• 2016
    • Kuklik, P., Schaeffer, B., Hoffmann, B. A., Ganesan, A. N., Schreiber, D., Moser, J. M., Akbulak, R. O., Sultan, A., Steven, D., Maesen, B., Schotten, U., Meyer, C., & Willems, S. (2016). Local Electrical Dyssynchrony during Atrial Fibrillation: Theoretical Considerations and Initial Catheter Ablation Results. PLOS ONE, 11(10), Article e0164236. https://doi.org/10.1371/journal.pone.0164236
    • Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., Hindricks, G., Manolis, A. S., Oldgren, J., Popescu, B. A., Schotten, U., Van Putte, B., & Vardas, P. (2016). 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Heart Journal, 37(38), 2893-2962. https://doi.org/10.1093/eurheartj/ehw210
    • Saporito, S., van Assen, H. C., Houthuizen, P., Aben, J.-P. M. M., Strik, M., van Middendorp, L. B., Prinzen, F. W., & Mischi, M. (2016). Assessment of left ventricular mechanical dyssynchrony in left bundle branch block canine model: Comparison between cine and tagged MRI. Journal of Magnetic Resonance Imaging, 44(4), 956-963. https://doi.org/10.1002/jmri.25225
    • Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Henry, R. M. A., Reesink, K. D., Kroon, A. A., Koster, A., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2016). Carotid stiffness is associated with impairment of cognitive performance in individuals with and without type 2 diabetes. The Maastricht Study. Atherosclerosis, 253, 186-193. https://doi.org/10.1016/j.atherosclerosis.2016.07.912
    • Lemkes, J. S., Janssens, G. N., Oudemans-van Straaten, H. M., Elbers, P. W., van der Hoeven, N. W., Tijssen, J. G. P., Otterspoor, L. C., Voskuil, M., van der Heijden, J. J., Meuwissen, M., Rijpstra, T. A., Vlachojannis, G. J., van der Vleugel, R. M., Nieman, K., Jewbali, L. S. D., Sleeker, G. B., Baak, R., Beishuizen, B., Stoel, M. G., ... van Royen, N. (2016). Coronary angiography after cardiac arrest: Rationale and design of the COACT trial. American Heart Journal, 180, 39-45. https://doi.org/10.1016/j.ahj.2016.06.025
    • Dupuis, L. J., Lumens, J., Arts, T., & Delhaas, T. (2016). Mechano-chemical Interactions in Cardiac Sarcomere Contraction: A Computational Modeling Study. PLoS Computational Biology, 12(10). https://doi.org/10.1371/journal.pcbi.1005126
    • Gelsomino, S., La Meir, M., van Breugel, H. N. A. M., Renzulli, A., Rostagno, C., Lorusso, R., Parise, O., Lozekoot, P. W. J., Klop, I. D. G., Kumar, N., Luca, F., Matteucci, F., Serraino, F., Sante, P., Caciolli, S., Vizzardi, E., De Jong, M., Crijns, H. J. G. M., Gensini, G. F., & Maessen, J. G. (2016). Surgical ablation in patients undergoing mitral valve surgery: impact of lesion set and surgical techniques on long-term success. EP Europace, 18(10), 1528-1537. https://doi.org/10.1093/europace/euv402
    • Heijman, J., Schirmer, I., & Dobrev, D. (2016). The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling. EP Europace, 18(10), 1452-1454. https://doi.org/10.1093/europace/euv417
    • Keijsers, J. M. T., Leguy, C. A. D., Huberts, W., Narracott, A. J., Rittweger, J., & van de Vosse, F. N. (2016). Global sensitivity analysis of a model for venous valve dynamics. Journal of Biomechanics, 49(13), 2845-2853. https://doi.org/10.1016/j.jbiomech.2016.06.029
