Publications
- 2015
- Benedikter, B. J., Volgers, C., Haenen, G. R. M. M., Savelkoul, P. H. M., Wouters, E. F. M., Rohde, G. G. U., Weseler, A. R., & Stassen, F. R. M. (2015). Cigarette smoke extract induces the release of extracellular vesicles by airway epithelial cells via cellular carbonyl stress. European Respiratory Journal, 46(suppl 59). https://doi.org/10.1183/13993003.congress-2015.PA5113
- Knackstedt, C., Hildebrandt, U., Schmidt, K., Syrocki, L., Lang, A., Bjarnason-Wehrens, B., Schummers, G., Stapf, D., Becker, M., & Predel, H. G. (2015). Analysis of right and left ventricular deformation in former world class swimmers: evaluation using speckle tracking. Journal of Sports Medicine and Physical Fitness, 55(9), 978-987. https://www.scopus.com/record/display.uri?eid=2-s2.0-84962505145&origin=inward
- Cannon, M. V., Sillje, H. H. W., Sijbesma, J. W. A., Vreeswijk-Baudoin, I., Ciapaite, J., van der Sluis, B., van Deursen, J., Silva, G. J. J., de Windt, L. J., Gustafsson, J.-A., van der Harst, P., van Gilst, W. H., & de Boer, R. A. (2015). Cardiac LXR protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization. EMBO Molecular Medicine, 7(9), 1229-1243. https://doi.org/10.15252/emmm.201404669
- el Azzouzi, H., Leptidis, S., Doevendans, P. A., & De Windt, L. J. (2015). HypoxamiRs: regulators of cardiac hypoxia and energy metabolism. Trends in Endocrinology and Metabolism, 26(9), 502-508. https://doi.org/10.1016/j.tem.2015.06.008
- Salden, B. N., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Editorial: enhancing gluten digestion in the stomach- a further help to minimise unintentional ingestion? Authors' reply. Alimentary Pharmacology & Therapeutics, 42(4), 485. https://doi.org/10.1111/apt.13296
- Heymans, S., Gonzalez, A., Pizard, A., Papageorgiou, A. P., Lopez-Andres, N., Jaisser, F., Thum, T., Zannad, F., & Diez, J. (2015). Searching for new mechanisms of myocardial fibrosis with diagnostic and/or therapeutic potential. European journal of heart failure, 17(8), 764-771. https://doi.org/10.1002/ejhf.312
- Kaufmann, B. A., Goetschalckx, K., Min, S. Y., Maeder, M. T., Bucher, U., Nietlispach, F., Bernheim, A. M., Pfisterer, M. E., Brunner-La Rocca, H. P., & TIME-CHF Investigators, T. (2015). Improvement in left ventricular ejection fraction and reverse remodeling in elderly heart failure patients on intense NT-proBNP-guided therapy. International Journal of Cardiology, 191, 286-293. https://doi.org/10.1016/j.ijcard.2015.04.282
- Papageorgiou, A.-P., Heggermont, W., Rienks, M., Carai, P., Langouche, L., Verhesen, W., De Boer, R. A., & Heymans, S. (2015). Liver X receptor activation enhances CVB3 viral replication during myocarditis by stimulating lipogenesis. Cardiovascular Research, 107(1), 78-88. https://doi.org/10.1093/cvr/cvv157
- Tchaikovski, V., Tchaikovski, S., Olieslagers, S., & Waltenberger, J. (2015). Monocyte dysfunction as a previously unrecognized pathophysiological mechanism in ApoE-/- mice contributing to impaired arteriogenesis. International Journal of Cardiology, 190(1), 214-216. https://doi.org/10.1016/j.ijcard.2015.04.188
- Devaux, Y., Zangrando, J., Schroen, B., Creemers, E. E., Pedrazzini, T., Chang, C.-P., Dorn, G. W. . II., Thum, T., & Heymans, S. (2015). Long noncoding RNAs in cardiac development and ageing. Nature Reviews Cardiology, 12(7), 415-425. https://doi.org/10.1038/nrcardio.2015.55
- Hermansand, K. C. M., & Blankesteijn, W. M. (2015). Wnt Signaling in Cardiac Disease. Comprehensive Physiology, 5(3), 1183-1209. https://doi.org/10.1002/cphy.c140060
- van Empel, V., & Brunner-La Rocca, H. P. (2015). Inflammation in HFpEF: Key or circumstantial?International Journal of Cardiology, 189(1), 259-263. https://doi.org/10.1016/j.ijcard.2015.04.110
