Eline Kooi

Professor

Prof. Eline Kooi obtained a Master degree in Physics (University of Amsterdam, 1995) and a PhD degree in Molecular Physics at the same university (1999). She was trained in Medical Physics, specialisation Radiology, at Maastricht UMC from 1999-2004. Since 2004 she is a registered Medical Physicist at Maastricht UMC+. Presently, she is a Professor of Medical Physics, especially vascular imaging, at the Department of Radiology and Nuclear Medicine within CARIM.

Her research is focussed on sophisticated multi-modality cardiovascular imaging. Her group is at the international forefront of developing and evaluating imaging techniques to study plaque vulnerability. She has focussed on cutting edge imaging of the hallmarks of high-risk plaques in animals and patients. She was the first to demonstrate that plaque inflammation can be visualised in humans. Her group has the unique position of multi-modality imaging of the vessel wall (PET/MRI, ultrasound, CT) in different vascular beds (carotid and coronary arteries, aorta). She has performed numerous MR Spectroscopy studies on lipid metabolism, also in the heart. Recently, she has expanded her research towards cardiac MRI (perfusion MRI, T1 mapping).

She is a leading member of the steering committee of a multi-centre trial to determine the clinical value of plaque imaging (PARISK) and she coordinates plaque imaging within the European Carotid Surgery Trial-2 (ECST-2). She has published >100 scientific publications in international peer-reviewed journals. She has successfully completed supervision of 12 PhD students. Currently, she is supervising 6 PhD students and one post-doc student. She is frequently invited as invited speaker and/or moderator at the leading international conferences in her field. She has received numerous research grants.

Department of Radiology and Nuclear Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H1.328
T: +31(0)43 387 49 11

 

  • 2024
    • van Oeteren, M. A. J., Simons, N., Simons, P. I. H. G., van de Waarenburg, M. P. H., Kooi, M. E., Feskens, E. J. M., van der Ploeg, E. M. C. L., Van den Eynde, M. D. G., Houben, A. J. H. M., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2024). Fructose restriction has beneficial effects on adipose tissue distribution but not on serum adipokine levels: Post-hoc analysis of a double-blind randomized controlled trial. Clinical Obesity, Article 12714. Advance online publication. https://doi.org/10.1111/cob.12714
    • Kassem, M., Crombag, G. A. J. C., Stegers, J., Liem, M. I., Koornstra, E., Schreuder, F. H. B. M., van Dam-Nolen, D. H. K., Lucci, C., van der Geest, R. J., Daemen, M. J., van der Steen, A. F. W., Hendrikse, J., Mess, W. H., Bos, D., Wildberger, J. E., van Oostenbruggeb, R. J., Nederkoorn, P. J., & Kooi, M. E. (2024). Association between Antiplatelet Therapy and Changes in Intraplaque Hemorrhage in Patients with Mild to Moderate Symptomatic Carotid Stenosis: a longitudinal MRI study. Cerebrovascular Diseases, 53(5), 598-606. https://doi.org/10.1159/000535274
    • Fandler-Höfler, S., Eppinger, S., Ambler, G., Nash, P., Kneihsl, M., Lee, K. J., Lim, J. S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., ... Microbleeds International Collaborative Network (2024). Sex Differences in Frequency, Severity, and Distribution of Cerebral Microbleeds. Jama network open, 7(10), Article e2439571. https://doi.org/10.1001/jamanetworkopen.2024.39571
    • Brandt, Y., Lubrecht, J. M., Adriaans, B. P., Aben, J.-P., Gerretsen, S. C., Ghossein-Doha, C., Spaanderman, M. E. A., Prinzen, F. W., & Kooi, M. E. (2024). Quantification of left ventricular myocardial strain: Comparison between MRI tagging, MRI feature tracking, and ultrasound speckle tracking. NMR in Biomedicine, 37(9), Article e5164. https://doi.org/10.1002/nbm.5164
    • Nies, K. P. H., Aizaz, M., van Dam-Nolen, D. H. K., Goring, T. C. D., Schreuder, T. A. H. C. M. L., van Orshoven, N. P., Postma, A. A., Bos, D., Hendrikse, J., Nederkoorn, P., van der Geest, R., van Oostenbrugge, R. J., Mess, W. H., & Kooi, M. E. (2024). Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: the Plaque At RISK (PARISK) study. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 26(2), Article 101049. https://doi.org/10.1016/j.jocmr.2024.101049
    • Aizaz, M., van der Pol, J. A. J., Schneider, A., Munoz, C., Holtackers, R. J., van Cauteren, Y., van Langen, H., Meeder, J. G., Rahel, B. M., Wierts, R., Botnar, R. M., Prieto, C., Moonen, R. P. M., & Kooi, M. E. (2024). Extended MRI-based PET motion correction for cardiac PET/MRI. EJNMMI Physics, 11(1), Article 36. https://doi.org/10.1186/s40658-024-00637-z
    • Brandt, Y., Alers, R.-J., Canjels, L. P. W., Jorissen, L. M., Jansen, G., Janssen, E. B. N. J., van Kuijk, S., Went, T. M., Koehn, D., Gerretsen, S. C., Jansen, J., Backes, W., Hurks, P. P. M., van de Ven, V., Kooi, M. E., Spaanderman, M. E. A., & Ghossein-Doha, C. (2024). DEcreased Cognitive functiON, NEurovascular CorrelaTes and myocardial changes in women with a history of pre-eclampsia (DECONNECT): research protocol for a cross-sectional pilot study. BMJ Open, 14(3), Article e077534. https://doi.org/10.1136/bmjopen-2023-077534
    • Saba, L., Cau, R., Murgia, A., Nicolaides, A. N., Wintermark, M., Castillo, M., Staub, D., Kakkos, S., Yang, Q., Paraskevas, K. I., Yuan, C., Edjlali, M., Sanfilippo, R., Hendrikse, J., Johansson, E., Mossa-Basha, M., Balu, N., Dichgans, M., Saloner, D., ... Et al. (2024). Carotid Plaque-RADS, a novel stroke risk classification system. JACC-Cardiovascular Imaging, 17(1), 62-75. https://doi.org/10.1016/j.jcmg.2023.09.005
  • 2023
    • Camarasa, R., Kervadec, H., Kooi, M. E., Hendrikse, J., Nederkoorn, P. J., Bos, D., & de Bruijne, M. (2023). Nested star-shaped objects segmentation using diameter annotations. Medical Image Analysis, 90(1), Article 102934. https://doi.org/10.1016/j.media.2023.102934
    • Ren, Z., Bosma, H., Wesselius, A., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., Koster, A., van Greevenbroek, M. M. J., Dagnelie, P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Traditional lifestyle factors partly mediate the association of socioeconomic position with intrahepatic lipid content: The Maastricht study. JHEP Reports, 5(11), Article 100855. https://doi.org/10.1016/j.jhepr.2023.100855