Ben Janssen

Associate professor

Dr Ben Janssen graduated with the specialisation physiology and endocrinology at the Faculty of Biology of the University of Nijmegen (1983). He received his PhD with a thesis on ‘sensory renal nerves and hypertension’ at the Department of Pharmacology of Maastricht University (1988). Since then, he has been full member of the staff of the Department of Pharmacology and was appointed associate professor and teaching coordinator Pharmacology at the medical faculty in 2004. He enjoyed several cardiovascular research trainings in institutes across the USA and has worked for one year (1995) at Baker Medical Research Institute, Melbourne, Australia in the laboratory of Prof. Head (autonomic pharmacology).

His main research line focusses on integrative pharmacological control of autonomic function in cardiovascular disease. He has considerable experience in translating pharmacological research in vitro to hypothesis testing in vivo experimental animals and has specialised in baroreflex control of the circulation as well as circadian rhythms.

His current research area is related to the role of the kidney in the (perinatal) development of hypertension. He is sponsored by the Dutch Kidney Foundation on a project on the role of hypoxia in the development of chronic kidney disease. In these studies he makes use of state of the art in vivo telemetric recordings of tissue oxygen.

Department of Pharmacology & Toxicology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 4.260
T: +31(0)43 388 13 47

2024
- Piët, J. D., Booth, A., Donker, E. M., de Ponti, F., Lunghi, C., Poluzzi, E., Janssen, B. J. A., Tun, S., Bekker, C., Dima, L., Costa, J., Jalving, M., Oude Munnink, T. H., van den Bemt, P. M. L. A., Labriffe, M., van Emden, T., van Waardenburg, V., Likic, R., Richir, M., ... Tichelaar, J. (2024). Environmentally sustainable prescribing: recommendations for EU pharmaceutical legislation. The Lancet. Planetary health, 8(10), e715-e716. https://doi.org/10.1016/S2542-5196(24)00230-4
2023
- Donker, E. M., Osmani, H., Brinkman, D. J., van Rosse, F., Janssen, B., Knol, W., Dumont, G., Jorens, P. G., Dupont, A., Christiaens, T., van Smeden, J., de Waard-Siebinga, I., Peeters, L. E. J., Goorden, R., Hessel, M., Lissenberg-Witte, B. I., Richir, M. C., van Agtmael, M. A., Kramers, C., ... Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2023). The impact of a summative national prescribing assessment and curriculum type on the development of the prescribing competence of junior doctors. European Journal of Clinical Pharmacology, 79(12), 1613 - 1621. https://doi.org/10.1007/s00228-023-03567-4
- Donker, E. M., Pandit, R., Poleij, M. C. S., Brinkman, D. J., van Agtmael, M. A., van Rosse, F., Dumont, G., Kramers, C., Atiqi, R., Richir, M. C., van Smeden, J., Hessel, M. H. M., Janssen, B. J., Knol, W., Tichelaar, J., & Pharmacotherapy Education working group of the Dutch Society for Clinical Pharmacology & Biopharmacy and its affiliated Dutch Network of Clinical Pharmacology Teachers (2023). The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study. British Journal of Clinical Pharmacology, 89(4), 1431-1451. https://doi.org/10.1111/bcp.15606
2022
- Donker, E. M., Brinkman, D. J., van Rosse, F., Janssen, B., Knol, W., Dumont, G., Jorens, P. G., Dupont, A., Christiaens, T., van Smeden, J., de Waard-Siebinga, I., Peeters, L. E. J., Goorden, R., Hessel, M., Lissenberg-Witte, B., Richir, M., van Agtmael, M., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2022). Do we become better prescribers after graduation: A 1-year international follow-up study among junior doctors. British Journal of Clinical Pharmacology, 88(12), 5218-5226. https://doi.org/10.1111/bcp.15443
2020
- Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A., & Janssen, B. J. (2020). Haemodynamic effects of the flavonoid quercetin in rats revisited. British Journal of Pharmacology, 177(8), 1841-1852. https://doi.org/10.1111/bph.14955
2019
- Daskalopoulos, E. P., Hermans, K. C. M., Debets, J., Strzelecka, A., Leenders, P., Vervoort-Peters, L., Janssen, B. J. A., & Blankesteijn, W. M. (2019). The Beneficial Effects of UM206 on Wound Healing After Myocardial Infarction in Mice Are Lost in Follow-Up Experiments. Frontiers in Cardiovascular Medicine, 6, Article 118. https://doi.org/10.3389/fcvm.2019.00118
- Jansen, D. R. M., Keijsers, C. J. P. W., Kornelissen, M. O., Rikkert, M. G. M. O., Kramers, C., Tichelaar, J., Janssen, B., van den Brink, A. M., Peeters, L., Dumont, G., Hessel, M., Rissmann, R., Knol, W., & Education working group of the Dutch Society for Clinical Pharmacology and Biopharmacy (2019). Towards a "prescribing license" for medical students: development and quality evaluation of an assessment for safe prescribing. European Journal of Clinical Pharmacology, 75(9), 1261-1268. https://doi.org/10.1007/s00228-019-02686-1
2018
- Emans, T. W., Patinha, D., Joles, J. A., Koeners, M. P., Janssen, B. J., & Krediet, C. T. P. (2018). Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation. Scientific Reports, 8(1), Article 16342. https://doi.org/10.1038/s41598-018-34211-2
- Emans, T. W., Janssen, B. J., Joles, J. A., & Krediet, C. T. P. (2018). Nitric Oxide Synthase Inhibition Induces Renal Medullary Hypoxia in Conscious Rats. Journal of the American Heart Association, 7(15), Article 009501. https://doi.org/10.1161/JAHA.118.009501
- Chennupati, R., Meens, M. J., Janssen, B. J., van Dijk, P., Hakvoort, T. B. M., Lamers, W. H., De Mey, J. G. R., & Koehler, S. E. (2018). Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice. Physiological Reports, 6(11), Article 13717. https://doi.org/10.14814/phy2.13717

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Ben Janssen

Associate professor