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MLDS grant Sabine Daemen

MLDS grant Sabine Daemen

15 November 2024

Dr Sabine Daemen (Dept of Internal Medicine) received a Career Development Grant (160k) from the Dutch Digestive Foundation (MLDS).

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Our new Division Leaders

Our new Division Leaders

3 October 2024

As of 1 October 2024, Casper Schalkwijk and Joost Lumens have been appointed as Division Leaders Vessels and Heart. Judith Sluimer will success Hugo ten Cate as Division Leader Blood in March 2025.

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Carim Maastricht
Carim Maastricht

Dominik Linz

Professor

Prof Dominik Linz is a clinician-scientist who received his PhD from Maastricht University, The Netherlands, in 2013 (Prof. U. Schotten) and completed his Cardiology training in Homburg/Saar, Germany, in 2017 (Prof. M. Böhm). In 2017, he was recruited as an Associate Professor and clinical EP-fellow to Adelaide to initiate and drive a translational research programme focussing on atrial fibrillation and sleep disordered breathing at the Royal Adelaide Hospital and University of Adelaide (Prof. P. Sanders). Since 2019, Dr Dominik Linz is a Staff member and consultant clinician at the Heart+Vascular Center, Maastricht UMC+.

Over the past years Prof. Dominik Linz has developed a National and International reputation in the field of cardiac arrhythmia research. The focus of this work has been to understand the pathophysiology and mechanisms underlying atrial arrhythmias and the development of treatment approaches. This research has broadly included: (i) Work describing sleep apnoea associated electrophysiological changes in the atria increasing atrial fibrillation susceptibility. (ii) Description of antiarrhythmic effects of autonomic modulation by renal sympathetic denervation under different pathophysiological conditions. (iii) Work describing the role of the lysosomal carboxypeptidase cathepsin A in the development of an atrial arrhythmogenic substrates. Ongoing research is mainly focused on risk factor modification and preventive interventions for AF.

As of January 2024, Dominik Linz (Department of Cardiology) has been appointed as a professor at Maastricht University. The title of his position is 'Comprehensive Atrial Fibrillation Management.

Dominik-linz

Department of Cardiology

 

  • 2024
    • Velt, M. J. H., Crijns, H. J. G. M., van Gelder, I. C., Linz, D., van de Lande, M. E., Ten Cate, H., Spronk, H. M. H., de Melis, M., Rienstra, M., & Mulder, B. A. (2024). Dynamic biomarker profiles in patients with paroxysmal atrial fibrillation: Assessing the differences between sinus rhythm and acute atrial fibrillation episode. International Journal of Cardiology, 417, Article 132526. https://doi.org/10.1016/j.ijcard.2024.132526
    • Mourmans, S. G. J., Weerts, J., Baumert, M., Aizpurua, A. B., Achten, A., Knackstedt, C., Linz, D., & van Empel, V. P. M. (2024). Prognostic value of hypoxaemic burden from overnight oximetry in heart failure with preserved ejection fraction. Esc heart failure. Advance online publication. https://doi.org/10.1002/ehf2.15116
    • Gawalko, M., Middeldorp, M. E., Saljic, A., Penders, J., Jespersen, T., Albert, C. M., Marcus, G. M., Wong, C. X., Sanders, P., & Linz, D. (2024). Diet and risk of atrial fibrillation: a systematic review. European Heart Journal, 45(40), 4259-4274. Article ehae551. https://doi.org/10.1093/eurheartj/ehae551
    • Joza, J., Burri, H., Andrade, J. G., Linz, D., Ellenbogen, K. A., & Vernooy, K. (2024). Atrioventricular node ablation for atrial fibrillation in the era of conduction system pacing. European Heart Journal, Article ehae656. https://doi.org/10.1093/eurheartj/ehae656
    • Gottlieb, L. A., Mahfoud, F., Stavrakis, S., Jespersen, T., & Linz, D. (2024). Autonomic Nervous System: A Therapeutic Target for Cardiac End-Organ Damage in Hypertension. Hypertension, 81(10), 2027-2037. Article 19460. https://doi.org/10.1161/HYPERTENSIONAHA.123.19460
    • Chaldoupi, S.-M., Nissen, S. D., Vriesendorp, P. A., Jerltorp, K., Farnir, F. I. P., Linz, B., Johannessen, A., Haugdal, M. A., Luermans, J. G. L. M., Saljic, A., Jespersen, T., Hansen, J., & Linz, D. (2024). Focal monopolar pulsed field ablation from within the great cardiac vein for idiopathic premature ventricular contractions after failed radiofrequency ablation. Heart Rhythm, 21(10), 1877-1887. https://doi.org/10.1016/j.hrthm.2024.07.002
    • Bijvoet, G. P., Hermans, B. J. M., Linz, D., Luermans, J. G. L. M., Maesen, B., Nijveldt, R., Mihl, C., Vernooy, K., Wildberger, J. E., Holtackers, R. J., Schotten, U., & Chaldoupi, S.-M. (2024). Optimal Threshold and Interpatient Variability in Left Atrial Ablation Scar Assessment by Dark-Blood LGE CMR. JACC: Clinical Electrophysiology, 10(10), 2186-2197. https://doi.org/10.1016/j.jacep.2024.05.017
    • Sandgren, E., Hermans, A. N., Gawalko, M., Betz, K., Sohaib, A., Fung, C. H., Hillmann, H. A., van der Velden, R. M., Verhaert, D., Scherr, D., Sultan, A., Steven, D., Pisters, R., Hemels, M., Lodzinski, P., Chaldoupi, S.-M., Gupta, D., Gruwez, H., Pluymaekers, N. A., ... TeleCheck-AF investigators (2024). Smartphone app-based approximation of time spent with atrial fibrillation and symptoms in patients after catheter ablation: Data from the TeleCheck-AF project. EP Europace, 26(10), Article euae247. https://doi.org/10.1093/europace/euae247
    • Rijks, J. H. J., Heckman, L., Westra, S., Cornelussen, R., Ghosh, S., Curila, K., Smisek, R., Grieco, D., Bressi, E., Nguyen, U. C., Lumens, J., van Stipdonk, A. M. W., Linz, D., Prinzen, F. W., Luermans, J. G. L. M., & Vernooy, K. (2024). Assessment of ventricular electrical heterogeneity in left bundle branch pacing and left ventricular septal pacing by using various electrophysiological methods. Journal of Cardiovascular Electrophysiology, Article 16435. https://doi.org/10.1111/jce.16435
    • Malik, V., Linz, D., & Sanders, P. (2024). The Role of the Autonomic Nervous System as Both “Trigger and “Substrate” in Atrial Fibrillation. Cardiac Electrophysiology Clinics, 16(3), 271-280. https://doi.org/10.1016/j.ccep.2023.08.003
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