• 2020
    • Leader, A., ten Cate, V., ten Cate-Hoek, A. J., Beckers, E. A. M., Spectre, G., Giaccherini, C., Gurevich-Shapiro, A., Krashin, E., Raanani, P., Schouten, H. C., Falanga, A., & ten Cate, H. (2020). Anticoagulation in thrombocytopenic patients with hematological malignancy: A multinational clinical vignette-based experiment. European journal of internal medicine, 77, 86-96. https://doi.org/10.1016/j.ejim.2020.03.005
    • Bruggemann, R., Gietema, H., Jallah, B., ten Cate, H., Stehouwer, C., & Spaetgens, B. (2020). Arterial and venous thromboembolic disease in a patient with COVID-19: A case report. Thrombosis Research, 191, 153-155. https://doi.org/10.1016/j.thromres.2020.04.046
    • Ariens, R., Becattini, C., Bender, M., Bergmeier, W., Castoldi, E., Devreese, K., Ellis, M., Gailani, D., Ignjatovic, V., James, P. D., Kerrigan, S., Lambert, M., Lee, L. H., Levi, M., Maugeri, N., Meijers, J., Melero-Martin, J., Michelson, A. D., Mingozzi, F., ... Weisel, J. (2020). Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress. Research and practice in thrombosis and haemostasis, 4(5), 680-713. https://doi.org/10.1002/rth2.12368
    • Tilburg, J., Coenen, D. M., Zirka, G., Dolleman, S., van Oeveren-Rietdijk, A. M., Karel, M. F. A., de Boer, H. C., Cosemans, J. M. E. M., Versteeg, H. H., Morange, P. E., van Vlijmen, B. J. M., Maracle, C. X., & Thomas, G. M. (2020). SLC44A2 deficient mice have a reduced response in stenosis but not in hypercoagulability driven venous thrombosis. Journal of Thrombosis and Haemostasis, 18(7), 1714-1727. https://doi.org/10.1111/jth.14835
    • Li, W., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., Schaper, N. C., Huang, F., Dashtbozorg, B., Tan, T., Zhang, J., Abbasi-Sureshjani, S., Ter Haar Romeny, B. M., Stehouwer, C. D. A., & Houben, A. J. H. M. (2020). Type 2 diabetes and HbA1c are independently associated with wider retinal arterioles: the Maastricht study. Diabetologia, 63(7), 1408-1417. https://doi.org/10.1007/s00125-020-05146-z
    • Bol, M. E., Beurskens, D. M. H., Delnoij, T. S. R., Roekaerts, P. M. H. J., Reutelingsperger, C. P. M., Delhaas, T., van de Poll, M. C. G., Sels, J.-W. E. M., & Nicolaes, G. A. F. (2020). Variability of Microcirculatory Measurements in Critically Ill Patients. Shock, 54(1), 9-14. https://doi.org/10.1097/SHK.0000000000001470
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H.-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), Article 88. https://doi.org/10.1186/s12933-020-01055-y
    • Santovito, D., Egea, V., Bidzhekov, K., Natarelli, L., Mourao, A., Blanchet, X., Wichapong, K., Aslani, M., Brunssen, C., Horckmans, M., Hristov, M., Geerlof, A., Lutgens, E., Daemen, M. J. A. P., Hackeng, T. M., Ries, C., Chavakis, T., Morawietz, H., Naumann, R., ... Weber, C. (2020). Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis. Science Translational Medicine, 12(546), Article 2294. https://doi.org/10.1126/scitranslmed.aaz2294
    • Wynants, L., Van Calster, B., Collins, G. S., Riley, R. D., Heinze, G., Schuit, E., Albu, E., Arshi, B., Bellou, V., Bonten, M. M. J., Dahly, D. L., Damen, J. A., Debray, T. P. A., de Jong, V. M. T., De Vos, M., Dhiman, P., Ensor, J., Gao, S., Haller, M. C., ... van Royen, F. S. (2020). Update to living systematic review (vol 369, m1328, 2020). BMJ, 369, Article m2204. https://doi.org/10.1136/bmj.m2204
