Publications
- 2025
- Ruthmann, F., Lo, J. W., Mendyk-Bordet, A.-M., Allart, E., Köhler, S., Klimkowicz-Mrowiec, A., Staals, J., Sachdev, P. S., Bordet, R., Dondaine, T., & Stroke and Cognition (STROKOG) Collaboration (2025). Prevalence of poststroke anxiety and its associations with global cognitive impairment: An individual participant data analysis. Journal of Affective Disorders, 369, 1136-1144. https://doi.org/10.1016/j.jad.2024.10.099
- Zhao, H., Xu, Z., Chen, L., Wu, L., Cui, Z., Ma, J., Sun, T., Lei, Y., Wang, N., Hu, H., Tan, Y., Lu, W., Yang, W., Liao, K., Teng, G., Liang, X., Li, Y., Feng, C., Nie, T., ... Zheng, C. (2025). Large-scale pretrained frame generative model enables real-time low-dose DSA imaging: An AI system development and multi-center validation study. Med, 6(1), Article 100497. https://doi.org/10.1016/j.medj.2024.07.025
- Manukjan, N., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2025). Vascular endothelial growth factor: a double-edged sword in the development of white matter lesions. Neural Regeneration Research, 20(1), 191-192. https://doi.org/10.4103/NRR.NRR-D-23-01843
- Nogueira, R. G., Jovin, T. G., Liu, X., Hu, W., Langezaal, L. C. M., Li, C., Dai, Q., Tao, C., Mont'Alverne, F. J. A., Ji, X., Liu, R., Li, R., Dippel, D. W. J., Wu, C., Zhu, W., Xu, P., van Zwam, W. H., Wu, L., Zhang, C., ... ATTENTION, BASICS, BAOCHE, and BEST Investigators (2025). Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis. Lancet, 405(10472), 61-69. https://doi.org/10.1016/S0140-6736(24)01820-8
- van Zwam, W. H., Aguiar de Sousa, D., & Ribo, M. (2025). ESR Bridges: imaging and treatment of cerebral ischaemia-a multidisciplinary view. European Radiology, 35(1), 1-3. https://doi.org/10.1007/s00330-024-10891-5
- Voorter, P. H. M., Jansen, J. F. A., van der Thiel, M. M., van Dinther, M., Postma, A. A., van Oostenbrugge, R. J., Gurney-Champion, O. J., Drenthen, G. S., & Backes, W. H. (2025). Diffusion-derived intravoxel-incoherent motion anisotropy relates to CSF and blood flow. Magnetic Resonance in Medicine, 93(3), 930-941. Advance online publication. https://doi.org/10.1002/mrm.30294
- van Oeteren, M. A. J., Simons, N., Simons, P. I. H. G., van de Waarenburg, M. P. H., Kooi, M. E., Feskens, E. J. M., van der Ploeg, E. M. C. L., Van den Eynde, M. D. G., Houben, A. J. H. M., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). Fructose restriction has beneficial effects on adipose tissue distribution but not on serum adipokine levels: Post-hoc analysis of a double-blind randomized controlled trial. Clinical Obesity, 15(1), Article e12714. Advance online publication. https://doi.org/10.1111/cob.12714
- 2024
- Lee, A., Jere, A., Du Plessis, L., Van Gerven, P. W. M., Heeneman, S., & Ross, S. (2024). Continuity of supervision: Balancing continuous and episodic relationships for assessment and learning. Medical Education. Advance online publication. https://doi.org/10.1111/medu.15595
- Ben-Aicha, S., & van der Vorst, E. P. C. (2024). Shaping the future of cardiovascular research: a focus on cardioimmunology. European Heart Journal, Article ehae783. https://doi.org/10.1093/eurheartj/ehae783
- Voorter, P. H. M., Stringer, M. S., van Dinther, M., Kerkhofs, D., Dewenter, A., Blair, G. W., Thrippleton, M. J., Jaime Garcia, D., Chappell, F. M., Janssen, E., Kopczak, A., Staals, J., Ingrisch, M., Duering, M., Doubal, F. N., Dichgans, M., van Oostenbrugge, R. J., Jansen, J. F. A., Wardlaw, J. M., ... SVDs@target Consortium (2024). Heterogeneity and Penumbra of White Matter Hyperintensities in Small Vessel Diseases Determined by Quantitative MRI. Stroke. Advance online publication. https://doi.org/10.1161/STROKEAHA.124.047910