    • Summer, G., Kelder, T., Radonjic, M., van Bilsen, M., Wopereis, S., & Heymans, S. (2016). The Network Library: a framework to rapidly integrate network biology resources. Bioinformatics, 32(17), 473-478. https://doi.org/10.1093/bioinformatics/btw436
    • van Mil, A., Greyling, A., Zock, P. L., Geleijnse, J. M., Hopman, M. T., Mensink, R. P., Reesink, K. D., Green, D. J., Ghiadoni, L., & Thijssen, D. H. (2016). Impact of volunteer-related and methodology-related factors on the reproducibility of brachial artery flow-mediated vasodilation: analysis of 672 individual repeated measurements. Journal of Hypertension, 34(9), 1738-1745. https://doi.org/10.1097/HJH.0000000000001012
    • Van Gelder, I. C., Rienstra, M., Crijns, H. J. G. M., & Olshansky, B. (2016). Rate control in atrial fibrillation. Lancet, 388(10046), 818-828. https://doi.org/10.1016/S0140-6736(16)31258-2
    • Verdurmen, K., Lempersz, C., Vullings, R., Schroer, C., Delhaas, T., van Laar, J. O. E. H., & Oei, S. G. (2016). Normal ranges for fetal electrocardiogram values for the healthy fetus of 18-24 weeks of gestation: a prospective cohort study. BMC Pregnancy and Childbirth, 16(1), Article 227. https://doi.org/10.1186/s12884-016-1021-x
    • Eck, V. G., Donders, W. P., Sturdy, J., Feinberg, J., Delhaas, T., Hellevik, L. R., & Huberts, W. (2016). A guide to uncertainty quantification and sensitivity analysis for cardiovascular applications. International Journal for Numerical Methods in Biomedical Engineering, 32(8), Article e02755. https://doi.org/10.1002/cnm.2755
    • Holtackers, R. J., Spronck, B., Heusinkveld, M. H. G., Crombag, G., op het Roodt, J., Delhaas, T., Kooi, E., Reesink, K. D., & Hermeling, E. (2016). Head orientation should be considered in ultrasound studies on carotid artery distensibility. Journal of Hypertension, 34(8), 1551-1555. https://doi.org/10.1097/HJH.0000000000000985
    • Zanon, F., Marcantoni, L., Baracca, E., Pastore, G., Lanza, D., Fraccaro, C., Picariello, C., Conte, L., Aggio, S., Roncon, L., Pacetta, D., Badie, N., Noventa, F., & Prinzen, F. W. (2016). Optimization of left ventricular pacing site plus multipoint pacing improves remodeling and clinical response to cardiac resynchronization therapy at 1 year. Heart Rhythm, 13(8), 1644-1651. https://doi.org/10.1016/j.hrthm.2016.05.015
    • Engels, E. B., Mafi-Rad, M., van Stipdonk, T., Vernooy, K., & Prinzen, F. W. (2016). Why QRS Duration Should Be Replaced by Better Measures of Electrical Activation to Improve Patient Selection for Cardiac Resynchronization Therapy. Journal of Cardiovascular Translational Research, 9(4), 257-265. https://doi.org/10.1007/s12265-016-9693-1
    • Boriani, G., Laroche, C., Diemberger, I., Popescu, M. I., Rasmussen, L. H., Petrescu, L., Crijns, H. J. G. M., Tavazzi, L., Maggioni, A. P., & Lip, G. Y. H. (2016). Glomerular filtration rate in patients with atrial fibrillation and 1-year outcomes. Scientific Reports, 6, Article 30271. https://doi.org/10.1038/srep30271
    • Loeffen, R. A., van Oerle, R., Leers, M. P. G., Kragten, J. A., Crijns, H., Spronk, H. M. H., & ten Cate, H. (2016). Factor XIa and Thrombin Generation Are Elevated in Patients with Acute Coronary Syndrome and Predict Recurrent Cardiovascular Events. PLOS ONE, 11(7), Article e0158355. https://doi.org/10.1371/journal.pone.0158355