    • Pool, R., Hagenbeek, F. A., Hendriks, A. M., van Dongen, J., Willemsen, G., de Geus, E., van Dijk, K. W., Verhoeven, A., Suchiman, H. E., Beekman, M., Slagboom, P. E., Harms, A. C., Hankemeier, T., Boomsma, D. I., Suchiman, H. E. D., Amin, N., Beulens, J. W., van der Bom, J. A., Bomer, N., ... BBMRI Metabolomics Consortium (2020). Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data. Twin Research and Human Genetics, 23(3), 145-155. Article 1832427420000535. https://doi.org/10.1017/thg.2020.53
    • Kaufmann, T., Cox, E. G. M., Wiersema, R., Hiemstra, B., Eck, R. J., Koster, G., Scheeren, T. W. L., Keus, F., Saugel, B., van der Horst, I. C. C., & SICS Study Group (2020). Non-invasive oscillometric versus invasive arterial blood pressure measurements in critically ill patients: A post hoc analysis of a prospective observational study. Journal of Critical Care, 57, 118-123. https://doi.org/10.1016/j.jcrc.2020.02.013
    • van Bergen, M. G. J. M., Saes, J. L., Simons, A., Hebeda, K. M., Henskens, Y. M. C., Barteling, W., Huys, E., Laros-van Gorkom, B. A. P., Schols, S. E. M., Preijers, F. W., Jongmans, M. C. J., Jansen, J. H., & van der Reijden, B. A. (2020). Platelet CD34 expression in a patient with a partial deletion of transcription factor subunit CBFB. American Journal of Hematology, 95(6), E136-E139. https://doi.org/10.1002/ajh.25770
    • den Biggelaar, L. J. C. J., Sep, S. J. S., Mari, A., Ferrannini, E., van Dongen, M. C. J. M., Wijckmans, N. E. G., Schram, M. T., van der Kallen, C. J., Schaper, N., Henry, R. M. A., van Greevenbroek, M. M., Stehouwer, C. D. A., & Eussen, S. J. P. M. (2020). Association of artificially sweetened and sugar-sweetened soft drinks with β-cell function, insulin sensitivity, and type 2 diabetes: the Maastricht Study. European Journal of Nutrition, 59(4), 1717-1727. https://doi.org/10.1007/s00394-019-02026-0
    • Martens, R. J. H., Henry, R. M. A., Bekers, O., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Greevenbroek, M., Kroon, A. A., Stehouwer, C. D. A., Wesselius, A., Meex, S. J. R., & Kooman, J. P. (2020). Associations of 24-Hour Urinary Sodium and Potassium Excretion with Cardiac Biomarkers: The Maastricht Study. Journal of Nutrition, 150(6), 1413-1424. https://doi.org/10.1093/jn/nxaa080
    • Rensma, S. P., Stehouwer, C. D. A., Van Boxtel, M. P. J., Houben, A. J. H. M., Berendschot, T. T. J. M., Jansen, J. F. A., Schalkwijk, C. G., Verhey, F. R. J., Kroon, A. A., Henry, R. M. A., Backes, W. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bosma, H., Köhler, S., Reesink, K. D., Schram, M. T., & van Sloten, T. T. (2020). Associations of Arterial Stiffness With Cognitive Performance, and the Role of Microvascular Dysfunction: The Maastricht Study. Hypertension, 75(6), 1607-1614. https://doi.org/10.1161/hypertensionaha.119.14307
