• 2019
    • Ferreira, J. P., Verdonschot, J., Collier, T., Wang, P., Pizard, A., Bar, C., Bjorkman, J., Boccanelli, A., Butler, J., Clark, A., Cleland, J. G., Delles, C., Diez, J., Girerd, N., Gonzalez, A., Hazebroek, M., Huby, A.-C., Jukema, W., Latini, R., ... Zannad, F. (2019). Proteomic Bioprofiles and Mechanistic Pathways of Progression to Heart Failure The HOMAGE Study. Circulation-Heart Failure, 12(5), Article 005897. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005897
    • Verjans, R., Derks, W. J. A., Korn, K., Soennichsen, B., van Leeuwen, R. E. W., Schroen, B., van Bilsen, M., & Heymans, S. (2019). Functional Screening Identifies MicroRNAs as Multi-Cellular Regulators of Heart Failure. Scientific Reports, 9(1), Article 6055. https://doi.org/10.1038/s41598-019-41491-9
    • Deckx, S., Johnson, D. M., Rienks, M., Carai, P., Van Deel, E., Van der Velden, J., Sipido, K. R., Heymans, S., & Papageorgiou, A.-P. (2019). Extracellular SPARC increases cardiomyocyte contraction during health and disease. PLOS ONE, 14(4), Article 0209534. https://doi.org/10.1371/journal.pone.0209534
    • Gingele, A. J., Brunner-la Rocca, H., Ramaekers, B., Gorgels, A., De Weerd, G., Kragten, J., van Empel, V., Brandenburg, V., Vrijhoef, H., Cleuren, G., Knackstedt, C., & Boyne, J. J. J. (2019). Telemonitoring in patients with heart failure: Is there a long-term effect?Journal of Telemedicine and Telecare, 25(3), 158-166. https://doi.org/10.1177/1357633x17747641
    • Zhang, M., Moalin, M., Vervoort, L., Li, Z. W., Wu, W. B., & Haenen, G. (2019). Connecting Western and Eastern Medicine from an Energy Perspective. International journal of molecular sciences, 20(6), Article 1512. https://doi.org/10.3390/ijms20061512
    • Calore, M., Lorenzon, A., Vitiello, L., Poloni, G., Khan, M. A. F., Beffagna, G., Dazzo, E., Sacchetto, C., Polishchuk, R., Sabatelli, P., Doliana, R., Carnevale, D., Lembo, G., Bonaldo, P., De Windt, L., Braghetta, P., & Rampazzo, A. (2019). A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt signalling and miRNA dysregulation. Cardiovascular Research, 115(4), 739-751. https://doi.org/10.1093/cvr/cvy253
    • Posthuma, J. J., Posma, J. J. N., van Oerle, R., Leenders, P., van Gorp, R. H., Jaminon, A. M. G., Mackman, N., Heitmeier, S., Schurgers, L. J., ten Cate, H., & Spronk, H. M. H. (2019). Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Scientific Reports, 9(1), Article 3909. https://doi.org/10.1038/s41598-019-40602-w
    • Raso, A., Dirkx, E., Philippen, L. E., Fernandez-Celis, A., De Majo, F., Sampaio-Pinto, V., Sansonetti, M., Juni, R., el Azzouzi, H., Calore, M., Bitsch, N., Olieslagers, S., Oerlemans, M. I. F. J., Huibers, M. M., de Weger, R. A., Reckman, Y. J., Pinto, Y. M., Zentilin, L., Zacchigna, S., ... De Windt, L. J. (2019). Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure. Molecular Therapy, 27(3), 584-599. https://doi.org/10.1016/j.ymthe.2018.11.011
    • Rech, M., Kuhn, A. R., Lumens, J., Carai, P., van Leeuwen, R., Verhesen, W., Verjans, R., Lecomte, J., Liu, Y., Luiken, J. J. F. P., Mohren, R., Cillero-Pastor, B., Heymans, S., Knoops, K., van Bilsen, M., & Schroen, B. (2019). AntagomiR-103 and-107 Treatment Affects Cardiac Function and Metabolism. Molecular Therapy - Nucleic Acids, 14, 424-437. https://doi.org/10.1016/j.omtn.2018.12.010