- van Loon, T., Rijks, J., van Koll, J., Wolffs, J., Cornelussen, R., van Osta, N., Luermans, J., Prinzen, F., Linz, D., van Empel, V., Delhaas, T., Vernooy, K., & Lumens, J. (2024). Accelerated atrial pacing reduces left-heart filling pressure: a combined clinical-computational study. European Heart Journal, 45(46), 4953-4964. https://doi.org/10.1093/eurheartj/ehae718
- Sikking, M. A., Harding, D., Henkens, M. T. H. M., Stroeks, S. L. V. M., Venner, M. F. G. H. M., Nihant, B., van Leeuwen, R. E. W., Fanti, S., Li, X., van Paassen, P., Knackstedt, C., Brunner-la Rocca, H.-P., van Empel, V. P. M., Verdonschot, J. A. J., Marelli-Berg, F. M., & Heymans, S. R. B. (2024). Cytotoxic T-Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy. Circulation Research, 135(12), 1193-1195. https://doi.org/10.1161/CIRCRESAHA.124.325183
- Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Additional value of CTP maps in occlusion detection on CTP angiographic reconstructions for ischemic stroke. European Journal of Radiology, 181, Article 111789. https://doi.org/10.1016/j.ejrad.2024.111789
- Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Angiographic reconstructions of CT perfusion for occlusion detection in ischemic stroke. European Journal of Radiology, 181, Article 111819. https://doi.org/10.1016/j.ejrad.2024.111819
- Ramaekers, M. J. F. G., Te Kiefte, B. J. C., Adriaans, B. P., Juffermans, J. F., van Assen, H. C., Winkens, B., Wildberger, J. E., Lamb, H. J., Schalla, S., & Westenberg, J. J. M. (2024). Comprehensive sex-specific and age-dependent analysis of four-dimensional flow cardiovascular magnetic resonance assessed aortic blood flow-related parameters in normal subjects using single-vendor magnetic resonance systems and single-vendor software. Journal of Cardiovascular Magnetic Resonance, 26(2), Article 101083. https://doi.org/10.1016/j.jocmr.2024.101083
- Achten, A., Muller, S. A., Wijk, S. S., van der Meer, M. G., van der Harst, P., van Tintelen, P., Te Riele, A. S., van Empel, V., Oerlemans, M. I., & Knackstedt, C. (2024). Diversity of heart failure phenotypes in transthyretin amyloid cardiomyopathy. More than just heart failure with preserved ejection fraction. Annals of Medicine, 56(1), Article 2418965. https://doi.org/10.1080/07853890.2024.2418965
- Bleckwehl, T., Babler, A., Tebens, M., Maryam, S., Nyberg, M., Bosteen, M., Halder, M., Shaw, I., Fleig, S., Pyke, C., Hvid, H., Voetmann, L. M., van Buul, J. D., Sluimer, J. C., Das, V., Baumgart, S., Kramann, R., & Hayat, S. (2024). Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis. Nature cardiovascular research. Advance online publication. https://doi.org/10.1038/s44161-024-00582-1
- Cozijnsen, L., Adriaans, B. P., Schermer, T. R., Groenink, M., Schalla, S., & Bekkers, S. C. A. M. (2024). Growth rates in non-syndromic aneurysms of the ascending aorta: a systematic review. Netherlands Heart Journal, 32(12), 433-441. https://doi.org/10.1007/s12471-024-01911-6
- Vermeulen, I., Li, M., van Mourik, H., Yadati, T., Eijkel, G., Balluff, B., Godschalk, R., Temmerman, L., Biessen, E. A. L., Kulkarni, A., Theys, J., Houben, T., Cillero-Pastor, B., & Shiri-Sverdlov, R. (2024). Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis. FEBS Journal. Advance online publication. https://doi.org/10.1111/febs.17358
- Weerts, J., Mourmans, S. G. J., Lopez-Martinez, H., Domingo, M., Aizpurua, A. B., Henkens, M. T. H. M., Achten, A., Lupon, J., Brunner-La Rocca, H.-P., Knackstedt, C., Bayes-Genis, A., & van Empel, V. P. M. (2024). Inter-atrial block as a predictor of adverse outcomes in patients with HFpEF. Esc heart failure. Advance online publication. https://doi.org/10.1002/ehf2.15179
- Ekpenyong, A., Holmboe, E. S., Govaerts, M., & Heeneman, S. (2024). Investigating the Roles and Impact of Clinical Competency Committees in Graduate Medical Education: A Narrative Review. Journal of Graduate Medical Education, 16(6), 662-683. https://doi.org/10.4300/JGME-D-24-00017.1