    • Robinson, E. L., Gomes, C. P. C., Potocnjak, I., Hellemans, J., Betsou, F., de Gonzalo-Calvo, D., Stoll, M., Yilmaz, M. B., Agg, B., Beis, D., Carmo-Fonseca, M., Enguita, F. J., Dogan, S., Tuna, B. G., Schroen, B., Ammerlaan, W., Kuster, G. M., Carpusca, I., Pedrazzini, T., ... EU-CardioRNA COST Action (2020). A Year in the Life of the EU-CardioRNA COST Action: CA17129 Catalysing Transcriptomics Research in Cardiovascular Disease. Non-coding RNA, 6(2), Article 17. https://doi.org/10.3390/ncrna6020017
    • Kroone, C., Vos, M., Rademakers, T., Kuijpers, M., Hoogenboezem, M., van Buul, J., Heemskerk, J. W. M., Ruf, W., van Hylckama Vlieg, A., Versteeg, H. H., Goumans, M.-J., de Vries, C. J. M., Kurakula, K., & INVENT Consortium (2020). LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis. Haematologica-the Hematology Journal, 105(6), 1677-1685. https://doi.org/10.3324/haematol.2018.203026
    • Vogelzangs, N., van der Kallen, C. J. H., van Greevenbroek, M. M. J., van der Kolk, B. W., Jocken, J. W. E., Goossens, G. H., Schaper, N. C., Henry, R. M. A., Eussen, S. J. P. M., Valsesia, A., Hankemeier, T., Astrup, A., Saris, W. H. M., Stehouwer, C. D. A., Blaak, E. E., Arts, I. C. W., & CODAM study (2020). Metabolic profiling of tissue-specific insulin resistance in human obesity: results from the Diogenes study and the Maastricht Study. International Journal of Obesity, 44(6), 1376-1386. https://doi.org/10.1038/s41366-020-0565-z
    • Jiritano, F., Serraino, G. F., ten Cate, H., Fina, D., Matteucci, M., Mastroroberto, P., & Lorusso, R. (2020). Platelets and extra-corporeal membrane oxygenation in adult patients: a systematic review and meta-analysis. Intensive Care Medicine, 46(6), 1154-1169. https://doi.org/10.1007/s00134-020-06031-4
    • Visser, M., Heitmeier, S., ten Cate, H., & Spronk, H. M. H. (2020). Role of Factor XIa and Plasma Kallikrein in Arterial and Venous Thrombosis. Thrombosis and Haemostasis, 120(6), 883-993. https://doi.org/10.1055/s-0040-1710013
    • Kaufmann, T., van der Horst, I. C. C., & Scheeren, T. W. L. (2020). This is your toolkit in hemodynamic monitoring. Current Opinion in Critical Care, 26(3), 303-312. https://doi.org/10.1097/MCC.0000000000000727
    • Calzavarini, S., Prince-Eladnani, R., Saller, F., Bologna, L., Burnier, L., Brisset, A. C., Quarroz, C., Caro, M. D. R., Ermolayev, V., Matsumura, Y., Fernandez, J. A., Hackeng, T. M., Griffin, J. H., & Angelillo-Scherrer, A. (2020). Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus. Blood, 135(22), 1969-1982. https://doi.org/10.1182/blood.2019003630
    • Ntalla, I., Weng, L.-C., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., ... Munroe, P. B. (2020). Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications, 11(1), Article 2542. https://doi.org/10.1038/s41467-020-15706-x
    • De Majo, F., Hegenbarth, J.-C., Ruehle, F., Baer, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A.-S., Stoll, M., & De Windt, L. J. (2020). Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts. Scientific Reports, 10(1), Article 8136. https://doi.org/10.1038/s41598-020-65115-9
    • Bavalia, R., Abdoellakhan, R., Brinkman, H. J. M., Brekelmans, M. P. A., Hamulyak, E. N., Zuurveld, M., Hutten, B. A., Westerweel, P. E., Olie, R. H., ten Cate, H., Kruip, M., Middeldorp, S., Meijer, K., & Coppens, M. (2020). Emergencies on direct oral anticoagulants: Management, outcomes, and laboratory effects of prothrombin complex concentrate. Research and practice in thrombosis and haemostasis, 4(4), 569-581. https://doi.org/10.1002/rth2.12336
