Uli Schotten

Professor

Professor Uli Schotten studied medicine at the universities of Aachen, Glasgow, and Valetta. After four years of training in cardiology at the University Hospital of Aachen, he joined the Department of Physiology at Maastricht University in 1998, first as a scholar of the Academy of Sciences of North-Rhine Westfalia and from 1999 on as a staff member of the department. He defended his thesis 'Mechanisms of Atrial Paralysis in Atrial Fibrillation' at Maastricht University in 2003, and received his habilitation in Experimental Cardiology at the University Hospital in Aachen in 2004. Since 2007, he is Principal Investigator at CARIM. In 2011, he was appointed Professor of Cardiac Electrophysiology and became chairman of the Department of Physiology in 2019.

His research interests include cellular and integrated actions of antiarrhythmic drugs, the development of substrates for the perpetuation of atrial fibrillation, invasive and non-invasive quantification of the substrate of atrial fibrillation, interaction between atrial fibrillation and activation of the coagulation system, and three-dimensional computer models of atrial fibrillation. He is coordinator of the CVON network RACE V and PI in numerous national and international research networks. He was member of the European task force for the development of the ESC guidelines for management of atrial fibrillation in 2010, 2012, and 2016. Furthermore, he is member of the Executive Committee of the Network of Competence for Atrial Fibrillation (AFNET), co-founder of the Maastricht University spin-off company YourRhythmics BV, and acts as the chairman of the Strategic board of CARIM.

Department of Physiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 3.130
T: +31(0)43 388 12 00

2024
- Hutschalik, T., Özgül, O., Casini, M., Szabó, B., Peyronnet, R., Bártulos, Ó., Argenziano, M., Schotten, U., & Matsa, E. (2024). Immune response caused by M1 macrophages elicits atrial fibrillation-like phenotypes in coculture model with isogenic hiPSC-derived cardiomyocytes. Stem Cell Research & Therapy, 15(1), Article 280. https://doi.org/10.1186/s13287-024-03814-0
- Schotten, U., Goette, A., & Verheule, S. (2024). Translation of pathophysiological mechanisms of atrial fibrosis into new diagnostic and therapeutic approaches. Nature Reviews Cardiology. Advance online publication. https://doi.org/10.1038/s41569-024-01088-w
- Bijvoet, G. P., Hermans, B. J. M., Linz, D., Luermans, J. G. L. M., Maesen, B., Nijveldt, R., Mihl, C., Vernooy, K., Wildberger, J. E., Holtackers, R. J., Schotten, U., & Chaldoupi, S.-M. (2024). Optimal Threshold and Interpatient Variability in Left Atrial Ablation Scar Assessment by Dark-Blood LGE CMR. JACC: Clinical Electrophysiology, 10(10), 2186-2197. https://doi.org/10.1016/j.jacep.2024.05.017
- Schnabel, R. B., Benezet-Mazuecos, J., Becher, N., McIntyre, W. F., Fierenz, A., Lee, S. F., Goette, A., Atar, D., Bertaglia, E., Benz, A. P., Chlouverakis, G., Birnie, D. H., Dichtl, W., Blomstrom-Lundqvist, C., Camm, A. J., Erath, J. W., Simantirakis, E., Kutyifa, V., Lip, G. Y. H., ... Kirchhof, P. (2024). Anticoagulation in device-detected atrial fibrillation with or without vascular disease: a combined analysis of the NOAH-AFNET 6 and ARTESiA trials. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae596
- Goette, A., Corradi, D., Dobrev, D., Aguinaga, L., Cabrera, J.-A., Chugh, S. S., de Groot, J. R., Soulat-Dufour, L., Fenelon, G., Hatem, S. N., Jalife, J., Lin, Y.-J., Lip, G. Y. H., Marcus, G. M., Murray, K. T., Pak, H.-N., Schotten, U., Takahashi, N., Yamaguchi, T., ... Nattel, S. (2024). Atrial Cardiomyopathy Revisited - Evolution of a Concept. A Clinical Consensus Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Association (APHRS), and the Latin American Heart Rhythm Society (LAHRS): a clinical consensus statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asian Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS). EP Europace, 26(9), Article euae204. https://doi.org/10.1093/europace/euae204
- Fabritz, L., Al-Taie, C., Borof, K., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Roth Cardoso, V., Chua, W., van Elferen, S., Eckardt, L., Gkoutos, G., Goette, A., Guasch, E., Hatem, S., Metzner, A., Mont, L., Murukutla, V. A., Obergassel, J., Rillig, A., ... Kirchhof, P. (2024). Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae611
- Diener, H. C., Becher, N., Sehner, S., Toennis, T., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G.-A., Dichtl, W., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lip, G. Y. H., Lubinski, A., ... NOAH-AFNET 6 investigators (2024). Anticoagulation in Patients With Device-Detected Atrial Fibrillation With and Without a Prior Stroke or Transient Ischemic Attack: The NOAH-AFNET 6 Trial. Journal of the American Heart Association, 13(17), e036429. https://doi.org/10.1161/JAHA.124.036429
- Reyat, J. S., Sommerfeld, L. C., O'Reilly, M., Cardoso, V. R., Thiemann, E., Khan, A. O., O'Shea, C., Harder, S., Müller, C., Barlow, J., Stapley, R. J., Chua, W., Kabir, S. N., Grech, O., Hummel, O., Hübner, N., Kääb, S., Mont, L., Hatem, S. N., ... Fabritz, L. (2024). PITX2 deficiency leads to atrial mitochondrial dysfunction. Cardiovascular Research. Advance online publication. https://doi.org/10.1093/cvr/cvae169
- Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2024). Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery. Heart Rhythm. Advance online publication. https://doi.org/10.1016/j.hrthm.2024.08.014
- van Hunnik, A., Sobota, V., Zeemering, S., Opacic, D., Scaf, B., D'Alessandro, E., Oyaert, K., Kuiper, M., Diness, J. G., Sorensen, U. S., Milnes, J. T., van der Heyden, M. A. G., Jespersen, T., Schotten, U., & Verheule, S. (2024). Analysis of drug-induced and spontaneous cardioversions reveals similar patterns leading to termination of atrial fibrillation. Frontiers in physiology, 15, Article 1399037. https://doi.org/10.3389/fphys.2024.1399037

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Uli Schotten

Professor