- Jada, L., Holtackers, R. J., Martens, B., Nies, H. M. J. M., Van De Heyning, C. M., Botnar, R. M., Wildberger, J. E., Ismail, T. F., Razavi, R., & Chiribiri, A. (2024). Quantification of myocardial scar of different etiology using dark- and bright-blood late gadolinium enhancement cardiovascular magnetic resonance. Scientific Reports, 14(1), Article 5395. Advance online publication. https://doi.org/10.1038/s41598-024-52058-8
- Knapen, R. R. M. M., Celen, M., Benali, F., van Oostenbrugge, R. J., van Zwam, W. H., & van der Leij, C. (2024). The use of a (non-) balloon guide catheter in endovascular stroke treatment, a registry of real-life use and nationwide questionnaire. Journal of Stroke & Cerebrovascular Diseases, 33(12), Article 108033. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108033
- Bloch, M. J., Kirtane, A. J., Azizi, M., Mahfoud, F., Basile, J., Daemen, J., Saxena, M., Thackeray, L., McGuire, M., Claude, L., Schmieder, R. E., Kröpil, P., Stegbauer, J., Rump, C., Uder, M., Ott, C., Lucic, J., Ewen, S., Böhm, M., ... RADIANCE-HTN Investigators (2024). 36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO. Hypertension Research, 47(12), 3467-3472. https://doi.org/10.1038/s41440-024-01854-w
- Knapen, R. R. M. M., Olthuis, S. G. H., van Es, A. C. G. M., Emmer, B. J., Schonewille, W. J., van der Leij, C., van Zwam, W. H., van Oostenbrugge, R. J., & MR CLEAN LATE Trial investigators (2024). Association of first-line thrombectomy technique and outcome in late-window large vessel occlusion strokes: A post hoc analysis of the MR CLEAN-LATE trial. International journal of stroke, 19(10), 1113-1122. https://doi.org/10.1177/17474930241268303
- Strbian, D., Tsivgoulis, G., Ospel, J. M., Räty, S., Cimflova, P., Georgiopoulos, G., Ullberg, T., Arquizan, C., Gralla, J., Zelenák, K., Hussain, S., Fiehler, J., Michel, P., Turc, G., & van Zwam, W. (2024). European Stroke Organisation (ESO) and European Society for Minimally Invasive Neurological Therapy (ESMINT) Guideline on Acute Management of Basilar Artery Occlusion. European Stroke Journal, 9(4), 835-884. https://doi.org/10.1177/23969873241257223
- Pinckaers, F. M. E., Grutters, J. P. C., Huijberts, I., Gabrio, A., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Evers, S. M. A. A. (2024). Author's Response to Letter to the Editor Titled "Potential Biases in Post-stroke Health Utility Estimates by Modified Rankin Scale Scores". Value in Health. Advance online publication. https://doi.org/10.1016/j.jval.2024.10.3854
- Heuts, S., Kawczynski, M. J., Leus, A., Godinas, L., Belge, C., van Empel, V., Meyns, B., Maessen, J. G., Delcroix, M., & Verbelen, T. (2024). The volume-outcome relation for pulmonary endarterectomy in chronic thrombo-embolic pulmonary hypertension. European Respiratory Journal. Advance online publication. https://doi.org/10.1183/13993003.01865-2024
- Berends, E., Pencheva, M. G., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2024). Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes. Journal of Physiology, 602(22), 6209-6223. https://doi.org/10.1113/JP286723
- Kral, M., Doering, Y., & Weber, C. (2024). Early intermittent cholesterol exposure accelerates atherosclerosis: an oscillating amplifier calling for preemptive control. Signal Transduction and Targeted Therapy, 9(1), Article 313. https://doi.org/10.1038/s41392-024-02032-7
- Jesser, J., Nguyen, T., Dmytriw, A. A., Yamagami, H., Miao, Z., Sommer, L. J., Stockero, A., Pfaff, J. A. R., Ospel, J., Goyal, M., Patel, A. B., Pereira, V. M., Hanning, U., Meyer, L., van Zwam, W. H., Bendszus, M., Wiesmann, M., Möhlenbruch, M., & Weyland, C. S. (2024). Treatment practice of vasospasm during endovascular thrombectomy: an international survey. Stroke and Vascular Neurology, 9(5), 490-496. https://doi.org/10.1136/svn-2023-002788