    • Foreman, Y. D., Brouwers, M. C. G. J., van der Kallen, C. J. H., Pagen, D. M. E., van Greevenbroek, M. M. J., Henry, R. M. A., Koster, A., Wesselius, A., Schaper, N. C., & Stehouwer, C. D. A. (2020). Glucose Variability Assessed with Continuous Glucose Monitoring: Reliability, Reference Values, and Correlations with Established Glycemic Indices-The Maastricht Study. Diabetes Technology & Therapeutics, 22(5), 395-403. https://doi.org/10.1089/dia.2019.0385
    • Cox, E. G. M., Wiersema, R., Wong, A. R., van der Horst, I. C. C., & SICS Study Group (2020). Six versus eight and twenty-eight scan sites for B-line assessment: differences in examination time and findings. Intensive Care Medicine, 46(5), 1063-1064. https://doi.org/10.1007/s00134-020-06004-7
    • Coopmans, C., Zhou, T. L., Henry, R. M. A., Heijman, J., Schaper, N. C., Koster, A., Schram, M. T., van der Kallen, C. J. H., Wesselius, A., den Engelsman, R. J. A., Crijns, H. J. G. M., & Stehouwer, C. D. A. (2020). Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study. Diabetes Care, 43(5), 1126-1133. https://doi.org/10.2337/dc19-2367
    • Beurskens, D. M. H., Bol, M. E., Delhaas, T., van de Poll, M. C. G., Reutelingsperger, C. P. M., Nicolaes, G. A. F., & Sels, J.-W. E. M. (2020). Decreased endothelial glycocalyx thickness is an early predictor of mortality in sepsis. Anaesthesia and Intensive Care, 48(3), 221-228. https://doi.org/10.1177/0310057X20916471
    • Sorensen, B. M., van der Heide, F. C. T., Houben, A. J. H. M., Koster, A., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., van Dongen, M. C. J. M., Eussen, S. J. P. M., Savelberg, H. H. C. M., van der Berg, J. D., Schaper, N. C., Schram, M. T., & Stehouwer, C. D. A. (2020). Higher levels of daily physical activity are associated with better skin microvascular function in type 2 diabetes-The Maastricht Study. Microcirculation, 27(4), Article 12611. https://doi.org/10.1111/micc.12611
    • Ordieres-Ortega, L., Demelo-Rodriguez, P., Galeano-Valle, F., Kremers, B. M. M., ten Cate-Hoek, A. J., & ten Cate, H. (2020). Predictive value of D-dimer testing for the diagnosis of venous thrombosis in unusual locations: A systematic review. Thrombosis Research, 189, 5-12. https://doi.org/10.1016/j.thromres.2020.02.009
    • Notten, P., van Laanen, J. H. H., Eijgenraam, P., de Wolf, M. A. F., Kurstjens, R. L. M., ten Cate, H., & ten Cate-Hoek, A. J. (2020). Quality of anticoagulant therapy and the incidence of in-stent thrombosis after venous stenting. Research and practice in thrombosis and haemostasis, 4(4), 594-603. https://doi.org/10.1002/rth2.12330
    • Benedikter, B. J., & Koenen, R. R. (2020). Vaping, vapor, vesicles! Electronic cigarettes provoke vascular extracellular vesicle release in healthy volunteers. Atherosclerosis, 301, 79-81. https://doi.org/10.1016/j.atherosclerosis.2020.03.012