    • Leicht, L., Skobel, E., Knackstedt, C., Mathissen, M., Sitter, A., Wartzek, T., Moehler, W., Reith, S., Leonhardt, S., & Teichmann, D. (2019). Capacitive ECG Monitoring in Cardiac Patients During Simulated Driving. Ieee Transactions on Biomedical Engineering, 66(3), 749-758. https://doi.org/10.1109/TBME.2018.2855661
    • Koetsier, E., Franken, G., Debets, J., van Kuijk, S. M. J., Perez, R. S. G. M., Linderoth, B., Joosten, E. A. J., & Maino, P. (2019). Effectiveness of dorsal root ganglion stimulation and dorsal column spinal cord stimulation in a model of experimental painful diabetic polyneuropathy. CNS Neuroscience & Therapeutics, 25(3), 367-374. https://doi.org/10.1111/cns.13065
    • de Boer, R. A., De Keulenaer, G., Bauersachs, J., Brutsaert, D., Cleland, J. G., Diez, J., Du, X.-J., Ford, P., Heinzel, F. R., Lipson, K. E., McDonagh, T., Lopez-Andres, N., Lunde, I. G., Lyon, A. R., Pollesello, P., Prasad, S. K., Tocchetti, C. G., Mayr, M., Sluijter, J. P. G., ... Heymans, S. (2019). Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology. European journal of heart failure, 21(3), 272-285. https://doi.org/10.1002/ejhf.1406
    • Aimo, A., Januzzi, J. L., Vergaro, G., Ripoli, A., Latini, R., Masson, S., Magnoli, M., Anand, I. S., Cohn, J. N., Tavazzi, L., Tognoni, G., Gravning, J., Ueland, T., Nymo, S. H., Brunner-La Rocca, H.-P., Bayes-Genis, A., Lupon, J., de Boer, R. A., Yoshihisa, A., ... Emdin, M. (2019). High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure. International Journal of Cardiology, 277, 166-172. https://doi.org/10.1016/j.ijcard.2018.10.079
    • Mullens, W., Damman, K., Harjola, V.-P., Mebazaa, A., Brunner-La Rocca, H.-P., Martens, P., Testani, J. M., Tang, W. H. W., Orso, F., Rossignol, P., Metra, M., Filippatos, G., Seferovic, P. M., Ruschitzka, F., & Coats, A. J. (2019). The use of diuretics in heart failure with congestion - a position statement from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 21(2), 137-155. https://doi.org/10.1002/ejhf.1369
    • Reinhold, S., & Blankesteijn, W. M. (2019). Wnt/β-Catenin Inhibitor Dickkopf 1: A Novel Predictor for Cardiovascular and Cerebrovascular Events. Arteriosclerosis Thrombosis and Vascular Biology, 39(2), 121-123. https://doi.org/10.1161/atvbaha.118.312144
    • Zhong, X., Zhang, Z., Wang, S., Cao, L., Zhou, L., Sun, A., Zhong, Z., & Nabben, M. (2019). Microbial-Driven Butyrate Regulates Jejunal Homeostasis in Piglets During the Weaning Stage. Frontiers in microbiology, 9, Article 3335. https://doi.org/10.3389/fmicb.2018.03335
    • Breetveld, N. M., Ghossein-Doha, C., Van Neer, J., Sengers, M. J. J. M., Geerts, L., Van Kuijk, S. M. J., Van Dijk, A. P., Van Der Vlugt, M. J., Heidema, W. M., Brunner-La Rocca, H. P., Scholten, R. R., & Spaanderman, M. E. A. (2019). Decreased Endothelial Function and Increased Subclinical Heart Failure in Women Several Years after Pre-eclampsia. Obstetrical & Gynecological Survey, 74(1), 13-15. https://doi.org/10.1097/01.ogx.0000550509.43053.d7
    • van Mourik, M. J. W., Zaar, D. V. J., Smulders, M. W., Heijman, J., Lumens, J., Dokter, J. E., Passos, V. L., Schalla, S., Knackstedt, C., Schummers, G., Gjesdal, O., Edvardsen, T., & Bekkers, S. C. A. M. (2019). Adding Speckle-Tracking Echocardiography to Visual Assessment of Systolic Wall Motion Abnormalities Improves the Detection of Myocardial Infarction. Journal of the American Society of Echocardiography, 32(1), 65-73. https://doi.org/10.1016/j.echo.2018.09.007