    • Smulders, M. W., Kietselaer, B. L. J. H., Schalla, S., Bucerius, J., Jaarsma, C., van Dieijen-Visser, M. P., Mingels, A. M. A., Brunner-La Rocca, H., Post, M., Das, M., Crijns, H. J. G. M., Wildberger, J. E., & Bekkers, B. (2016). Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging?American Heart Journal, 177, 102-111. https://doi.org/10.1016/j.ahj.2016.03.025
    • Tan, I., Spronck, B., Kiat, H., Barin, E., Reesink, K. D., Delhaas, T., Avolio, A. P., & Butlin, M. (2016). Heart Rate Dependency of Large Artery Stiffness. Hypertension, 68(1), 236-242. https://doi.org/10.1161/HYPERTENSIONAHA.116.07462
    • Vegh, E. M., Engels, E. B., van Deursen, C. J. M., Merkely, B., Vernooy, K., Singh, J. P., & Prinzen, F. W. (2016). T-wave area as biomarker of clinical response to cardiac resynchronization therapy. EP Europace, 18(7), 1077-1085. https://doi.org/10.1093/europace/euv259
    • Claes, G. R. F., van Tienen, F. H. J., Lindsey, P., Krapels, I. P. C., van den Enden, A., Hoos, M., Barrois, Y. E. G., Janssen, J., Paulussen, A. D. C., Sels, J.-W. E. M., Kuijpers, S. H. H., van Tintelen, J. P., van den Berg, M. P., Heesen, W. F., Garcia-Pavia, P., Perrot, A., Christiaans, I., Salemink, S., Marcelis, C. L. M., ... van den Wijngaard, A. (2016). Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers. European Heart Journal, 37(23), 1815-1822. https://doi.org/10.1093/eurheartj/ehv522
    • Linz, D., Hohl, M., Dhein, S., Ruf, S., Reil, J.-C., Kabiri, M., Wohlfart, P., Verheule, S., Boehm, M., Sadowski, T., & Schotten, U. (2016). Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats. Cardiovascular Research, 110(3), 371-380. https://doi.org/10.1093/cvr/cvw071
    • Zwanenburg, A., Hermans, B. J. M., Andriessen, P., Niemarkt, H. J., Jellema, R. K., Ophelders, D. R. M. G., Vullings, R., Wolfs, T. G. A. M., Kramer, B. W., & Delhaas, T. (2016). Comparison of ECG-based physiological markers for hypoxia in a preterm ovine model. Pediatric Research, 79(6), 907-915. https://doi.org/10.1038/pr.2016.21
    • Ophelders, D. R. M. G., Wolfs, T. G. A. M., Jellema, R. K., Zwanenburg, A., Andriessen, P., Delhaas, T., Ludwig, A.-K., Radtke, S., Peters, V., Janssen, L., Giebel, B., & Kramer, B. W. (2016). Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia. Stem Cells Translational Medicine, 5(6), 754-763. https://doi.org/10.5966/sctm.2015-0197
    • Baumert, M., Porta, A., Vos, M. A., Malik, M., Couderc, J.-P., Laguna, P., Piccirillo, G., Smith, G. L., Tereshchenko, L. G., & Volders, P. G. A. (2016). QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular Electrophysiology. EP Europace, 18(6), 925-944. https://doi.org/10.1093/europace/euv405
    • Reilly, S. N., Liu, X., Carnicer, R., Recalde, A., Muszkiewicz, A., Jayaram, R., Carena, M. C., Wijesurendra, R., Stefanini, M., Surdo, N. C., Lomas, O., Ratnatunga, C., Sayeed, R., Krasopoulos, G., Rajakumar, T., Bueno-Orovio, A., Verheule, S., Fulga, T. A., Rodriguez, B., ... Casadei, B. (2016). Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase. Science Translational Medicine, 8(340), Article 340ra74. https://doi.org/10.1126/scitranslmed.aac4296
