisol response.Pharmacological Research, 79, 28-33. https://doi.org/10.1016/j.phrs.2013.11.004
    • Lemmens, K. J., Vrolijk, M. F., Bouwman, F. G., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2014). The Minor Structural Difference between the Antioxidants Quercetin and 4'O-Methylquercetin Has a Major Impact on Their Selective Thiol. International journal of molecular sciences, 15(5), 7475-7484. https://doi.org/10.3390/ijms15057475
    • Brouwers, O., Niessen, P. M. G., Miyata, T., Ostergaard, J. A., Flyvbjerg, A., Peutz-Kootstra, C. J., Sieber, J., Mundel, P. H., Brownlee, M., Janssen, B. J. A., De Mey, J. G. R., Stehouwer, C. D. A., & Schalkwijk, C. G. (2014). Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes. Diabetologia, 57(1), 224-235. https://doi.org/10.1007/s00125-013-3088-5
    • Sanders-van Wijk, S., Maeder, M. T., Nietlispach, F., Rickli, H., Estlinbaum, W., Erne, P., Rickenbacher, P., Peter, M., Pfisterer, M. P., & Brunner-La Rocca, H.-P. (2014). Long-Term Results of Intensified, N-Terminal-Pro-B-Type Natriuretic Peptide-Guided Versus Symptom-Guided Treatment in Elderly Patients With Heart Failure Five-Year Follow-Up From TIME-CHF. Circulation-Heart Failure, 7(1), 131-139. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000527
    • Hohl, M., Ardehali, H., Azuaje, F. J., Breckenridge, R. A., Doehner, W., Eaton, P., Ehret, G. B., Fujita, T., Gaetani, R., Giacca, M., Hasenfuss, G., Heymans, S., Leite-Moreira, A. F., Linke, W. A., Linz, D., Lyon, A., Mamas, M. A., Oresic, M., Papp, Z., ... Maack, C. (2014). Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research. European journal of heart failure, 16(1), 6-14. https://doi.org/10.1002/ejhf.10
    • Mafi Rad, M., Blaauw, Y., Debie, L., Brunner-La Rocca, H., & Vernooy, K. (2014). Evaluation of Left Ventricular Endocardial Cardiac Resynchronization Therapy in a Non-responder with Ventricular Arrhythmias. Indian pacing and electrophysiology journal, 14(1), 32-6. https://doi.org/10.1016/S0972-6292(16)30713-6
    • van Dongen, M., van Kraaij, D., Schalla, S., Brunner-La Rocca, H., & Driessen, R. (2014). Severe mitral regurgitation caused by eosinophilic endocarditis. Journal of Cardiology Cases, 10(3). https://doi.org/10.1016/j.jccase.2014.05.012
    • van Buchem, M. A., Biessels, G. J., la Rocca, H. P. B., de Craen, A. J. M., van der Flier, W. M., Ikram, M. A., Kappelle, L. J., Koudstaal, P. J., Mooijaart, S. P., Niessen, W., van Oostenbrugge, R., de Roos, A., van Rossum, A. C., & Daemen, M. J. A. P. (2014). The Heart-Brain Connection: A Multidisciplinary Approach Targeting a Missing Link in the Pathophysiology of Vascular Cognitive Impairment. Journal of Alzheimer's Disease, 42, S443-S451. https://doi.org/10.3233/JAD-141542