- Tobal, R., Potjewijd, J., de Vries, F., van Doorn, D. P. C., Jaminon, A., Bittner, R., Akbulut, C., van Empel, V., Heeringa, P., Damoiseaux, J., Schurgers, L., & van Paassen, P. (2024). Dephosphorylated uncarboxylated Matrix-Gla-Protein as candidate biomarker for immune-mediated vascular remodeling and prognosis in pulmonary hypertension. Scientific Reports, 14(1), Article 26633. https://doi.org/10.1038/s41598-024-77000-w
- Stringer, M. S., Blair, G. W., Kopczak, A., Kerkhofs, D., Thrippleton, M. J., Chappell, F. M., Maniega, S. M., Brown, R., Shuler, K., Hamilton, I., Garcia, D. J., Doubal, F. N., Clancy, U., Sakka, E., Poliakova, T., Janssen, E., Duering, M., Ingrisch, M., Staals, J., ... Wardlaw, J. M. (2024). Cerebrovascular Function in Sporadic and Genetic Cerebral Small Vessel Disease. Annals of Neurology. Advance online publication. https://doi.org/10.1002/ana.27136
- Jaspers, T. J. M., Martens, B., Crawley, R., Jada, L., Amirrajab, S., Breeuwer, M., Holtackers, R. J., Chiribiri, A., & Scannell, C. M. (2024). Deep Learning Synthesis of White-Blood From Dark-Blood Late Gadolinium Enhancement Cardiac Magnetic Resonance. Investigative Radiology, 59(11), 767-773. https://doi.org/10.1097/RLI.0000000000001086
- Robbe, M. M. Q., Pinckaers, F. M. E., van Kuijk, S. M. J., van Oostenbrugge, R. J., van Zwam, W. H., & Postma, A. A. (2024). Post-endovascular therapy contrast extravasation in the mesial temporal region on dual-energy CT is associated with outcome in acute ischemic stroke patients. Journal of Stroke & Cerebrovascular Diseases, 33(11), Article 107949. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107949
- Jauregui, J., McClintock, A. H., Schrepel, C., Fainstad, T., Bierer, S. B., & Heeneman, S. (2024). You Get What You Reward: A Qualitative Study Exploring Medical Student Engagement in 2 Different Assessment Systems. Academic Medicine, 99(11), 1278-1285. Article 10.1097/ACM.0000000000005848. https://doi.org/10.1097/ACM.0000000000005848
- Medina, I., Wieland, E. B., Temmerman, L., Otten, J. J. T., Bermudez, B., Bot, I., Rademakers, T., Wijnands, E., Schurgers, L., Mees, B., van Berkel, T. J. C., Goossens, P., & Biessen, E. A. L. (2024). Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics. European Journal of Immunology, 54(11), Article 2350943. https://doi.org/10.1002/eji.202350943
- Zhao, D., Han, C., Mammadova-Bach, E., Watanabe-Kusunoki, K., Bandeira Honda, T. S., Li, Y., Li, C., Li, Q., Long, H., Lyubenov, L., Shi, C., Santovito, D., Weber, C., Boor, P., Droste, P., Parikh, S., Shapiro, J., De Chiara, L., Carangelo, G., ... Anders, H.-J. (2024). Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism-related vascular thrombosis with microvascular injury and its consequences. Kidney International, 106(5), 819-825. https://doi.org/10.1016/j.kint.2024.07.020
- Nies, H. M. J. M., Linz, D., Bijvoet, G. P., Holtackers, R. J., Luermans, J. G. L. M., van der Velden, K. E. H. M., Wildberger, J. E., Vernooy, K., van Kuijk, S. M. J., Mihl, C., & Chaldoupi, S. M. (2024). Local atrial bipolar electrogram voltage drops during cardiac magnetic resonance guided catheter ablation of typical atrial flutter: Associations with delivered radiofrequency energy and peri-procedural imaging. Heart Rhythm O2, 5(11), 778-787. https://doi.org/10.1016/j.hroo.2024.08.015
- Döring, Y., van der Vorst, E. P. C., & Weber, C. (2024). Targeting immune cell recruitment in atherosclerosis. Nature reviews. Cardiology, 21(11), 824-840. https://doi.org/10.1038/s41569-024-01023-z
- Kral, M., van der Vorst, E. P. C., Weber, C., & Doering, Y. (2024). (Multi-) omics studies of ILC2s in inflammation and metabolic diseases. Frontiers in Cell and Developmental Biology, 12, Article 1473616. https://doi.org/10.3389/fcell.2024.1473616