    • Lau, D. H., Schotten, U., Mahajan, R., Antic, N. A., Hatem, S. N., Pathak, R. K., Hendriks, J. M. L., Kalman, J. M., & Sanders, P. (2016). Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications. European Heart Journal, 37(20), 1573–1581. https://doi.org/10.1093/eurheartj/ehv375
    • Wellens, H., Lindemans, F. W., Houben, R. P., Gorgels, A., Volders, P. G., ter Bekke, R. M. A., & Crijns, H. J. (2016). Improving survival after out-of-hospital cardiac arrest requires new tools. European Heart Journal, 37(19), 1499-1503. https://doi.org/10.1093/eurheartj/ehv485
    • Vroomen, M., La Meir, M., Crijns, H. J., & Pison, L. (2016). Absence of exit block due to direct capture of the left atrial appendage: A visual confirmation. HeartRhythm Case Reports, 2(3), 268-269. https://doi.org/10.1016/j.hrcr.2015.11.013
    • Heijman, J., & Dobrev, D. (2016). Challenges to the translation of basic science findings to atrial fibrillation therapies. Future Cardiology, 12(3), 251-254. https://doi.org/10.2217/fca-2016-0007
    • Schotten, U., Dobrev, D., Platonov, P. G., Kottkamp, H., & Hindricks, G. (2016). Current controversies in determining the main mechanisms of atrial fibrillation. Journal of Internal Medicine, 279(5), 428-438. https://doi.org/10.1111/joim.12492
    • Upendra Walavalkar, V., Evers, E., Pujar, S., Viralam, K., Maiya, S., Frerich, S., John, C., Rao, S., Reddy, C., Spronck, B., Prinzen, F., Delhaas, T., & Vanagt, W. Y. (2016). Preoperative Sildenafil administration in children undergoing cardiac surgery: a randomized controlled preconditioning study. European Journal of Cardio-Thoracic Surgery, 49(5), 1403-1410. https://doi.org/10.1093/ejcts/ezv353
    • Lankveld, T., de Vos, C. B., Limantoro, I., Zeemering, S., Dudink, E., Crijns, H. J., & Schotten, U. (2016). Systematic analysis of ECG predictors of sinus rhythm maintenance after electrical cardioversion for persistent atrial fibrillation. Heart Rhythm, 13(5), 1020-1027. https://doi.org/10.1016/j.hrthm.2016.01.004
    • Van Gelder, I. C., Hobbelt, A. H., Marcos, E. G., Schotten, U., Cappato, R., Lewalter, T., Schwieler, J., Rienstra, M., & Boriani, G. (2016). Tailored treatment strategies: a new approach for modern management of atrial fibrillation. Journal of Internal Medicine, 279(5), 457-466. https://doi.org/10.1111/joim.12489
    • Wang, Y., Molin, D. G. M., Sevrin, C., Grandfils, C., van den Akker, N. M. S., Gagliardi, M., Knetsch, M. L., Delhaas, T., & Koole, L. (2016). In vitro and in vivo evaluation of drug-eluting microspheres designed for transarterial chemoembolization therapy. International Journal of Pharmaceutics, 503(1-2), 150-162. https://doi.org/10.1016/j.ijpharm.2016.03.002
    • Cardinaels, E. P. M., Altintas, S., Versteylen, M. O., Joosen, I. A., Jellema, L.-J. C., Wildberger, J. E., Das, M., Crijns, H. J., Bekers, O., van Dieijen-Visser, M. P., Kietselaer, B. L., & Mingels, A. M. A. (2016). High-Sensitivity Cardiac Troponin Concentrations in Patients with Chest Discomfort: Is It the Heart or the Kidneys As Well?PLOS ONE, 11(4), Article e0153300. https://doi.org/10.1371/journal.pone.0153300
    • Opacic, D., van Bragt, K. A., Nasrallah, H. M., Schotten, U., & Verheule, S. (2016). Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation. Cardiovascular Research, 109(4), 527-541. https://doi.org/10.1093/cvr/cvw007