- Daeichin, V., Akkus, Z., Skachkov, I., Kooiman, K., Needles, A., Sluimer, J., Janssen, B., Daemen, M. J. A. P., van der Steen, A. F. W., de Jong, N., & Bosch, J. G. (2015). Quantification of Bound Microbubbles in Ultrasound Molecular Imaging. Ieee Transactions on Ultrasonics Ferroelectrics and Frequency Control, 62(6), 1190-1200. https://doi.org/10.1109/TUFFC.2015.006264
- Neumann, D., Luiken, J. J. F. P., Nabben, M., & Glatz, J. F. C. (2015). Letter by Neumann et al Regarding Article, "Myostatin Regulates Energy Homeostasis in the Heart and Prevents Heart Failure". Circulation Research, 116(10), E95-E96. https://doi.org/10.1161/CIRCRESAHA.115.306463
- Abdurrachim, D., Luiken, J. J. F. P., Nicolay, K., Glatz, J. F. C., Prompers, J. J., & Nabben, M. (2015). Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models. Cardiovascular Research, 106(2), 194-205. https://doi.org/10.1093/cvr/cvv105
- Knackstedt, C., Schmidt, K., Syrocki, L., Lang, A., Bjarnason-Wehrens, B., Hildebrandt, U., & Predel, H.-G. (2015). Long-term follow-up of former world-class swimmers: evaluation of cardiovascular function. Heart and Vessels, 30(3), 369-378. https://doi.org/10.1007/s00380-014-0481-z
- Altara, R., Manca, M., Hermans, K. C., Daskalopoulos, E. P., Brunner-La Rocca, H. P., Hermans, R. J., Struijker-Boudier, H. A. J., & Blankesteijn, M. W. (2015). Diurnal rhythms of serum and plasma cytokine profiles in healthy elderly individuals assessed using membrane based multiplexed immunoassay. Journal of Translational Medicine, 13(1), Article 129. https://doi.org/10.1186/s12967-015-0477-1
- Poels, E. M., Martins, P. A. D. C., & van Empel, V. P. M. (2015). Adaptive capacity of the right ventricle: why does it fail?American Journal of Physiology-heart and Circulatory Physiology, 308(8), H803-H813. https://doi.org/10.1152/ajpheart.00573.2014
- Zurek, M., Maeder, M. T., Rickli, H., Muzzarelli, S., Sanders-van Wijk, S., Abbühl, H., Handschin, R., Jeker, U., Pfisterer, M. E., Brunner-La Rocca, H. P., & TIME-CHF Investigators, T. (2015). Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF. Journal of Cardiac Failure, 21(4), 347-354. https://doi.org/10.1016/j.cardfail.2014.12.014
- Schalla, S., Jaarsma, C., Bekkers, S. C., Waltenberger, J., Dennert, R., Crijns, H. J., Wildberger, J., Heymans, S., & Brunner-La Rocca, H. P. (2015). Right ventricular function in dilated cardiomyopathy and ischemic heart disease: assessment with non-invasive imaging. Netherlands Heart Journal, 23(4), 232-240. https://doi.org/10.1007/s12471-015-0673-x
- Diaz-Munoz, M. D., Bell, S. E., Fairfax, K., Monzon-Casanova, E., Cunningham, A. F., Gonzalez-Porta, M., Andrews, S. R., Bunik, V. I., Zarnack, K., Curk, T., Heggermont, W. A., Heymans, S., Gibson, G. E., Kontoyiannis, D. L., Ule, J., & Turner, M. (2015). The RNA-binding protein HuR is essential for the B cell antibody response. Nature Immunology, 16(4), 415-425. https://doi.org/10.1038/ni.3115
- Brunner-La Rocca, H. P., & Crijns, H. J. (2015). Iron i.v. in heart failure: ready for implementation?European Heart Journal, 36(11), 645-647. https://doi.org/10.1093/eurheartj/ehu392
- Duygu, B., & Martins, P. A. D. C. (2015). miR-21: a star player in cardiac hypertrophy. Cardiovascular Research, 105(3), 235-237. https://doi.org/10.1093/cvr/cvv026
- Gandhi, P. U., Motiwala, S. R., Belcher, A. M., Gaggin, H. K., Weiner, R. B., Baggish, A. L., Fiuzat, M., Rocca, H.-P. B.-L., & Januzzi, J. L. . J. (2015). Galectin-3 and mineralocorticoid receptor antagonist use in patients with chronic heart failure due to left ventricular systolic dysfunction. American Heart Journal, 169(3), 404-411. https://doi.org/10.1016/j.ahj.2014.12.012
- Berry, M., Galinier, M., Delmas, C., Fournier, P., Desmoulin, F., Turkieh, A., Mischak, H., Mullen, W., Barutaut, M., Eurlings, L. W., Van Wijk, S., Rocca, H.-P. B.-L., Caubere, C., Butler, J., Roncalli, J., Evaristi, M. F., Cohen-Solal, A., Seronde, M.-F., Escamilla, R., ... Rouet, P. (2015). Proteomics analysis reveals IGFBP2 as a candidate diagnostic biomarker for heart failure. International Journal of Cardiology - Metabolic & Endocrine, 6, 5-12. https://doi.org/10.1016/j.ijcme.2014.11.003