    • Duygu, B., Juni, R., Ottaviani, L., Bitsch, N., Wit, J. B. M., de Windt, L. J., & Martins, P. A. D. C. (2019). Comparison of different chemically modified inhibitors of miR-199b in vivo. Biochemical Pharmacology, 159, 106-115. https://doi.org/10.1016/j.bcp.2018.11.013
    • Brunner-La Rocca, H.-P., Linssen, G. C., Smeele, F. J., van Drimmelen, A. A., Schaafsma, H.-J., Westendorp, P. H., Rademaker, P. C., van de Kamp, H. J., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2019). Contemporary Drug Treatment of Chronic Heart Failure With Reduced Ejection Fraction The CHECK-HF Registry. JACC: Heart Failure, 7(1), 13-21. https://doi.org/10.1016/j.jchf.2018.10.010
    • Ali, T., Mushtaq, I., Maryam, S., Farhan, A., Saba, K., Jan, M. I., Sultan, A., Anees, M., Duygu, B., Hamera, S., Tabassum, S., Javed, Q., Martin, P. A. D. C., & Murtaza, I. (2019). Interplay of N- acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs. Archives of Biochemistry and Biophysics, 661, 56-65. https://doi.org/10.1016/j.abb.2018.11.007
    • Simonavicius, J., Knackstedt, C., & Brunner-La Rocca, H.-P. (2019). Loop diuretics in chronic heart failure: how to manage congestion?Heart Failure Reviews, 24(1), 17-30. https://doi.org/10.1007/s10741-018-9735-7
    • Verdonschot, J. A. J., Cooper, L. T., & Heymans, S. R. B. (2019). Parvovirus B19 in Dilated Cardiomyopathy: There Is More Than Meets the Eye. Journal of Cardiac Failure, 25(1), 64-66. https://doi.org/10.1016/j.cardfail.2018.11.017
    • Eurlings, C. G. M. J., Boyne, J. J., de Boer, R. A., & Brunner-La Rocca, H. P. (2019). Telemedicine in heart failure-more than nice to have?Netherlands Heart Journal, 27(1), 5-15. https://doi.org/10.1007/s12471-018-1202-5
    • Giamouridis, D., Gao, M. H., Lai, N. C., Tan, Z., Kim, Y. C., Guo, T., Miyanohara, A., Blankesteijn, M. W., Biessen, E. A. L., & Hammond, H. K. (2019). Urocortin 3 Gene Transfer Increases Function of the Failing Murine Heart. Human Gene Therapy, 30(1), 10-20. https://doi.org/10.1089/hum.2018.103
    • Brunner-La Rocca, H., & Sanders - van Wijk, S. (2019). Natriuretic Peptides in Chronic Heart Failure. Cardiac Failure Review, 5(1), 44-49. https://doi.org/10.15420/cfr.2018.26.1
  • 2018
    • Maack, C., Lehrke, M., Backs, J., Heinzel, F. R., Hulot, J.-S., Marx, N., Paulus, W. J., Rossignol, P., Taegtmeyer, H., Bauersachs, J., Bayes-Genis, A., Brutsaert, D., Bugger, H., Clarke, K., Cosentino, F., De Keulenaer, G., Dei Cas, A., Gonzalez, A., Huelsmann, M., ... Heymans, S. (2018). Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology. European Heart Journal, 39(48), 4243–4254. https://doi.org/10.1093/eurheartj/ehy596
    • Steklov, M., Pandolf, S., Baietti, M. F., Batiuk, A., Carai, P., Najm, P., Zhang, M., Jang, H., Renzi, F., Cai, Y., Asbagh, L. A., Pastor, T., De Troyer, M., Simicek, M., Radaelli, E., Brems, H., Legius, E., Tavernier, J., Gevaert, K., ... Sablina, A. A. (2018). Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination. Science, 362(6419), 1177-1182. https://doi.org/10.1126/science.aap7607
    • Rienks, M., Carai, P., van Teeffelen, J., Eskens, B., Verhesen, W., Hemmeryckx, B., Johnson, D. M., van Leeuwen, R., Jones, E. A., Heymans, S., & Papageorgiou, A.-P. (2018). SPARC preserves endothelial glycocalyx integrity, and protects against adverse cardiac inflammation and injury during viral myocarditis. Matrix Biology, 74, 21-34. https://doi.org/10.1016/j.matbio.2018.04.015