    • Heijman, J., Algalarrondo, V., Voigt, N., Melka, J., Wehrens, X. H. T., Dobrev, D., & Nattel, S. (2016). The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis. Cardiovascular Research, 109(4), 467-479. https://doi.org/10.1093/cvr/cvv275
    • Kirchhof, P., Goette, A., Naebauer, M., & Schotten, U. (2016). 12 Jahre AFNET. Vom Forschungsnetzwerk zur Academic Research Organisation. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz, 59(4), 514-522. https://doi.org/10.1007/s00103-016-2323-x
    • Spronck, B., Megens, R. T. A., Reesink, K. D., & Delhaas, T. (2016). A method for three-dimensional quantification of vascular smooth muscle orientation: application in viable murine carotid arteries. Biomechanics and modeling in mechanobiology, 15(2), 419-432. https://doi.org/10.1007/s10237-015-0699-4
    • van Hunnik, A., Lau, D. H., Zeemering, S., Kuiper, M., Verheule, S., & Schotten, U. (2016). Antiarrhythmic effect of vernakalant in electrically remodeled goat atria is caused by slowing of conduction and prolongation of postrepolarization refractoriness. Heart Rhythm, 13(4), 964-972. https://doi.org/10.1016/j.hrthm.2015.12.009
    • ten Sande, J. N., Postema, P. G., Boekholdt, S. M., Tan, H. L., van der Heijden, J. F., de Groot, N. M. S., Volders, P. G. A., Zeppenfeld, K., Boersma, L. V. A., Nannenberg, E. A., Christiaans, I., & Wilde, A. A. M. (2016). Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus. Heart Rhythm, 13(4), 905-912. https://doi.org/10.1016/j.hrthm.2015.12.006
    • Fabritz, L., Guasch, E., Antoniades, C., Bardinet, I., Benninger, G., Betts, T. R., Brand, E., Breithardt, G., Bucklar-Suchankova, G., Camm, A. J., Cartlidge, D., Casadei, B., Chua, W. W., Crijns, H., Deeks, J., Hatem, S., Hidden-Lucet, F., Kääb, S., Maniadakis, N., ... Kirchhof, P. (2016). Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment. Nature Reviews Cardiology, 13(4), 230-237. https://doi.org/10.1038/nrcardio.2015.194
    • Gast, M., Schroen, B., Voigt, A., Haas, J., Kuehl, U., Lassner, D., Skurk, C., Escher, F., Wang, X., Kratzer, A., Michalik, K., Papageorgiou, A., Peters, T., Loebel, M., Wilk, S., Althof, N., Prasanth, K. V., Katus, H., Meder, B., ... Poller, W. (2016). Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity. Journal of Molecular Cell Biology, 8(2), 178-181. https://doi.org/10.1093/jmcb/mjw003
    • Schmidt, C., Wiedmann, F., Voigt, N., Zhou, X.-B., Heijman, J., Lang, S., Albert, V., Kallenberger, S., Ruhparwar, A., Szabo, G., Kallenbach, K., Karck, M., Borggrefe, M., Biliczki, P., Ehrlich, J. R., Baczko, I., Lugenbiel, P., Schweizer, P. A., Donner, B. C., ... Thomas, D. (2016). Response to Letter Regarding Article, "Upregulation of K 2P 3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation". Circulation, 133(11), E440-E441. https://doi.org/10.1161/CIRCULATIONAHA.115.020662
    • Antonopoulos, A. S., Margaritis, M., Verheule, S., Recalde, A., Sanna, F., Herdman, L., Psarros, C., Nasrallah, H., Coutinho, P., Akoumianakis, I., Brewer, A. C., Sayeed, R., Krasopoulos, G., Petrou, M., Tarun, A., Tousoulis, D., Shah, A. M., Casadei, B., Channon, K. M., & Antoniades, C. (2016). Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-gamma/Adiponectin Signalling. Circulation Research, 118(5), 842-855. https://doi.org/10.1161/CIRCRESAHA.115.307856