    • Huang, S., Sanfilippo, F., Herpain, A., Balik, M., Chew, M., Clau-Terre, F., Corredor, C., De Backer, D., Fletcher, N., Geri, G., Mekontso-Dessap, A., McLean, A., Morelli, A., Orde, S., Petrinic, T., Slama, M., van der Horst, I. C. C., Vignon, P., Mayo, P., & Vieillard-Baron, A. (2020). Systematic review and literature appraisal on methodology of conducting and reporting critical-care echocardiography studies: a report from the European Society of Intensive Care Medicine PRICES expert panel. Annals of Intensive Care, 10(1), Article 49. https://doi.org/10.1186/s13613-020-00662-y
    • Wiersema, R., Jukarainen, S., Eck, R. J., Kaufmann, T., Koeze, J., Keus, F., Pettila, V., van der Horst, I. C. C., & Vaara, S. T. (2020). Different applications of the KDIGO criteria for AKI lead to different incidences in critically ill patients: a post hoc analysis from the prospective observational SICS-II study. Critical Care, 24(1), Article 164. https://doi.org/10.1186/s13054-020-02886-7
    • ten Cate, H. (2020). Thrombosis management in times of COVID-19 epidemy; a Dutch perspective. Thrombosis Journal, 18(7), Article 7. https://doi.org/10.1186/s12959-020-00220-3
    • van Dam, L. F., Dronkers, C. E. A., Gautam, G., Eckerbom, Å., Ghanima, W., Gleditsch, J., von Heijne, A., Hofstee, H. M. A., Hovens, M. M. C., Huisman, M. V., Kolman, S., Mairuhu, A. T. A., Nijkeuter, M., van de Ree, M. A., van Rooden, C. J., Westerbeek, R. E., Westerink, J., Westerlund, E., Kroft, L. J. M., ... Hamulyak, K. (2020). Magnetic resonance imaging for diagnosis of recurrent ipsilateral deep vein thrombosis. Blood, 135(16), 1377-1385. https://doi.org/10.1182/blood.2019004114
    • Wiersema, R., Jukarainen, S., Vaara, S. T., Poukkanen, M., Lakkisto, P., Wong, H., Linder, A., van der Horst, I. C. C., & Pettila, V. (2020). Two subphenotypes of septic acute kidney injury are associated with different 90-day mortality and renal recovery. Critical Care, 24(1), Article 150. https://doi.org/10.1186/s13054-020-02866-x
    • d'Alessandro, E., Becker, C., Bergmeier, W., Bode, C., Bourne, J. H., Brown, H., Buller, H. R., ten Cate-Hoek, A. J., ten Cate, V., van Cauteren, Y. J. M., Cheung, Y. F. H., Cleuren, A., Coenen, D., Crijns, H. J. G. M., de Simone, I., Dolleman, S. C., Klein, C. E., Fernandez, D. I., Granneman, L., ... Scientific Reviewer Committee (2020). Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 120(4), 538-564. https://doi.org/10.1055/s-0040-1708035
    • Wynants, L., Van Calster, B., Collins, G. S., Riley, R. D., Heinze, G., Schuit, E., Bonten, M. M. J., Dahly, D. L., Damen, J. A. A., Debray, T. P. A., de Jong, V. M. T., De Vos, M., Dhiman, P., Haller, M. C., Harhay, M. O., Henckaerts, L., Heus, P., Kammer, M., Kreuzberger, N., ... van Smeden, M. (2020). Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal. BMJ, 369, Article m1328. https://doi.org/10.1136/bmj.m1328
    • Eckardt, V., Miller, M. C., Blanchet, X., Duan, R., Leberzammer, J., Duchene, J., Soehnlein, O., Megens, R. T. A., Ludwig, A.-K., Dregni, A., Faussner, A., Wichapong, K., Ippel, H., Dijkgraaf, I., Kaltner, H., Doering, Y., Bidzhekov, K., Hackeng, T. M., Weber, C., ... Mayo, K. H. (2020). Chemokines and galectins form heterodimers to modulate inflammation. Embo Reports, 21(4), Article 47852. https://doi.org/10.15252/embr.201947852
    • Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H. C., Kaas-Hansen, B. S., van der Horst, I. C. C., Lange, T., Wetterslev, J., Perner, A., & Moller, M. H. (2020). Heterogeneity of treatment effect of prophylactic pantoprazole in adult ICU patients: a post hoc analysis of the SUP-ICU trial. Intensive Care Medicine, 46(4), 717-726. https://doi.org/10.1007/s00134-019-05903-8
    • Kowalewski, M., Raffa, G., Zielinski, K., Meani, P., Alanazi, M., Gilbers, M., Heuts, S., Natour, E., Bidar, E., Schreurs, R., Delnoij, T., Driessen, R., Sels, J. W., van de Poll, M., Roekaerts, P., Maessen, J., Suwalski, P., & Lorusso, R. (2020). Baseline surgical status and short-term mortality after extracorporeal membrane oxygenation for post-cardiotomy shock: a meta-analysis. Perfusion, 35(3), 246-254. Article 0267659119865122. https://doi.org/10.1177/0267659119865122
    • Brouns, S. L. N., Provenzale, I., van Geffen, J. P., van der Meijden, P. E. J., & Heemskerk, J. W. M. (2020). Localized endothelial-based control of platelet aggregation and coagulation under flow: A proof-of-principle vessel-on-a-chip study. Journal of Thrombosis and Haemostasis, 18(4), 931-941. https://doi.org/10.1111/jth.14719
    • van Beek, D. E. C., Kuijpers, Y. A. M., Königs, M. H. H., van der Horst, I. C. C., & Scheeren, T. W. L. (2020). Low serum albumin levels and new-onset atrial fibrillation in the ICU: a prospective cohort study. Journal of Critical Care, 56, 26-30. https://doi.org/10.1016/j.jcrc.2019.11.011
    • Keuning, B. E., Kaufmann, T., Wiersema, R., Granholm, A., Pettila, V., Moller, M. H., Christiansen, C. F., Forte, J. C., Snieder, H., Keus, F., Pleijhuis, R. G., van der Horst, I. C. C., & HEALICS consortium (2020). Mortality prediction models in the adult critically ill: A scoping review. Acta Anaesthesiologica Scandinavica, 64(4), 424-442. https://doi.org/10.1111/aas.13527
    • Jessurun, N. T., Wijnen, P. A., Bast, A., van Puijenbroek, E. P., Bekers, O., & Drent, M. (2020). Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers. International journal of molecular sciences, 21(8), Article 2770. https://doi.org/10.3390/ijms21082770
    • Seelig, J., Verheugt, F. W. A., Hemels, M. E. W., Illingworth, L., Lucassen, A., Adriaansen, H., Bongaerts, M. C. M., Pieterse, M., Herrman, J. P. R., Hoogslag, P., Hermans, W., Groenemeijer, B. E., Boersma, L. V. A., Pieper, K., ten Cate, H., & GARFIELD-AF Investigators (2020). Changes in anticoagulant prescription in Dutch patients with recent-onset atrial fibrillation: observations from the GARFIELD-AF registry. Thrombosis Journal, 18(5), Article 5. https://doi.org/10.1186/s12959-020-00218-x
    • Posma, R. A., Froslev, T., Jespersen, B., van der Horst, I. C. C., Touw, D. J., Thomsen, R. W., Nijsten, M. W., & Christiansen, C. F. (2020). Prognostic impact of elevated lactate levels on mortality in critically ill patients with and without preadmission metformin treatment: a Danish registry-based cohort study. Annals of Intensive Care, 10(1), Article 36. https://doi.org/10.1186/s13613-020-00652-0
    • Salgado, C., Gruis, N., Heijmans, B. T., Oosting, J., van Doorn, R., BIOS Consortium, & Isaacs, A. (2020). Genome-wide analysis of constitutional DNA methylation in familial melanoma. Clinical epigenetics, 12(1), Article 43. https://doi.org/10.1186/s13148-020-00831-7