- Ounzain, S., Micheletti, R., Beckmann, T., Schroen, B., Alexanian, M., Pezzuto, I., Crippa, S., Nemir, M., Sarre, A., Johnson, R., Dauvillier, J., Burdet, F., Ibberson, M., Guigo, R., Xenarios, I., Heymans, S., & Pedrazzini, T. (2015). Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs. European Heart Journal, 36(6), 353–368. https://doi.org/10.1093/eurheartj/ehu180
- Kornmann, L. M., Zernecke, A., Curfs, D. M. J., Janssen, B. J. A., Weber, C., de Winther, M. P. J., Reneman, R. S., Hoeks, A. P. G., & Reesink, K. D. (2015). Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study. Cardiovascular Ultrasound, 13(1), Article 1. https://doi.org/10.1186/1476-7120-13-1
- Vrolijk, M. F., Haenen, G. R., Opperhuizen, A., Jansen, E. H., Schiffers, P. M., & Bast, A. (2015). The supplement-drug interaction of quercetin with tamsulosin on vasorelaxation. European Journal of Pharmacology, 746, 132-137. https://doi.org/10.1016/j.ejphar.2014.11.006
- Van Wijk, S., Van Empel, V., Davarzani, N., Maeder, M. T., Muzzarelli, S., Jeker, U., Dieterle, T., Handschin, R., Kiencke, S., Pfisterer, M. E., Brunner-La Rocca, H. P., & investigators, F. T. TIME.-CHF. (2015). Circulating biomarkers of distinct pathophysiological pathways in heart failure with preserved vs. reduced left ventricular ejection fraction. European journal of heart failure, 17(10), 1006-1014. https://doi.org/10.1002/ejhf.414
- Cardinaels, E. P. M., Daamen, M. A. M. J., Bekers, O., ten Kate, J., Niens, M., van Suijlen, J. D. E., van Dieijen-Visser, M. P., Brunner-La Rocca, H. P., Schols, J. M. G. A., & Mingels, A. M. A. (2015). Clinical Interpretation of Elevated Concentrations of Cardiac Troponin T, but Not Troponin I, in Nursing Home Residents. Journal of the American Medical Directors Association, 16(10), 884-891. https://doi.org/10.1016/j.jamda.2015.06.026
- Vrolijk, M. F., Haenen, G., Bast, A., Opperhuizen, A., & Jansen, E. (2015). Een voorbeeld van onderbelichte geneesmiddel-voedingssupplement interactie. Orthostatische hypotensie door tamsulosine en quercetine. PiL, 2015(3), 20-23. https://www.pil-nascholing.nl/tijdschrift/editie/artikel/t/een-voorbeeld-van-onderbelichte-geneesmiddel-voedingssupplement-interactie
- Brunner-La Rocca, H. P., Knackstedt, C., Eurlings, L., Rolny, V., Krause, F., Pfisterer, M. E., Tobler, D., Rickenbacher, P., Maeder, M. T., & TIME-CHF Investigators, T. (2015). Impact of worsening renal function related to medication in heart failure. European journal of heart failure, 17(2), 159-168. https://doi.org/10.1002/ejhf.210
- Balk, J. M., Haenen, G. R. M., Koc, O. M., Peters, R., Bast, A., van der Vijgh, W. J. F., & Koek, G. H. (2015). Once-daily dose regimen of ribavirin is interchangeable with a twice-daily dose regimen: randomized open clinical trial. Pharmacogenomics and personalized medicine, 8, 137-144. https://doi.org/10.2147/pgpm.s82782
- van Aelst, L. N., Voss, S., Carai, P., van Leeuwen, R., Vanhoutte, D., Sanders-van Wijk, S., Eurlings, L., Swinnen, M., Verheyen, F. K., Verbeken, E., Nef, H., Troidl, C., Cook, S. A., Brunner-La Rocca, H. P., Möllmann, H., Papageorgiou, A. P., & Heymans, S. (2015). Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening. Circulation Research, 116(3), 425-436. https://doi.org/10.1161/CIRCRESAHA.116.304599
- Salden, B., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Alimentary Pharmacology & Therapeutics, 42(3), 273-285. https://doi.org/10.1111/apt.13266
- Varon, C., Alao, M., Mintert, J., Stapleton, M., Thomson, S., Jaecques, S., Brunner-La Rocca, H. P., & Huffel, S. V. (2015). Telehealth on heart failure: results of the Recap project. Journal of Telemedicine and Telecare, 21(6), 340-347. https://doi.org/10.1177/1357633X15577310