    • Brunner-La Rocca, H.-P., & Sanders-van Wijk, S. (2018). Guiding Heart Failure Therapy After GUIDE-IT Back to the Drawing Board. Journal of the American College of Cardiology, 72(21), 2563-2566. https://doi.org/10.1016/j.jacc.2018.08.2185
    • Emdin, M., Aimo, A., Vergaro, G., Bayes-Genis, A., Lupon, J., Latini, R., Meessen, J., Anand, I. S., Cohn, J. N., Gravning, J., Gullestad, L., Broch, K., Ueland, T., Nymo, S. H., Rocca, H.-P. B.-L., de Boer, R. A., Gaggin, H. K., Ripoli, A., Passino, C., & Januzzi, J. L. (2018). sST2 Predicts Outcome in Chronic Heart Failure Beyond N-proBNP and High-Sensitivity Troponin T. Journal of the American College of Cardiology, 72(19), 2309-2320. https://doi.org/10.1016/j.jacc.2018.08.2165
    • Emans, T. W., Patinha, D., Joles, J. A., Koeners, M. P., Janssen, B. J., & Krediet, C. T. P. (2018). Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation. Scientific Reports, 8(1), Article 16342. https://doi.org/10.1038/s41598-018-34211-2
    • Brandao, S. M., Rezende, P. C., Brunner-La Rocca, H.-P., Ju, Y. T., de Lima, A. C., Takiuti, M. E., Hueb, W., & Bocchi, E. A. (2018). Comparative cost-effectiveness of surgery, angioplasty, or medical therapy in patients with multivessel coronary artery disease: MASS II trial. Cost Effectiveness and Resource Allocation, 16(1), Article 55. https://doi.org/10.1186/s12962-018-0158-z
    • Steinmann, E., Rocca, H.-P. B.-L., Maeder, M. T., Kaufmann, B. A., Pfisterer, M., & Rickenbacher, P. (2018). Is the clinical presentation of chronic heart failure different in elderly versus younger patients and those with preserved versus reduced ejection fraction?European journal of internal medicine, 57, 61-69. https://doi.org/10.1016/j.ejim.2018.06.005
    • Verdonschot, J. A. J., Hazebroek, M. R., Wang, P., Sanders-van Wijk, S., Merken, J. J., Adriaansen, Y. A., van den Wijngaard, A., Krapels, I. P. C., Brunner-La Rocca, H.-P., Brunner, H. G., & Heymans, S. R. B. (2018). Clinical Phenotype and Genotype Associations With Improvement in Left Ventricular Function in Dilated Cardiomyopathy. Circulation-Heart Failure, 11(11), Article 005220. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005220
    • el Azzouzi, H., & De Windt, L. J. (2018). If you like it, put a ring on it!Cardiovascular Research, 114(12), 1575-1577. https://doi.org/10.1093/cvr/cvy190
    • Bocchi, E. A., da Cruz, F. D. D., Brandao, S. M., Issa, V., Ayub-Ferreira, S. M., la Rocca, H.-P. B., & van Wijk, S. S. (2018). Cost-Effectiveness Benefits of a Disease Management Program: The REMADHE Trial Results. Journal of Cardiac Failure, 24(10), 627-637. https://doi.org/10.1016/j.cardfail.2018.04.008
    • Foulquier, S., Namsolleck, P., Van Hagen, B. T., Milanova, I., Post, M. J., Blankesteijn, W. M., Rutten, B. P., Prickaerts, J., Van Oostenbrugge, R. J., & Unger, T. (2018). Hypertension-induced cognitive impairment: insights from prolonged angiotensin II infusion in mice. Hypertension Research, 41(10), 817-827. https://doi.org/10.1038/s41440-018-0090-9
    • Merken, J., Brunner-La Rocca, H.-P., Weerts, J., Verdonschot, J., Hazebroek, M., Schummers, G., Schreckenberg, M., Lumens, J., Heymans, S., & Knackstedt, C. (2018). Heart Failure With Recovered Ejection Fraction. Journal of the American College of Cardiology, 72(13), 1556-1557. https://doi.org/10.1016/j.jacc.2018.06.070