- Mourmans, S. G. J., Weerts, J., Baumert, M., Aizpurua, A. B., Achten, A., Knackstedt, C., Linz, D., & van Empel, V. P. M. (2024). Prognostic value of hypoxaemic burden from overnight oximetry in heart failure with preserved ejection fraction. Esc heart failure. https://doi.org/10.1002/ehf2.15116
- Mevenkamp, J., Bruls, Y. M. H., Mancilla, R., Grevendonk, L., Wildberger, J. E., Brouwers, K., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., Houtkooper, R. H., Buitinga, M., de Graaf, R. A., Lindeboom, L., & Schrauwen-Hinderling, V. B. (2024). Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T. Nature Communications, 15(1), Article 9159. https://doi.org/10.1038/s41467-024-53292-4
- Yoo, A. J., Zaidat, O. O., Sheth, S. A., Rai, A. T., Ortega-Gutierrez, S., Given, C. A., Zaidi, S. F., Grandhi, R., Cuellar, H., Mokin, M., Katz, J. M., Alshekhlee, A., Taqi, M. A., Ansari, S. A., Siddiqui, A. H., Barazangi, N., English, J. D., Maud, A., Kirmani, J., ... van Zwam, W. H. (2024). Thrombectomy for Stroke With Large Infarct on Noncontrast CT The TESLA Randomized Clinical Trial. JAMA-Journal of the American Medical Association, 332(16), 1355-1366. Article 13933. https://doi.org/10.1001/jama.2024.13933
- Al Enezy-Ulbrich, M. A., Belthle, T., Malyaran, H., Kucikas, V., Kuettner, H., de Lange, R. D., van Zandvoort, M., Neuss, S., & Pich, A. (2024). Fibrin Hydrogels Reinforced by Reactive Microgels for Stimulus-Triggered Drug Administration. Small, 20(42), Article 2309912. https://doi.org/10.1002/smll.202309912
- Ramos-Prada, A., Redondo-Rodríguez, A., Roca-Luque, I., Porta-Sánchez, A., Ter Bekke, R. M. A., Quintanilla, J. G., Sánchez-González, J., Peinado, R., Merino, J. L., Cluitmans, M., Holtackers, R. J., Marina-Breysse, M., Galán-Arriola, C., Enríquez-Vázquez, D., Vázquez-Calvo, S., Alfonso-Almazán, J. M., Pizarro, G., Ibáñez, B., González-Ferrer, J. J., ... Filgueiras-Rama, D. (2024). Novel systematic processing of cardiac magnetic resonance imaging identifies target regions associated with infarct-related ventricular tachycardia. EP Europace, 26(10), Article euae244. https://doi.org/10.1093/europace/euae244
- van Nijnatten, T. J. A., de Mooij, C. M., Mitea, C., Houwers, J., de Boer, M., Smidt, M. L., Mottaghy, F. M., & Wildberger, J. E. (2024). [18F]FDG whole-body PET-MR including an integrated breast MR protocol for locoregional and distant staging in breast cancer patients-a feasibility study. Insights into Imaging, 15(1), Article 243. https://doi.org/10.1186/s13244-024-01830-5
- Santovito, D., Henderson, J. M., Bidzhekov, K., Triantafyllidou, V., Jansen, Y., Chen, Z., Farina, F. M., Diagel, A., Aslani, M., Blanchet, X., Schunkert, H., Megens, R. T. A., Doering, Y., Sattler, M., & Weber, C. (2024). Mex3a Protects Against Atherosclerosis: Evidence From Mice and Humans. Circulation, 150(15), 1213-1216. https://doi.org/10.1161/CIRCULATIONAHA.124.069526
- Kassem, M., Crombag, G. A. J. C., Stegers, J., Liem, M. I., Koornstra, E., Schreuder, F. H. B. M., van Dam-Nolen, D. H. K., Lucci, C., van der Geest, R. J., Daemen, M. J., van der Steen, A. F. W., Hendrikse, J., Mess, W. H., Bos, D., Wildberger, J. E., van Oostenbruggeb, R. J., Nederkoorn, P. J., & Kooi, M. E. (2024). Association between Antiplatelet Therapy and Changes in Intraplaque Hemorrhage in Patients with Mild to Moderate Symptomatic Carotid Stenosis: a longitudinal MRI study. Cerebrovascular Diseases, 53(5), 598-606. https://doi.org/10.1159/000535274
- van den Kerkhof, M., de Jong, J. J. A., Voorter, P. H. M., Postma, A., Kroon, A. A., van Oostenbrugge, R. J., Jansen, J. F. A., & Backes, W. H. (2024). Blood-Brain Barrier Integrity Decreases With Higher Blood Pressure: A 7T DCE-MRI Study. Hypertension, 81(10), 2162-2172. https://doi.org/10.1161/HYPERTENSIONAHA.123.22617