- Lemmens, K., van de Wier, B., Koek, G. H., Köhler, E. S., Drittij, M. J., van der Vijgh, W., Bast, A., & Haenen, G. R. (2015). The flavonoid monoHER promotes the adaption to oxidative stress during the onset of NAFLD. Biochemical and Biophysical Research Communications, 456(1), 179-182. https://doi.org/10.1016/j.bbrc.2014.11.055
- Vrolijk, M. F., Opperhuizen, A., Jansen, E. H., Godschalk, R. W., van Schooten, F. J., Bast, A., & Haenen, G. R. (2015). The shifting perception on antioxidants: The case of vitamin E and beta-carotene. Redox Biology, 4C, 272-278. https://doi.org/10.1016/j.redox.2014.12.017
- Bryant, C. E., Gay, N. J., Heymans, S., Sacre, S., Schaefer, L., & Midwood, K. S. (2015). Advances in Toll-like receptor biology: Modes of activation by diverse stimuli. Critical Reviews in Biochemistry and Molecular Biology, 50(5), 359-379. https://doi.org/10.3109/10409238.2015.1033511
- Daskalopoulos, E. P., Vilaeti, A. D., Barka, E., Mantzouratou, P., Kouroupis, D., Kontonika, M., Tourmousoglou, C., Papalois, A., Pantos, C., Blankesteijn, W. M., Agathopoulos, S., & Kolettis, T. M. (2015). Attenuation of post-infarction remodeling in rats by sustained myocardial growth hormone administration. Growth Factors, 33(4), 250-258. https://doi.org/10.3109/08977194.2015.1072527
- Brunner-La Rocca, H., & Bektas, S. (2015). Biomarker guided therapy in chronic heart failure. Cardiac Failure Review, 1(2), 96-101. https://doi.org/10.15420/cfr.2015.1.2.96
- 2014
- Emmens, R. W., Woudstra, L., Papageorgiou, A., Carai, P., Smit, S., Seven-Deniz, S., Rozendaal, L., Paulus, W. J., Wouters, D., Zeerleder, S., Murk, J.-L., van Ham, M. S., Heymans, S., van Rossum, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2014). Lymphocytes Infiltrate the Quadriceps Muscle in Lymphocytic Myocarditis Patients: A Potential New Diagnostic Tool. Canadian Journal of Cardiology, 30(12), 1547-1554. https://doi.org/10.1016/j.cjca.2014.07.018
- Eurlings, L. W., Sanders-van Wijk, S., van Kraaij, D. J. W., van Kimmenade, R., Meeder, J. G., Kamp, O., van Dieijen-Visser, M. P., Tijssen, J. G. P., Brunner-La Rocca, H.-P., & Pinto, Y. M. (2014). Risk stratification with the use of serial N-terminal pro-B-type natriuretic peptide measurements during admission and early after discharge in heart failure patients: post hoc analysis of the PRIMA study. Journal of Cardiac Failure, 20(12), 881-90. https://doi.org/10.1016/j.cardfail.2014.08.014
- Haenen, G. R. M., & Bast, A. (2014). Glutathione revisited: a better scavenger than previously thought. Frontiers in Pharmacology, 5(NOV), Article 260. https://doi.org/10.3389/fphar.2014.00260
- Reinhardt, B., Godfrey, R., Fellbrich, G., Frank, H., Lueske, A., Olieslagers, S., Mertens, T., & Waltenberger, J. (2014). Human cytomegalovirus infection impairs endothelial cell chemotaxis by disturbing VEGF signalling and actin polymerization. Cardiovascular Research, 104(2), 315-325. https://doi.org/10.1093/cvr/cvu204
- Skobel, E., Martinez-Romero, A., Scheibe, B., Schauerte, P., Marx, N., Luprano, J., & Knackstedt, C. (2014). Evaluation of a newly designed shirt-based ECG and breathing sensor for home-based training as part of cardiac rehabilitation for coronary artery disease. European Journal of Preventive Cardiology, 21(11), 1332-1340. https://doi.org/10.1177/2047487313493227
- Nabben, M., van Bree, B. W., Lenaers, E., Hoeks, J., Hesselink, M. K., Schaart, G., Gijbels, M. J., Glatz, J. F., da Silva, G. J., De Windt, L. J., Tian, R., Mike, E., Skapura, D. G., Wehrens, X. H., & Schrauwen, P. (2014). Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death.Basic Research in Cardiology, 109(6), Article 447. https://doi.org/10.1007/s00395-014-0447-4
- Dirkx, E., van Eys, G. J. J. M., Schwenk, R. W., Steinbusch, L. K. M., Hoebers, N., Coumans, W. A., Peters, T., Janssen, B. J., Brans, B., Vogg, A. T., Neumann, D., Glatz, J. F. C., & Luiken, J. J. F. P. (2014). Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance. Journal of Molecular and Cellular Cardiology, 76, 208-217. https://doi.org/10.1016/j.yjmcc.2014.08.017