    • Smulders, M. W., Bekkers, S. C. A. M., van Cauteren, Y. J. M., Liefhebber, A., Vermeer, J. R., Vervuurt, J., van Dieijen-Visser, M. P., Mingels, A. M. A., Rocca, H.-P. B.-L., Dagnelie, P. C., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Risk stratification and role for additional diagnostic testing in patients with acute chest pain and normal high-sensitivity cardiac troponin levels. PLOS ONE, 13(9), Article e0203506. https://doi.org/10.1371/journal.pone.0203506
    • Mohseni, Z., Spaanderman, M. E. A., Oben, J., Calore, M., Derksen, E., Al-Nasiry, S., De Windt, L. J., & Ghossein-Doha, C. (2018). Cardiac remodeling and pre-eclampsia: an overview of microRNA expression patterns. Ultrasound in Obstetrics & Gynecology, 52(3), 310-317. https://doi.org/10.1002/uog.17516
    • Vasques-Novoa, F., Laundos, T. L., Cerqueira, R. J., Quina-Rodrigues, C., Soares-dos-Reis, R., Baganha, F., Ribeiro, S., Mendonca, L., Goncalves, F., Reguenga, C., Verhesen, W., Carneiro, F., Paiva, J. A., Schroen, B., Castro-Chaves, P., Pinto-do-O, P., Nascimento, D. S., Heymans, S., Leite-Moreira, A. F., & Roncon-Albuquerque, R. (2018). MicroRNA-155 Amplifies Nitric Oxide/cGMP Signaling and Impairs Vascular Angiotensin II Reactivity in Septic Shock. Critical Care Medicine, 46(9), E945-E954. https://doi.org/10.1097/CCM.0000000000003296
    • De Majo, F., & De Windt, L. J. (2018). RNA therapeutics for heart disease. Biochemical Pharmacology, 155, 468-478. https://doi.org/10.1016/j.bcp.2018.07.037
    • Damanafshan, A., Elzenaar, I., Samson-Couterie, B., van der Made, I., Bourajjaj, M., van den Hoogenhof, M. M., van Veen, H. A., Picavet, D. I., Beqqali, A., Ehler, E., DeWindt, L. J., Pinto, Y. M., & van Oort, R. J. (2018). The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy. Cardiovascular Research, 114(11), 1474-1486. https://doi.org/10.1093/cvr/cvy091
    • Vangrieken, P., Al-Nasiry, S., Janssen, G. M. J., Weseler, A. R., Spaanderman, M. E., Bast, A., & Schiffers, P. M. H. (2018). The direct and sustained consequences of severe placental hypoxia on vascular contractility. PLOS ONE, 13(8), Article e0202648. https://doi.org/10.1371/journal.pone.0202648
    • Zhang, M., Vervoort, L., Moalin, M., Mommers, A., Douny, C., den Hartog, G. J. M., & Haenen, G. R. M. M. (2018). The chemical reactivity of (-)-epicatechin quinone mainly resides in its Bring. Free Radical Biology and Medicine, 124, 31-39. https://doi.org/10.1016/j.freeradbiomed.2018.05.087
    • Caolo, V., Roblain, Q., Lecomte, J., Carai, P., Peters, L., Cuijpers, I., Robinson, E. L., Derks, K., Sergeys, J., Noel, A., Jones, E. A. V., Moons, L., & Heymans, S. (2018). Resistance to retinopathy development in obese, diabetic and hypertensive ZSF1 rats: an exciting model to identify protective genes. Scientific Reports, 8(1), Article 11922. https://doi.org/10.1038/s41598-018-29812-w
    • van Empel, V., & Brunner-La Rocca, H.-P. (2018). Helping to understand heart failure with preserved ejection fraction. European Heart Journal, 39(30), 2836-2838. https://doi.org/10.1093/eurheartj/ehy368
    • Emans, T. W., Janssen, B. J., Joles, J. A., & Krediet, C. T. P. (2018). Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats. Journal of the American Heart Association, 7(15), Article 009501. https://doi.org/10.1161/JAHA.118.009501